Book Hotels in Northwest Alabama, AL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Northwest Alabama hotels

Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa

3.5 out of 5
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $309 total per night from Nov 23 to Nov 24
$309 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the free WiFi in public ...
"Phenomenal hotel! I cannot say enough good things about the incredibly helpful staff, beautiful rooms, cool music decor, top notch pool area, fabulous coffee cafe and lovely grounds. The bar / restaurant, Swampers was awesome. Local music every night. And the rotating restaurant was such a fun treat. ..."

Reviewed on Nov 6, 2026

Opens in a new windowRenaissance Shoals Resort & Spa
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Nov 8 to Nov 9
$79 total
Nov 8 - Nov 9
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
"The sleeping rooms and breakfast room were very nice, looked new and clean. The staff was very friendly and helpful. We'd stay there again if in the area."

Reviewed on Nov 5, 2026

Opens in a new windowDays Inn by Wyndham Muscle Shoals Florence
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Fully refundable
$88 nightly
The price is $101 total per night from Nov 29 to Nov 30
$101 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Good eggs but need more options. Only two juices"

Reviewed on Nov 6, 2026

Opens in a new windowComfort Suites Florence Shoals Area
Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $92 total per night from Nov 15 to Nov 16
$92 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Breakfast was not up to par, they could at least had a waffle appliance, hard boiled eggs didn’t do it for me"

Reviewed on Nov 2, 2026

Opens in a new windowSpark by Hilton Tuscumbia Muscle Shoals
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $185 total per night from Dec 7 to Dec 8
$185 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Opens in a new windowThe Stricklin Hotel
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Fully refundable
$105 nightly
The price is $121 total per night from Nov 22 to Nov 23
$121 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowHoliday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 9 to Nov 10
$70 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Opens in a new windowMicrotel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Days Inn by Wyndham Hamilton

Days Inn by Wyndham Hamilton

2 out of 5
1849 Military St Hamilton AL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $80 total per night from Nov 11 to Nov 12
$80 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowDays Inn by Wyndham Hamilton
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Nov 22 to Nov 23
$78 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
Opens in a new windowBaymont by Wyndham Florence/Muscle Shoals
Don't see what you're looking for?
See all available properties in Northwest Alabama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Northwest Alabama hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Northwest Alabama hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity