Explore 20 Luxury Hotels in Santa Cruz

Name: EME Catedral Mercer Hotel
Rating: 8.6

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Best Luxury Hotels in Santa Cruz

Hotel Boutique Casa del Poeta Sevilla

Don Carlos Alonso Chaparro 3, Seville, Seville

Fully refundableReserve now, pay when you stay

A bar/lounge and a 24-hour front desk are featured at this hotel, along with valet parking. WiFi in public areas is free. A coffee shop, a terrace, and a snack ...

9.8/10 Exceptional! (783 reviews)

"Awesome Apartment por 4 Guests, very spacious and luxurious, unbeatablelocation. Highly recommended!"

Reviewed on Jun 3, 2025

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Hotel Amadeus Sevilla

Calle Farnesio 6, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a coffee shop, and ...

9.6/10 Exceptional! (1,004 reviews)

Reviewed on Jun 7, 2025

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Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2, Seville, Seville

Fully refundableReserve now, pay when you stay

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.4/10 Exceptional! (992 reviews)

Exceptional Stay with Outstanding Service f

"I recently stayed at Alfonso XIII and had an exceptional experience, especially as someone traveling with a service dog. From the moment we arrived, the staff went above and beyond to ensure both my dog and I felt welcome and comfortable. The check-in process was seamless, and I was pleasantly surprised ..."

Reviewed on May 20, 2025

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El Rey Moro Hotel Boutique

Reinoso, 8, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Enjoy the hot tub and perks like free WiFi. A terrace, a snack bar/deli, and a library ...

9.4/10 Exceptional! (848 reviews)

"This boutique hotel was very beautiful with lots of color, antique furniture, and flowers. It was nice to have the option to sit outside the room and relax. The only issue is it can be noisy in the morning with the breakfast service."

Reviewed on May 29, 2025

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Hotel Fernando III

San Jose 21, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.4/10 Exceptional! (1,504 reviews)

"Great location and hotel."

Reviewed on Jun 4, 2025

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Hotel Boutique Palacio Pinello

Calle Segovia, 1, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a rooftop terrace and a bar/lounge. WiFi in public areas is free. A business center, a terrace, and a snack bar/deli are also on offer.

9.4/10 Exceptional! (618 reviews)

"Great area, walkable to all the attractions. The decor was beautiful in yhe hotel."

Reviewed on Jun 6, 2025

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Las Casas de la Juderia

Calle Santa Maria La Blanca 5, Seville, Seville

Fully refundableReserve now, pay when you stay

This hotel features a full-service spa and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...

9.2/10 Wonderful! (1,007 reviews)

"The property was in the older part of the city which made the location attractive. The hotel had a lot of character as well. The staff was exceptionally helpful."

Reviewed on Jun 4, 2025

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EME Catedral Mercer Hotel

Calle Alemanes 27, Seville, Seville

Fully refundableReserve now, pay when you stay

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Enjoy the a rooftop ...

8.6/10 Excellent! (988 reviews)

"The location was the closest hotel to the cathedral which was amazing but get ready to hear church bells!"

Reviewed on Jun 1, 2025

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More 4 star hotels in Santa Cruz

Hotel Boutique Palacio Pinello

Calle Segovia, 1, Seville, Seville

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9.4/10 Exceptional! (618 reviews)

5 star hotels in Santa Cruz

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2, Seville, Seville

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9.4/10 Exceptional! (992 reviews)

Santa Cruz Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Santa Cruz luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Santa Cruz to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Santa Cruz will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Santa Cruz, and plan your next opulent escape.

Santa Cruz hotels essential information

Accommodation	403 hotels
Lowest Price
Highest Price
Popular hotels	Hotel Alfonso XIII, a Luxury Collection Hotel, Seville, EME Catedral Mercer Hotel, El Rey Moro Hotel Boutique, Hotel Boutique Casa del Poeta Sevilla, Las Casas de la Juderia, Hotel Fernando III, Hotel Amadeus Sevilla, Hotel Boutique Palacio Pinello

Popular Luxury Stays in Santa Cruz

Recent Santa Cruz Hotel Reviews By Fellow Wanderers

Hotel Amadeus Sevilla

5 out of 5

Posted 23 hours ago

Travelocity Verified Review

"Excellent location in the heart of the historic centre, and yet a really tranquil and serene oasis. The roof top area offered a small pool and jacuzzi to cool off in after a busy and hot day of sightseeing. It also had a bar area, sun loungers and umbrellas; all with views of roof tops and the cathedral. Inside, the hotel offers plenty of lounges in which to relax and enjoy gentle music, while admiring a comprehensive display of musical instruments. Our room was clean, stocked with goodies and extras, such as slippers, chocolates and complimentary mineral water, and the bed was incredibly comfortable. The only criticism was that our room was quite cramped - but we didn't go to Seville to hang out in our hotel room! Also, the staff were friendly, helpful and professional."

A verified traveler stayed at Hotel Amadeus Sevilla

Hotel Rey Alfonso X

5 out of 5

Posted 4 days ago

Travelocity Verified Review

"The rooms were kept spotlessly clean: Rous and her team were true professionals. I also loved the location of the hotel: Not far from the tren station and within a 4 mile walking distance from everything I wanted to see in Sevilla. The rooftop pool was a great place to beat the 100 F heat and enjoy a cold beverage. The front desk personnel were always friendly and welcoming! Thank you!!! I will always choose to stay here when I visit Sevilla!"

A verified traveler stayed at Hotel Rey Alfonso X