Cheap Flights to Upstate South Carolina from $64

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

How Much Does it Cost To Fly To Upstate South Carolina?

The cheapest prices found with in the last 7 days for return flights were $127 and $64 for one-way flights to Upstate South Carolina for the period specified. Prices and availability are subject to change. Additional terms apply

Mon, May 25 - Sun, May 31
MSP
Minneapolis - St. Paul Intl.
AVL
Asheville Regional
$127 Roundtrip, found 19 hours ago
$127
Roundtrip
found 19 hours ago
Select Sun Country Airlines flight, departing Mon, May 25 from Minneapolis - St. Paul Intl. to Asheville Regional, returning Sun, May 31, priced at $127 found 19 hours ago
OriginDestinationTravel DatesFlights From*
DCAGreerMay 19 to May 20$133
ORDGreerApril 7 to April 10$177
BOSFletcherMay 9 to May 16$179
EWRGreerApril 4 to April 8$205
EWRGreerApril 4 to April 8$205
LGAFletcherMay 13 to May 23$221
LGAFletcherMay 13 to May 23$221
LGAGreerApril 16 to April 18$227
RFDFletcherMay 13 to May 19$228
EWRFletcherMay 16 to May 20$231
BOSGreerApril 8 to April 15$241
IAHGreerApril 16 to May 2$249
IAHFletcherApril 17 to April 21$266
DCAFletcherApril 7 to April 11$342
DALGreerMay 4 to May 8$379
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCAGreerMarch 14 to March 16$304
IAHGreerMarch 13 to March 23$332
BOSFletcherMarch 15 to March 28$337
EWRGreerMarch 13 to March 15$352
LGAGreerMarch 15 to March 18$359
JFKFletcherMarch 14 to March 27$368
IAHFletcherMarch 13 to March 17$378
LGAFletcherMarch 13 to March 15$400
EWRFletcherMarch 13 to March 16$425
DCAFletcherMarch 14 to March 16$443
PHLGreerMarch 14 to March 20$489
PHLFletcherMarch 15 to March 16$498
DALGreerMarch 13 to March 21$519
MDWFletcherMarch 13 to March 19$520
DFWFletcherMarch 14 to March 24$573
*Prices include taxes and fees

Upstate South Carolina Flight Information

Traveling to
Upstate South Carolina
Lowest Price
$127
Number of Airlines Serving
Airlines Serving
Sun Country Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Upstate South Carolina Accommodation Deals

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 out of 5
128 Interstate Blvd Anderson SC
$55 nightly
The price is $61 total per night from Mar 22 to Mar 23
$61 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (857 reviews)
Very comfortable and clean

Reviewed on Mar 3, 2026

Opens in a new windowBaymont by Wyndham Anderson Clemson
Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

2 out of 5
60 Roper Mountain Rd Greenville SC
$65 nightly
The price is $71 total per night from Mar 12 to Mar 13
$71 total
Mar 12 - Mar 13
Total with taxes and fees
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (1,003 reviews)
Checking in was fine and the person behind the counter was nice but the rooms were filled with smell of cigarettes and other types of smoke and bugs. I did not feel comfortable or safe. Several people loitering around the parking lot.

Reviewed on Mar 8, 2026

Opens in a new windowDays Inn by Wyndham Greenville
Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

2.5 out of 5
31 Old Country Rd Greenville SC
$64 nightly
The price is $70 total per night from Mar 15 to Mar 16
$70 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (1,009 reviews)
It was ok room was a little out dated and I asked for a double for 2 adults and I got that but with a crib but it was a great room bed were soft water was hot but tv was acting up but it wasn't a bad stat

Reviewed on Mar 9, 2026

Opens in a new windowBaymont by Wyndham Greenville Woodruff Rd
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Red Roof Inn Spartanburg – I-26

Red Roof Inn Spartanburg – I-26

2 out of 5
6765 Pottery Rd Spartanburg SC
$61 nightly
The price is $67 total per night from Mar 24 to Mar 25
$67 total
Mar 24 - Mar 25
Total with taxes and fees
Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions County University Soccer Stadium and Susan Jacobs Arboretum ...
7/10 Good! (752 reviews)
Almost perfect. Everyone was very nice and friendly and helpful. The refrigerator in the room had stuff spilled in it that we had to clean before using it. There was nothing in the soap, shampoo, conditioner and lotion bottles. Fortunately I had those things in my luggage and the guy at the front ...

Reviewed on Feb 15, 2026

Opens in a new windowRed Roof Inn Spartanburg – I-26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Upstate South Carolina with Airport Shuttles

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
$72 nightly
The price is $79 total per night from Mar 10 to Mar 11
$79 total
Mar 10 - Mar 11
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,003 reviews)
N/A

Reviewed on Mar 9, 2026

Opens in a new windowBest Western Greenville Airport Inn
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
$117 nightly
The price is $129 total per night from Mar 15 to Mar 16
$129 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (646 reviews)
The rooms were very quiet. The only "gripe" I have is the way to control the heat/air conditioning isn't on the wall. Other than that, it was a great stay. Very comfortable and cozy.

Reviewed on Mar 3, 2026

Opens in a new windowCourtyard Greenville-Spartanburg by Marriott
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
$101 nightly
The price is $111 total per night from Mar 15 to Mar 16
$111 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.6/10 Excellent! (1,021 reviews)
AC unit was very loud, so did not sleep much

Reviewed on Mar 9, 2026

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
$107 nightly
The price is $118 total per night from Apr 5 to Apr 6
$118 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,109 reviews)
Very comfortable accommodations in a great location. Free breakfast and happy hour beverages was a nice touch. Indoor pool on location but not heated. Overall, great stay!!!

Reviewed on Mar 9, 2026

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Upstate South Carolina

The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
$189 nightly
The price is $208 total per night from Mar 15 to Mar 16
$208 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,002 reviews)
I think the

Reviewed on Mar 4, 2026

Opens in a new windowThe Westin Poinsett Greenville
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
$149 nightly
The price is $163 total per night from Mar 22 to Mar 23
$163 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,006 reviews)
Great room, good price, nice staff.

Reviewed on Mar 1, 2026

Opens in a new windowHyatt Regency Greenville
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

2.5 out of 5
231 N Pleasantburg Dr Greenville SC
$74 nightly
The price is $82 total per night from Apr 5 to Apr 6
$82 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (1,005 reviews)
Friendly front desk staff. Room was made up every day with clean towels provided as well.

Reviewed on Mar 4, 2026

Opens in a new windowSleep Inn at Greenville Convention Cente
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
The Bleckley Inn

The Bleckley Inn

3.5 out of 5
151 E Church St Anderson SC
$247 nightly
The price is $274 total per night from Mar 17 to Mar 18
$274 total
Mar 17 - Mar 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free parking, a rooftop terrace, and a fitness center. Popular attractions Church Street Heritage ...
9.8/10 Exceptional! (410 reviews)
Wonderful staff and the room was clean. Hotel is absolutely beautiful

Reviewed on Feb 7, 2026

Opens in a new windowThe Bleckley Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Upstate South Carolina

Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 out of 5
250 Riverplace Greenville SC
$163 nightly
The price is $180 total per night from Mar 15 to Mar 16
$180 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the bar and the helpful staff ...
9.2/10 Wonderful! (1,007 reviews)
I was booked a room And when I arrived they told me they’ve been moved my reservation to springhill suites The ac unit was so loud like I’m on the airplane and I didn’t take any sleep all night room 343

Reviewed on Mar 8, 2026

Opens in a new windowEmbassy Suites by Hilton Greenville Downtown Riverplace
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
$72 nightly
The price is $79 total per night from Mar 10 to Mar 11
$79 total
Mar 10 - Mar 11
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,003 reviews)
N/A

Reviewed on Mar 9, 2026

Opens in a new windowBest Western Greenville Airport Inn
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
$107 nightly
The price is $118 total per night from Apr 5 to Apr 6
$118 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,109 reviews)
Very comfortable accommodations in a great location. Free breakfast and happy hour beverages was a nice touch. Indoor pool on location but not heated. Overall, great stay!!!

Reviewed on Mar 9, 2026

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

2.5 out of 5
116 Interstate Blvd Anderson SC
$105 nightly
The price is $117 total per night from Apr 5 to Apr 6
$117 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,003 reviews)
The rooms were disgusting!! From pee on the toilet seat, to toenails in the carpet, trash laying around the room, stained bed covers & hair in the sheets!!!

Reviewed on Feb 28, 2026

Opens in a new windowCountry Inn & Suites by Radisson, Anderson, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Special

  • 3 people
  • Unlimited mileage
Greenville, South Carolina, USA

$36

$160 total
found 6 days ago
Special undefined

Compact

  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA

$36

$160 total
found 6 days ago
Compact undefined

Economy

  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA

$36

$160 total
found 6 days ago
Economy undefined

Midsize

  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA

$37

$164 total
found 6 days ago
Midsize undefined
Lowest prices found within the past 6 days. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Upstate South Carolina?
To give you a figure to work with, the cheapest roundtrip flight to Upstate South Carolina cost $127 within the last seven days. A good way to grab a travel bargain is to be flexible with your dates. This price was available on Travelocity for flights to Upstate South Carolina departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Upstate South Carolina?
For your greatest chance at securing an excellent flight deal, time your break sometime in May. Based on Travelocity's direct flight demand from January to December last year, it's the cheapest time to fly to Upstate South Carolina.
How can I check my flight status to Upstate South Carolina?
There are a couple of helpful ways to look up your flight status. You'll discover all the important information in our "Trips" portal, which is located at the top right of our homepage. Sign in or create a new account in seconds — you can then view and manage your bookings whenever you need. If you're already on the go, the Travelocity app can also help you look up the status of your flight to Upstate South Carolina, as well as share details with any members of your family flying with you.
How do I find the best deals on flights to Upstate South Carolina?
It's always good to book early, and if possible, avoid flying during the busy tourist season. Another great way to save is by hitting the "Flexible dates" box at the top of the page after searching for your flights. This will reveal ticket prices for nearby days. In the last seven days, the best price for a return flight to Upstate South Carolina was $127. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Upstate South Carolina with Travelocity?
Look for cheap flights to Upstate South Carolina with Travelocity and start arranging your next vacation. With round-the-clock customer service throughout your trip and our Price Match Guarantee, we take the bother out of booking cheap family flights, hotels, experiences and more. Snag a superb deal today and prepare yourself for the adventure of your dreams.
What are the most popular flight routes to Upstate South Carolina?
To help you find great flights to Upstate South Carolina, here's our list of some of the busiest routes:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 3,046 flights a month.
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2,530 flights a month.
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2,166 flights a month.

How much is a flight to Upstate South Carolina on average?
Passengers have picked up roundtrip flights to Upstate South Carolina for between $127 and $573 with Travelocity in the last seven days. Whether you're planning to fly economy or business class, we'll help you get an incredible deal. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
How long is the average flight to Upstate South Carolina?
The length of a direct flight to Upstate South Carolina of course differs, but here you'll find the average travel times for a few preferred routes:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 23 minutes
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 8 minutes
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 2 minutes

What can I expect on a flight to Upstate South Carolina?
If you're about to jump on a long-haul flight to Upstate South Carolina, you can typically expect drinks, meals and entertainment on board. Airlines endeavor to make longer flights as pleasant as possible. Brief journeys — as well as flights with low-cost airlines — may not come with such inclusions. If you're after cheap flights for family vacations with a budget carrier, you should be prepared to pay extra for snacks, drinks and entertainment.

Plane Tickets To Upstate South Carolina

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Upstate South Carolina. Browse through our inventory to explore a wide range of cheap flights to Upstate South Carolina to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Upstate South Carolina as you anxiously await to exit the plane and explore what Upstate South Carolina has to offer. Considering all the amazing local food and culture in Upstate South Carolina, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Upstate South Carolina to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Upstate South Carolina without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Upstate South Carolina with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Upstate South Carolina today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.