Book Hotels in Northwest Alabama, AL
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Top Northwest Alabama hotels
Loft in the Heart of Downtown — steps away from Pickett, UNA, Dining, Shops
Florence AL
$289 nightly
The price is $327 total per night from Aug 23 to Aug 24
$327 total
Aug 23 - Aug 24
Total with taxes and fees
This apartment features laundry facilities.
"This loft is great! Just like the pictures, coazy, clean, beautiful windows with an amazing view of downtown, easy walk to all the shops and restaurants. The host was great, check and and check out were a breeze. We stayed here while moving our daughter into the dorms on campus, which is just a few ..."
Reviewed on Aug 17, 2026
Renaissance Shoals Resort & Spa
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
$289 nightly
The price is $332 total per night from Aug 23 to Aug 24
$332 total
Aug 23 - Aug 24
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the free WiFi in public ...
"Very nice hotel. The facility, staff, food, and atmosphere are all top shelf."
Reviewed on Aug 17, 2026
Spark by Hilton Tuscumbia Muscle Shoals
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Sep 13 to Sep 14
$94 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Everything was so clean and the staff were as helpful as could be!"
Reviewed on Aug 16, 2026
Comfort Suites Florence Shoals Area
140 Matthew Paul Ct Florence AL
Fully refundable
$95 nightly
The price is $109 total per night from Sep 20 to Sep 21
$109 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Clean room and comfortable beds. Breakfast was mediocre. Juice machine was out and coffee was watery. Other than breakfast being a bit of a bummer, the stay was great!"
Reviewed on Aug 16, 2026
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Aug 23 to Aug 24
$75 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Todo excelente. El único detalle que los empleados son como mal humorados todos pero se puede manejar"
Reviewed on Aug 16, 2026
Baymont by Wyndham Florence/Muscle Shoals
115 Ana Drive Florence AL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Aug 23 to Aug 24
$87 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
"Room was filthy. Property is in poor shape. This place should be condemned"
Reviewed on Aug 21, 2026
Days Inn by Wyndham Muscle Shoals Florence
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Aug 25 to Aug 26
$83 total
Aug 25 - Aug 26
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
The Stricklin Hotel
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $218 total per night from Aug 23 to Aug 24
$218 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Clarion Inn Sheffield Muscle Shoals
4900 Hatch Blvd Sheffield AL
Fully refundable
$79 nightly
The price is $89 total per night from Aug 23 to Aug 24
$89 total
Aug 23 - Aug 24
Total with taxes and fees
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
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See all available properties in Northwest Alabama
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Northwest Alabama hotels
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E Tuscumbia AL
$67 nightly
The price is $75 total per night from Aug 23 to Aug 24
$75 total
Aug 23 - Aug 24
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Northwest Alabama with star-rating
Check Northwest Alabama Hotels by Star Rating
4 Star Hotels
3 properties
Recent Northwest Alabama hotel reviews by fellow wanderers
Holiday Inn Guin by IHG
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Overall good stay for a fair rate"
A verified traveler stayed at Holiday Inn Guin by IHG
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