Book Hotels in Irene, SD
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Top Irene hotels

Gavins Point Lakehouse
Yankton
This vacation home includes a garden and laundry facilities.
Simply Stunning
"Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely ..."
Reviewed on Aug 3, 2025

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $169 total per night from Oct 5 to Oct 6
$169 total
Oct 5 - Oct 6
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"The front desk stuff was nice ! They greeted you when you came in and were very helpful. At same time breakfast was very poor there was almost nothing to eat. The hotel was brand new and looked good and clean. Outside hotel different story it’s build on Parking lot of a shopping center which was ..."
Reviewed on Sep 27, 2025

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave, Yankton, SD
Fully refundable
$123 nightly
The price is $135 total per night from Oct 5 to Oct 6
$135 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Room was clean and comfortable. The breakfast was wonderful had many choices. The staff was pleasant and helpful we would stay there again!"
Reviewed on Sep 22, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Oct 7 to Oct 8
$112 total
Oct 7 - Oct 8
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
Great hotel
"Clean room, great breakfast, great coffee."
Reviewed on Sep 28, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Enjoyed outdoor"
Reviewed on Sep 13, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Oct 5 to Oct 6
$117 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Breakfast was not very good."
Reviewed on Sep 15, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Sep 30 to Oct 1
$94 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"Comfortable, convenient, clean at a affordable price."
Reviewed on Sep 22, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Oct 5 to Oct 6
$90 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Good value"
Reviewed on Sep 22, 2025

Super 8 by Wyndham Beresford
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $68 total per night from Oct 5 to Oct 6
$68 total
Oct 5 - Oct 6
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
"It was ok"
Reviewed on Jul 23, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Irene hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 14 hours ago
Travelocity Verified Review
"Clean room, great breakfast, great coffee. "
A verified traveler stayed at Comfort Inn Yankton SD
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