Book Hotels in Irene, SD
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Top Irene hotels

Gavins Point Lakehouse
Yankton
This vacation home includes a garden and laundry facilities.
Meeting in the Middle
"Gavin’s Point Lakehouse was above and beyond expectations! They really have everything you need and more, from the bigger items to the smallest details. We had family coming from Nebraska and some from South Dakota. It was so great to have such a nice place to call home for the weekend! Highly recommend ..."
Reviewed on Jun 29, 2025

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $169 total per night from Jul 20 to Jul 21
$169 total
Jul 20 - Jul 21
Total includes taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"Everything was good"
Reviewed on Jul 10, 2025

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave, Yankton, SD
Fully refundable
$128 nightly
The price is $141 total per night from Aug 3 to Aug 4
$141 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Loved it!
"The beds are amazing! Pool was perfect! Will definitely stay there again!"
Reviewed on Jul 11, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$134 nightly
The price is $141 total per night from Jul 16 to Jul 17
$141 total
Jul 16 - Jul 17
Total includes taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Beautiful place, rooms are very outdated but at least clean. Very friendly staff and beautiful beaches"
Reviewed on Jul 3, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $132 total per night from Aug 10 to Aug 11
$132 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
"Loved it here. Super safe and great staff."
Reviewed on Jul 7, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Jul 27 to Jul 28
$117 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"It was clean. I had a leak in my room and the help was really nice. Maintenance came and looked into right away."
Reviewed on Jul 7, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $91 total per night from Jul 28 to Jul 29
$91 total
Jul 28 - Jul 29
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Impressive for newly renovated motel
"Overall, it was quite good for the newly renovated motel, which previously resembled a Super 8. Everything is very convenient. Just that the water pressure for the shower might need some gain. :-)"
Reviewed on Jul 7, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $96 total per night from Jul 21 to Jul 22
$96 total
Jul 21 - Jul 22
Total includes taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"The workers were delightful and very friendly. The rooms were adequate. Actually ironically the toilet paper was superb which is a funny way to judge how much a hotel cares about you. But maintenance of the place is very poor. The rugs are disgusting. The pool though indoor wasn't even heated. The ..."
Reviewed on Jun 22, 2025

Super 8 by Wyndham Beresford
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $76 total per night from Jul 29 to Jul 30
$76 total
Jul 29 - Jul 30
Total includes taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
"Very clean, friendly and helpful."
Reviewed on Jun 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Irene hotel reviews by fellow wanderers

Holiday Inn Express & Suites Yankton by IHG
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"The beds are amazing! Pool was perfect! Will definitely stay there again!"
A verified traveler stayed at Holiday Inn Express & Suites Yankton by IHG
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