Book a hotel near Main Street, Massachusetts

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Main Street hotels essential information

Accommodation
5,651 hotels
Lowest Price
$110
Highest Price
$1,082
Popular hotels
The Ocean View, Craigville Beach Compound | 4 Private Suites with a Ocean View!, Craigville Beach Inn, Hyannis Travel Inn, Spacious 4 bedroom PRIVATE HOME centrally located to all the Cape has to offer, Holiday Inn Express Hyannis Cape Cod by IHG, Cozy Cape Cottage, Quiet & Private, Minutes from Beach, Sleeps 8+, 4BD/2BA. Tranquil Cape Getaway for family , Margaritaville Resort Cape Cod, Hyannis Plaza Hotel, Spacious Lake House for Large Groups w Private Acre+ short path to Lake, Hyannis Harbor Hotel

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