Photo by Hitesh Aggarwal
Book a hotel near Casa Santo Domingo Museum, Barrio de La Concepción
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Top hotels close to Casa Santo Domingo Museum

Hotel Museo Spa Casa Santo Domingo
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
$248 nightly
The price is $303 total per night
$303 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public areas. You'll appreciate the gym, poolside bar, and laundry facilities.
Pool
Spa

Las Camelias Inn
3a Calle Oriente no19 Antigua Guatemala Sacatepequez
0.18 mi from Casa Santo Domingo Museum
$95 nightly
The price is $116 total per night
$116 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
An area shuttle and a shopping center shuttle are available at this hotel, along with a rooftop terrace. WiFi in public areas is free. A garden, a snack bar/deli, and a communal living room are also on offer.
Spa
Pet friendly

Casa Santa Rosa Hotel Boutique
1a Calle Oriente No.11 Alameda Antigua Guatemala Sacatepequez
0.23 mi from Casa Santo Domingo Museum
$128 nightly
The price is $156 total per night
$156 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Families will appreciate the onsite laundry facilities and babysitting. A garden, luggage storage, and concierge services are also on offer.
Breakfast included
Parking included

Good Hotel Antigua
Calle del Hermano Pedro No. 12 Antigua Guatemala Sacatepéeuez
Free Cancellation
Reserve now, pay when you stay
0.24 mi from Casa Santo Domingo Museum
$165 nightly
The price is $201 total per night
$201 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A terrace, a garden, and a snack bar/deli are also on offer.
Free WiFi
Restaurant

El Convento Boutique Hotel
2a Avenida Norte No. 11 Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.26 mi from Casa Santo Domingo Museum
$171 nightly
The price is $205 total per night
$205 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, a garden, and a communal living room are also on offer.
Pool
Parking included

El Carmen Hotel
3a. Avenida Norte #9 Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.29 mi from Casa Santo Domingo Museum
$113 nightly
The price is $138 total per night
$138 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel features a restaurant, a rooftop terrace, and a bar/lounge. There's no skimping on freebies - guests receive free cooked-to-order breakfast, free WiFi, and free self parking. A coffee shop, a terrace, and a garden are also on offer.
Breakfast included
Spa

Hotel Posada de Don Rodrigo Antigua
5 Avenida Norte No.17 Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.42 mi from Casa Santo Domingo Museum
$166 nightly
The price is $206 total per night
$206 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A terrace, a garden, and a computer station are also on offer.
Free WiFi
Restaurant

Los Pasos Boutique Hotel & Spa
9 Calle Oriente No. 19 Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.45 mi from Casa Santo Domingo Museum
$133 nightly
The price is $166 total per night
$166 total
Dec 14 - Dec 15
Total with taxes and fees
This luxury hotel features a full-service spa and a restaurant. Enjoy the a rooftop terrace and free perks like cooked-to-order breakfast and WiFi in public areas. A bar/lounge, a 24-hour front desk, and a terrace are also provided.
Breakfast included
Spa

Porta Hotel Antigua
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.52 mi from Casa Santo Domingo Museum
$185 nightly
The price is $226 total per night
$226 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and perks like free self parking.
Pool
Spa

Hotel Camino Real Antigua
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.64 mi from Casa Santo Domingo Museum
$221 nightly
The price is $270 total per night
$270 total
Dec 14 - Dec 15
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this Colonial hotel. Families will appreciate the onsite laundry facilities and in-room childcare. Enjoy the gym and perks like free self parking and free WiFi.
Hot Tub
Spa

Nico Hotel
Avenida El Desengaño Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.72 mi from Casa Santo Domingo Museum
$59 nightly
The price is $71 total per night
$71 total
Dec 17 - Dec 18
Total with taxes and fees
A hot tub is featured at this hotel, along with a coffee shop and free WiFi in public areas. Enjoy the free local cuisine breakfast each morning. A garden is provided and the front desk is staffed around-the-clock.
Hot Tub
Breakfast included

Hotel Soleil La Antigua
9 Calle Poniente Antigua Guatemala Sacatepequez
Free Cancellation
Reserve now, pay when you stay
0.96 mi from Casa Santo Domingo Museum
This hotel's full-service spa, 3 outdoor pools, and 2 hot tubs are some of the highlights. There's fun for all ages with a free kid's club and a children's pool, and barbecue grills are available on site. Enjoy a meal in one of the 2 coffee shops/cafes and free perks like free self parking and a theme park shuttle.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Casa Santo Domingo Museum
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Casa Santo Domingo Museum hotels essential information
Accommodation | 744 hotels |
|---|---|
Lowest Price | $71 |
Highest Price | $303 |
Popular hotels | Hotel Museo Spa Casa Santo Domingo, Porta Hotel Antigua, Hotel Camino Real Antigua, El Carmen Hotel, El Convento Boutique Hotel, Las Camelias Inn, Good Hotel Antigua, Hotel Posada de Don Rodrigo Antigua, Casa Santa Rosa Hotel Boutique, Hotel Soleil La Antigua, Nico Hotel, Los Pasos Boutique Hotel & Spa |
Recent Casa Santo Domingo Museum hotel reviews by fellow wanderers

Hotel Camino Real Antigua
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Amazing hotel with beautiful gardens, great rooms, helpful staff and the top breakfast in Antigua. "
A verified traveler stayed at Hotel Camino Real Antigua
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