Explore 51 Luxury Hotels in Central San Diego

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Best Luxury Hotels in Central San Diego

Kings Inn San Diego

Kings Inn San Diego

1333 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from Nov 9 to Nov 10
$125 total
Nov 9 - Nov 10
Total with taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
8.8/10 Excellent! (3,828 reviews)
"We had a great stay at this hotel! The room was clean, spacious, and very comfortable. The location was also convenient, with food service and a restaurant right downstairs. Overall, we really enjoyed our stay and would definitely recommend it!"

Reviewed on Nov 4, 2026

Opens in a new windowKings Inn San Diego
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

1201 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Dec 3 to Dec 4
$103 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the hot tub and perks like free WiFi. A coffee shop, a snack bar/deli, and a picnic ...
8.2/10 Very Good! (1,906 reviews)
"The bathroom was clean, the wood floor is a plus ( can’t stand hotels with dirty Capet). The one king room was spacious and perfect. Would definitely stay again. Highly recommend."

Reviewed on Nov 3, 2026

Opens in a new windowThe Atwood Hotel San Diego - SeaWorld/Zoo
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Nov 17 to Nov 18
$92 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
8/10 Very Good! (3,163 reviews)
"Place was located in a decent spot. The staff members at the front desk were nice. Only issues were the bathroom door is a sliding door and kept getting stuck and was difficult to open at times. Also the sink is located outside the bathroom which was different. Nothing necessarily special about the ..."

Reviewed on Nov 4, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle

445 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Nov 5 to Nov 6
$97 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast and free WiFi. Business travelers can take advantage of the business center. Self ...
7.2/10 Good! (1,179 reviews)
"The property has had a renovation, and it shows. Nicer than it was several years ago."

Reviewed on Nov 2, 2026

Opens in a new windowSuper 8 by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Nov 5 to Nov 6
$97 total
Nov 5 - Nov 6
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
Opens in a new windowBest Western Seven Seas
Pleasant Inn

Pleasant Inn

5550 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Nov 26 to Nov 27
$102 total
Nov 26 - Nov 27
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. Luggage storage and a safe deposit box are ...
Opens in a new windowPleasant Inn
Hyatt Regency La Jolla

Hyatt Regency La Jolla

3777 La Jolla Village Drive San Diego CA
$244 nightly
The price is $280 total per night from Nov 7 to Nov 8
$280 total
Nov 7 - Nov 8
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Opens in a new windowHyatt Regency La Jolla
Old Town Western Inn & Suites

Old Town Western Inn & Suites

3889 Arista St San Diego CA
Fully refundable
$115 nightly
The price is $130 total per night from Nov 9 to Nov 10
$130 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...
Opens in a new windowOld Town Western Inn & Suites
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More 4 star hotels in Central San Diego

Central San Diego Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Central San Diego luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Central San Diego to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Central San Diego will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Central San Diego, and plan your next opulent escape.


Central San Diego hotels essential information

Accommodation
1,676 hotels
Lowest Price
$92
Highest Price
$309
Popular hotels
Best Western Seven Seas, Kings Inn San Diego, Days Inn by Wyndham San Diego Hotel Circle, Pleasant Inn, Hyatt Regency La Jolla, The Atwood Hotel San Diego - SeaWorld/Zoo, Super 8 by Wyndham San Diego Hotel Circle, Old Town Western Inn & Suites

Popular Luxury Stays in Central San Diego

Recent Central San Diego Hotel Reviews By Fellow Wanderers