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See all 239 cruises to South America

Cruises to South America

What’s there to see at the top South American cruise destinations?

  • Unique Wildlife: If you’ve always wanted to see a penguin up close, then both Punta Arenas and the Falkland Islands have these well-dressed birds roaming the surrounding beaches, as well as elephant seals and Commerson’s dolphins. Beyond the wildlife, both areas boast unspoiled majestic beauty. Off the coast of Ecuador, the Galapagos Islands are also worth a look. Besides the famed giant tortoises, the rich marine life (including sea iguanas) surrounding the islands is a must-see for any diver.
  • One-of-a Kind Cities: Experience the natural and cultural diversity of South America. A port of call in Buenos Aires introduces you to a city of old-world European charm fused with a vibrant Latin culture and an incredible food scene famous for succulent steaks. Rio de Janeiro’s golden beaches and lush mountains frame a city brimming with activity day and night. Once you round Cape Horn, you may stop in Tierra del Fuego. The town of Ushuaia offers travelers a welcoming basecamp to recharge after they have explored these windswept lands at world’s end.

Which South America cruise line is right for me? 

  • MSC Cruises: This Swiss-based cruise line strives for a more refined cruising experience. You won’t find a lot of glitz on these ships, but simple elegance and eclectic amenities like adults-only pools, as well as spas and 4D cinemas. While the line doesn’t specifically cater to kids, those that are 11 years and younger sail for free.
  • CostaThe largest cruise line in Europe offers an Italian-style experience: the food, shows, décor, and festive atmosphere are Mediterranean-inspired. This line aims to give passengers a memorable experience off the ship as well, and provides numerous shore excursions.
  • Princess Cruises: This line caters to families and couples seeking a competitively priced and relaxed cruise. They have supervised activities for children like science centers and movie nights, and offer both assigned and unassigned dining experiences.

Cheap Flights

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap Hotels

Rochester Classic

Rochester Classic

Esmeralda 542, Buenos Aires, Capital Federal
    3.5 out of 5.0

    Located in Microcentro, this hotel is within a 10-minute walk of Florida Street, Teatro Colon, and Obelisco. Galerias Pacifico and Buenos Aires Metropolitan ...

    Rochester ClassicGet Rates

    Regal Pacific Buenos Aires

    Regal Pacific Buenos Aires

    25 De Mayo, 764, Buenos Aires, Capital Federal
      4.5 out of 5.0

      Located in Microcentro, this luxury hotel is within a 5-minute walk of Galerias Pacifico and Florida Street. Centro Cultural Kirchner and Casa Rosada are also ...

      Regal Pacific Buenos Aires$99

      Almacruz Hotel y Centro de Convenciones (Ex Galerías)

      Almacruz Hotel y Centro de Convenciones (Ex Galerías)

      San Antonio 65, Santiago, Region Metropolitana
        4.0 out of 5.0

        Located in Downtown Santiago, this hotel is within a 10-minute walk of San Francisco Church and Plaza de Armas. Clinica Santa Maria and Movistar Arena are also ...

        Almacruz Hotel y Centro de Convenciones (Ex Galerías)Get Rates

        Argentina Tango Hotel

        Argentina Tango Hotel

        Suipacha 545, Buenos Aires, Capital Federal
          3.0 out of 5.0

          Located in Microcentro, this hotel is within a 5-minute walk of Lavalle Street, Teatro Colon, and Obelisco. Florida Street and Galerias Pacifico are also within ...

          Argentina Tango Hotel$38

          *Prices are cruise only, per person, double occupancy. Taxes, fees and port expenses not included. Rates are valid for US and Canadian residents only. Fuel supplement may apply. Savings advertised and Expedia Extras are based on specific cabin types and sailing dates, and may not be available for all cabin types/sailings.