Book Hotels in Santa Cruz

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Cruz hotels

Collections by ULIV Polanco

Collections by ULIV Polanco

4.5 out of 5
568 Calzada General Mariano Escobedo Mexico City
$154 nightly
The price is $184 total per night from Oct 18 to Oct 19
$184 total
Oct 18 - Oct 19
Total with taxes and fees
This aparthotel features a gym and a rooftop terrace. WiFi in public areas is free. Valet parking, a business center, and luggage storage are also offered.
"Un buen hotel para una semana de trabajo"

Reviewed on Oct 16, 2026

Opens in a new windowCollections by ULIV Polanco
Downtown Treasure Place

Downtown Treasure Place

2.5 out of 5
85 Marte Guerrero Mexico City CDMX
Fully refundableReserve now, pay when you stay
$29 nightly
The price is $35 total per night from Oct 22 to Oct 23
$35 total
Oct 22 - Oct 23
Total with taxes and fees
This aparthotel features a gym and a rooftop terrace. There's no skimping on freebies - guests receive free breakfast, free WiFi, and free self parking. A business ...
"This was our first hostel experience, so sharing restrooms and showers was interesting and definitely takes some timing and patience. 😂 The communal areas are modern, artsy and nicely decorated. It really does feel like a “treasure.” The terrace looked great, but unfortunately it rained our entire ..."

Reviewed on Oct 16, 2026

Opens in a new windowDowntown Treasure Place
InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

4 out of 5
Campos Eliseos 218 Mexico City
$439 nightly
The price is $525 total per night from Oct 25 to Oct 26
$525 total
Oct 25 - Oct 26
Total with taxes and fees
A full-service spa, 5 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Opens in a new windowInterContinental Presidente Mexico City by IHG
Casa Olea

Casa Olea

2 out of 5
C. de Francisco Díaz Covarrubias Mexico City CDMX
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $70 total per night from Nov 16 to Nov 17
$70 total
Nov 16 - Nov 17
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. A coffee shop is also provided.
Opens in a new windowCasa Olea
Hyatt Regency Mexico City

Hyatt Regency Mexico City

5 out of 5
Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
$367 nightly
The price is $439 total per night from Nov 15 to Nov 16
$439 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, ...
Opens in a new windowHyatt Regency Mexico City
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 out of 5
Carretera Federal Mexico Pachuca Base Zumpango MEX
Fully refundable
$128 nightly
The price is $153 total per night from Nov 17 to Nov 18
$153 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features 2 restaurants and a gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and free airport shuttle. ...
Opens in a new windowHoliday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
ULIV Parque Lincoln

ULIV Parque Lincoln

3.5 out of 5
40 Enrique Ibsen Polanco III Sección Mexico City CDMX
$137 nightly
The price is $163 total per night from Oct 18 to Oct 19
$163 total
Oct 18 - Oct 19
Total with taxes and fees
This aparthotel features a gym and a rooftop terrace. Traveling on business? Take advantage of the business center and free WiFi in public areas. A picnic area, ...
Opens in a new windowULIV Parque Lincoln
JW Marriott Hotel Mexico City Polanco

JW Marriott Hotel Mexico City Polanco

5 out of 5
Andres Bello No 29 Mexico City
Fully refundableReserve now, pay when you stay
$689 nightly
The price is $823 total per night from Oct 24 to Oct 25
$823 total
Oct 24 - Oct 25
Total with taxes and fees
This luxury hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
Opens in a new windowJW Marriott Hotel Mexico City Polanco
Exe Alameda Reforma

Exe Alameda Reforma

4 out of 5
Av. México-Tenochtitlán 22 Mexico City Mexico City
$62 nightly
The price is $74 total per night from Oct 21 to Oct 22
$74 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowExe Alameda Reforma
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz?
From well-designed amenities to extra room to move, kid-friendly hotels are equipped with features that can help transform a standard family vacation into a fantastic one. These Santa Cruz options make getting away with your youngsters child's play: Your entourage will enjoy their time at Hotel Finca Las Hortensias. Complimentary breakfast and a swimming pool are a few of the things that help make this hotel a favorite. La Morada Tepotzotlan Boutique & Spa is another excellent choice. After a long day of exploring, come back home to your comfy room and amenities like a swimming pool and a sauna.
Where can I find cheap hotels in Santa Cruz?
At Travelocity you'll find really nice hotels in Santa Cruz at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz rather than in Santa Cruz. We may find you even better rates, too.
How do I find the best Santa Cruz hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz?
The cheapest hotel in Santa Cruz is $35. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz?
There are 1,600 hotels in Santa Cruz on Travelocity.
What are the best hotels in Santa Cruz?
Santa Cruz has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz for you!
When is the best time to visit Santa Cruz?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz during February, March and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as June, October and December.
When is the cheapest time to stay in Santa Cruz?
Based on historic data is usually the cheapest month to visit Santa Cruz. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz?
There are multiple hotels in Santa Cruz that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz. We have plenty of kid-friendly hotels in Santa Cruz to choose from on Travelocity!
Why book a hotel in Santa Cruz through Travelocity?
Because we have the top hotels in Santa Cruz! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz hotel reviews by fellow wanderers

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Amazing property, all we're very comfortable, employees very professional"
A verified traveler stayed at Holiday Inn Express Mexico Basilica by IHG
Holiday Inn Express Mexico Basilica by IHG

Explore More Ways to Travel with Travelocity