Explore 20 Luxury Hotels in Santa Cruz

Name: EME Catedral Mercer Hotel
Price range: $186 total
Rating: 8.6

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Best Luxury Hotels in Santa Cruz

Hotel Boutique Casa del Poeta Sevilla

Don Carlos Alonso Chaparro 3, Seville, Seville

Fully refundableReserve now, pay when you stay

A bar/lounge and a 24-hour front desk are featured at this hotel, along with valet parking. WiFi in public areas is free. A coffee shop, a terrace, and a snack ...

9.8/10 Exceptional! (798 reviews)

"Everything about this hotel was amazing! From being greeted to sitting down and having a cocktail while listening to a guitarist play during the check-in process set the bar extremely high our room was the family room, extremely spacious and comfortable!"

Reviewed on Jul 22, 2025

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Hotel Amadeus Sevilla

Calle Farnesio 6, Seville, Seville

Fully refundableReserve now, pay when you stay

$145 nightly

$160 total

Aug 25 - Aug 26

Total includes taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a coffee shop, and ...

9.6/10 Exceptional! (1,009 reviews)

"The hotel staff were all incredibly friendly and super helpful. The hotel decor was beautiful and the rooms were well presented. We would definitely stay again"

Reviewed on Jul 22, 2025

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2, Seville, Seville

Fully refundableReserve now, pay when you stay

$324 nightly

$357 total

Aug 3 - Aug 4

Total includes taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.4/10 Exceptional! (995 reviews)

"It was fantastic--would definitely stay here again!"

Reviewed on Jul 22, 2025

El Rey Moro Hotel Boutique

Reinoso, 8, Seville, Seville

Fully refundableReserve now, pay when you stay

$181 nightly

$199 total

Aug 25 - Aug 26

Total includes taxes and fees

This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Enjoy the hot tub and perks like free WiFi. A terrace, a snack bar/deli, and a library ...

9.4/10 Exceptional! (858 reviews)

"The staff was amazing and very helpful, the restaurant was great and the patio actually looked like the picture!!!!"

Reviewed on Jul 20, 2025

Hotel Fernando III

San Jose 21, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.4/10 Exceptional! (1,518 reviews)

Recent birthday celebratory break

"Stayed here recently for a friends 50th birthday, we had tickets to see kylie minogue in Seville. Our rooms were clean and comfortable. Can’t comment on the breakfast buffet as none of us included this with our stay. Staff on reception were very friendly and helpful"

Reviewed on Jul 21, 2025

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Hotel Boutique Palacio Pinello

Calle Segovia, 1, Seville, Seville

Fully refundableReserve now, pay when you stay

$73 nightly

$81 total

Jul 28 - Jul 29

Total includes taxes and fees

This hotel features a rooftop terrace and a bar/lounge. WiFi in public areas is free. A business center, a terrace, and a snack bar/deli are also on offer.

9.4/10 Exceptional! (629 reviews)

Beautiful Hotel with Friendly Staff

"The check-in process was easy and staff were extremely nice! We loved our room - very comfortable beds and loved the old exposed wood ceiling in our room. We were able to walk yo many restaurants and shops nearby! Highly recommend!"

Reviewed on Jul 9, 2025

Las Casas de la Juderia

Calle Santa Maria La Blanca 5, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a full-service spa and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...

9.2/10 Wonderful! (1,002 reviews)

"Amazing place to stay, loved it!"

Reviewed on Jul 13, 2025

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EME Catedral Mercer Hotel

Calle Alemanes 27, Seville, Seville

Fully refundableReserve now, pay when you stay

$169 nightly

$186 total

Aug 25 - Aug 26

Total includes taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Enjoy the a rooftop ...

8.6/10 Excellent! (994 reviews)

"Excellent property and location. old building with the charm but modern finishes. Mario on the front-desk was amazing and helpful. center of the Cathedral which means late night noise is assumed. we did get bothered a bit but also wanted to be in the middle of it. thanks"

Reviewed on Jul 22, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Santa Cruz

Hotel Boutique Palacio Pinello

Calle Segovia, 1, Seville, Seville

$73 nightly

$81 total

Jul 28 - Jul 29

Total includes taxes and fees

9.4/10 Exceptional! (629 reviews)

5 star hotels in Santa Cruz

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2, Seville, Seville

$324 nightly

$357 total

Aug 3 - Aug 4

Total includes taxes and fees

9.4/10 Exceptional! (995 reviews)

Santa Cruz Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Santa Cruz luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Santa Cruz to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Santa Cruz will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Santa Cruz, and plan your next opulent escape.

Santa Cruz hotels essential information

Accommodation	410 hotels
Lowest Price	$57
Highest Price	$357
Popular hotels	Hotel Alfonso XIII, a Luxury Collection Hotel, Seville, EME Catedral Mercer Hotel, El Rey Moro Hotel Boutique, Hotel Boutique Casa del Poeta Sevilla, Las Casas de la Juderia, Hotel Fernando III, Hotel Amadeus Sevilla, Hotel Boutique Palacio Pinello

Popular Luxury Stays in Santa Cruz

Recent Santa Cruz Hotel Reviews By Fellow Wanderers

Hotel Rey Alfonso X

5 out of 5

Posted 10 hours ago

Travelocity Verified Review

"This hotel was lovely. Great location for exploring. Facilities new and really clean. Rooms spacious and well kitted out. Pool top area amazing. Wonderful stay with really friendly staff. We will return. Thank you"

A verified traveler stayed at Hotel Rey Alfonso X