Hotels with Room Service in Northwest Alabama from $72
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Top Northwest Alabama Hotels with Room Service

Holiday Inn Guin by IHG
5750 Highway 44 Guin AL
Free Cancellation
$137 nightly
The price is $157 total per night
$157 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Renaissance Shoals Resort and Spa
10 Hightower Place Florence AL
Free Cancellation
Reserve now, pay when you stay
$249 nightly
The price is $286 total per night
$286 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, express ...

Comfort Inn & Suites Tuscumbia - Muscle Shoals
5101 Hwy 43 S Tuscumbia AL
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $119 total per night
$119 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...

Clarion Inn Sheffield Muscle Shoals
4900 Hatch Blvd Sheffield AL
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $72 total per night
$72 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Northwest Alabama hotels essential information
Accommodation | 753 hotels |
|---|---|
Lowest Price | $72 |
Highest Price | $286 |
Popular hotels | Renaissance Shoals Resort and Spa, Comfort Inn & Suites Tuscumbia - Muscle Shoals, Holiday Inn Guin by IHG, Clarion Inn Sheffield Muscle Shoals |
Recent Northwest Alabama hotel reviews by fellow wanderers

Holiday Inn Guin by IHG
5 out of 5
Posted 3 weeks ago
Travelocity Verified Review
"Great stay!"
A verified traveler from Birmingham stayed at Holiday Inn Guin by IHG

Renaissance Shoals Resort and Spa
5 out of 5
Posted 1 month ago
Travelocity Verified Review
"Wonderful experience, check in smooth, staff friendly, room incredible, Muscle Shoals Sound Studio decor very cool. "
A verified traveler stayed at Renaissance Shoals Resort and Spa
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- Flights from Northwest Alabama Regional
- Boutique Air Dallas (DFW) to Muscle Shoals (MSL) flights
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