Book Hotels in Northwest Alabama, AL

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Nov 8 - Nov 9
Tomorrow
Nov 9 - Nov 10
Next weekend
Nov 14 - Nov 16
In two weeks
Nov 21 - Nov 23

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Northwest Alabama hotels

Holiday Inn Guin by IHG

Holiday Inn Guin by IHG

3 out of 5
5750 Highway 44, Guin, AL
Fully refundable
$122 nightly
The price is $140 total per night from Dec 7 to Dec 8
$140 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The breakfast menu was great with plenty of choices. The restaurant staff were kind and treated us with care.

Reviewed on Oct 21, 2025

Opens in a new windowHoliday Inn Guin by IHG
Renaissance Shoals Resort and Spa

Renaissance Shoals Resort and Spa

3.5 out of 5
10 Hightower Place, Florence, AL
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $286 total per night from Nov 10 to Nov 11
$286 total
Nov 10 - Nov 11
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, express ...
The rooms were updated and clean. The entire staff was very friendly and helpful. This has been our 3rd time staying with this establishment because we enjoy it so much there.

Reviewed on Oct 27, 2025

Opens in a new windowRenaissance Shoals Resort and Spa
The ColdWater Inn

The ColdWater Inn

3.5 out of 5
712 Hwy 72 W, Tuscumbia, AL
$82 nightly
The price is $92 total per night from Nov 11 to Nov 12
$92 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Beautiful hotel and rooms, clean facilities, and good breakfast! Very reasonable prices, and very very reasonable pet fee.

Reviewed on Nov 3, 2025

Opens in a new windowThe ColdWater Inn
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St, Florence, AL
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $218 total per night from Nov 10 to Nov 11
$218 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Everything ok

Reviewed on Nov 3, 2025

Opens in a new windowThe Stricklin Hotel
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct, Florence, AL
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Nov 11 to Nov 12
$123 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Nice place. We stay here whenever we come to Florence Al. Nice location, great staff, fair price, clean rooms and a well kept.

Reviewed on Nov 4, 2025

Opens in a new windowComfort Suites Florence Shoals Area
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave, Muscle Shoals, AL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Nov 17 to Nov 18
$71 total
Nov 17 - Nov 18
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Friendly staff, very clean, comfortable bed. Exactly what we needed, a clean, comfortable place to stay the night. Extremely reasonable price too.

Reviewed on Nov 3, 2025

Opens in a new windowDays Inn by Wyndham Muscle Shoals Florence
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 17 to Nov 18
$70 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great place to stay. Location was an easy drive to all the attractions

Reviewed on Oct 21, 2025

Opens in a new windowMicrotel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd, Sheffield, AL
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Front desk staff was very helpful, polite & welcoming …. Room was also very clean

Reviewed on Oct 26, 2025

Get rates
Opens in a new windowClarion Inn Sheffield Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive, Florence, AL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Nov 10 to Nov 11
$78 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
All good

Reviewed on Nov 2, 2025

Opens in a new windowBaymont by Wyndham Florence/Muscle Shoals
Don't see what you're looking for?
See all available properties in Northwest Alabama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Northwest Alabama hotels

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

1852 Highway 72 E, Tuscumbia, AL
$63 nightly
The price is $70 total per night from Nov 17 to Nov 18
$70 total
Nov 17 - Nov 18
Total with taxes and fees
8/10 Very Good! (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Northwest Alabama hotel reviews by fellow wanderers

Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Nice place. We stay here whenever we come to Florence Al. Nice location, great staff, fair price, clean rooms and a well kept. "
A verified traveler stayed at Comfort Suites Florence Shoals Area
Comfort Suites Florence Shoals Area

Explore More Ways to Travel with Travelocity