Hotels with Suites in South San Diego from $110
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Top South San Diego Hotels with Suites

Holiday Inn Express San Diego South - Chula Vista by IHG
632 E Street Chula Vista CA
Free Cancellation
$129 nightly
The price is $142 total per night
$142 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
Free Cancellation
$119 nightly
The price is $135 total per night
$135 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Quality Suites San Diego Otay Mesa
2351 Otay Center Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $120 total per night
$120 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...

Howard Johnson Suites by Wyndham San Diego Chula Vista/BayFt
235 Woodlawn Ave Chula Vista CA
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $110 total per night
$110 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South San Diego hotels essential information
Accommodation | 7,785 hotels |
|---|---|
Lowest Price | $110 |
Highest Price | $142 |
Popular hotels | Howard Johnson Suites by Wyndham San Diego Chula Vista/BayFt, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, Quality Suites San Diego Otay Mesa, Holiday Inn Express San Diego South - Chula Vista by IHG |
Recent South San Diego hotel reviews by fellow wanderers

Sheraton San Diego Resort
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Shuttle was easy to find
"
A verified traveler stayed at Sheraton San Diego Resort

Hard Rock Hotel San Diego
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"Clean room
Close to nice area"
A verified traveler stayed at Hard Rock Hotel San Diego
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