Book Hotels in Irene, SD
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Top Irene hotels

Cozy Cabin get away - walking distant to beach
Crofton
This cabin featured laundry facilities and barbecue grills.
"Hosts were great and very helpful. House was clean and had everything we needed. 10/10"
Reviewed on Aug 17, 2025

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $169 total per night from Oct 19 to Oct 20
$169 total
Oct 19 - Oct 20
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"The front desk stuff was nice ! They greeted you when you came in and were very helpful. At same time breakfast was very poor there was almost nothing to eat. The hotel was brand new and looked good and clean. Outside hotel different story it’s build on Parking lot of a shopping center which was ..."
Reviewed on Sep 27, 2025

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave, Yankton, SD
Fully refundable
$104 nightly
The price is $115 total per night from Nov 16 to Nov 17
$115 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Hope was amazing at check in. She did a great job welcoming us."
Reviewed on Oct 6, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Oct 26 to Oct 27
$112 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
"The staff was friendly and helpful, they let us check-in 1 hour early, they were great with kids, the room was clean except for what looked like a juice stain on the carpet. The heat worked great, it was quiet in the room, and the beds were comfortable. Breakfast had many different options, and the ..."
Reviewed on Oct 16, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"nice place"
Reviewed on Oct 11, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Oct 23 to Oct 24
$117 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This was the perfect hotel for my family to stay in for a wedding. We enjoyed the breakfast, pool, and attached restaurant. I would stay there again."
Reviewed on Oct 13, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Oct 20 to Oct 21
$94 total
Oct 20 - Oct 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"The room was excellent, air conditioner kept is cool, the shower had great hot water, the beds were really nice."
Reviewed on Oct 15, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Nov 2 to Nov 3
$85 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"The hotel was clean and quiet"
Reviewed on Oct 6, 2025

Super 8 by Wyndham Beresford
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $70 total per night from Oct 19 to Oct 20
$70 total
Oct 19 - Oct 20
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
"Super 8 needs to bring back eggs, meat and biscuits and gravy"
Reviewed on Oct 12, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Irene hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 23 hours ago
Travelocity Verified Review
"The staff was friendly and helpful, they let us check-in 1 hour early, they were great with kids, the room was clean except for what looked like a juice stain on the carpet. The heat worked great, it was quiet in the room, and the beds were comfortable. Breakfast had many different options, and the area was kept cleaned and stocked. Check-out was simple and easy as well. The hotel is right behind the mall that has hobby lobby, 5 below, and Marshall's, there is a McDonald's a block away and a gas station right up the street. "
A verified traveler stayed at Comfort Inn Yankton SD
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