
Deals on vacations and trips to Santee
Save when you book Santee package deals
Santee flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Sleep Inn Columbia
Price was $599, price is now $541 per person
$541
per person
Sep 23 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Columbia (CAE)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business center, express check-in, and conference space. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.

Cambria Hotel Columbia Downtown The Vista
Downtown Columbia
Price was $845, price is now $759 per person
$759
per person
Sep 23 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Columbia (CAE)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Self parking, a communal living room, and a computer station are also offered.

Country Inn & Suites by Radisson, Columbia Airport, SC
Price was $708, price is now $652 per person
$652
per person
Sep 23 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Columbia (CAE)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like continental breakfast and free self parking.

Tru By Hilton Columbia Greystone
Price was $679, price is now $626 per person
$626
per person
Sep 23 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Columbia (CAE)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's a 24-hour gym on site, and a 24-hour front desk and a snack bar/deli are also provided.

Homewood Suites by Hilton Columbia
Price was $683, price is now $629 per person
$629
per person
Sep 23 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Columbia (CAE)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Top Santee hotels deals

Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly

Tru By Hilton Santee
263 Britain St. and 273 Britain St., Santee, SC
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $112 total per night
$112 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $144 total per night
$144 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.
Pool
Breakfast included

Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $111 total per night
$111 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.
Pool
Breakfast included

Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$132 nightly
The price is $147 total per night
$147 total
Aug 27 - Aug 28
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.
Pool
Breakfast included

Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Free Cancellation
$122 nightly
The price is $135 total per night
$135 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and perks like free self parking.
Pool
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Santee State Park
4/5(43 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.
Santee Cooper Country Club
4/5(12 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.
Santee National Golf Club
3.5/5(19 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.
Frequently asked questions
Photos of local treasures
Browse Santee vacation photos for more inspiration

Top all inclusive vacation packages with airfare
Book a vacation to Santee
Most popular
Hotels
- Cheap Hotels in Columbia
- Cheap Hotels in Pawleys Island
- Cheap Hotels in Myrtle Beach
- Myrtle Beach Pet Friendly Hotels
- Myrtle Beach Beach Resorts & Hotels
- Cheap Hotels in Summerville
- Cheap Hotels in Charleston
- Myrtle Beach All Inclusive Resorts & Hotels
- North Myrtle Beach Beach Resorts & Hotels
- Cheap Hotels in Surfside Beach
- Cheap Hotels in Murrells Inlet
- Hilton Head Island Beach Resorts & Hotels
- Cheap Hotels in Conway
- Cheap Hotels in Greenville
- Cheap Hotels in Hilton Head Island
- Cheap Hotels in North Myrtle Beach
- Cheap Hotels in North Charleston
- Charleston Beach Resorts & Hotels
- Cheap Hotels in Rock Hill
Cars
Activities