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Hotel Museo Spa Casa Santo Domingo

4.5 star property
4.5-star luxury hotel near Casa Santo Domingo Museum

Choose dates to view prices

Photo gallery for Hotel Museo Spa Casa Santo Domingo

Interior entrance
Creator video - submitted by Sallytrubella Travel Shop
Couples treatment rooms, sauna, hot tub, body treatments, aromatherapy
View from property
Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | Jetted tub

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi

Explore the area

View in a map
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez, 3001
  • Place, Casa Santo Domingo Museum
    ‪1 min walk‬
  • Place, Central Park
    ‪6 min walk‬
  • Place, Antigua Guatemala Cathedral
    ‪8 min walk‬
  • Airport, Guatemala City (GUA-La Aurora Intl.)
    ‪53 min drive‬

Room options

View all photos for Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Spa Living (All rooms are different)

Standard Spa Living (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Spa Living (All rooms are different)

9.2 out of 10
Wonderful
(11 reviews)
  • Sleeps 2
  • 2 Double Beds

View all photos for Superior Suite Spa Living (All rooms are different)

Superior Suite Spa Living (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite Spa Living (All rooms are different)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room (All rooms are different)

Standard Room (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Room (All rooms are different)

9.0 out of 10
Wonderful
(33 reviews)
  • Garden view
  • 204 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite (All rooms are different)

Executive Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Executive Suite (All rooms are different)

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Exclusive Suite, 1 King Bed (All rooms are different)

Exclusive Suite, 1 King Bed (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Exclusive Suite, 1 King Bed (All rooms are different)

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite, 1 King Bed (All rooms are different)

Executive Suite, 1 King Bed (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Executive Suite, 1 King Bed (All rooms are different)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite (All rooms are different) (2 adults, 2 children)

Junior Suite (All rooms are different) (2 adults, 2 children) | Premium bedding, minibar, in-room safe, iron/ironing board

Junior Suite (All rooms are different) (2 adults, 2 children)

9.6 out of 10
Exceptional
(4 reviews)
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Suite (All rooms are different)

Deluxe Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Deluxe Suite (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)
  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite (All rooms are different)

Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Suite (All rooms are different)

10.0 out of 10
Exceptional
(3 reviews)
  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 Double Bed

View all photos for Superior Suite, Jetted Tub (All rooms are different)

Superior Suite, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite, Jetted Tub (All rooms are different)

9.4 out of 10
Exceptional
(3 reviews)
  • Sleeps 4
  • 2 Double Beds

About the neighborhood

Antigua Guatemala

Barrio de La Concepción stay.A stay at this Barrio de La Concepción hotel places you steps from Casa Santo Domingo Museum and within a 10-minute walk of Central Park. Iglesia y Convento de Santo Domingo and Jade Maya Factory and Museum are also within half a mile (1 km).

What's nearby

  • Casa Santo Domingo Museum - 1 min walk - 0.0 miles
  • Las Capuchinas Convent - 5 min walk - 0.3 miles
  • Central Park - 6 min walk - 0.4 miles
  • Santa Catalina Arch - 8 min walk - 0.5 miles
  • Antigua Guatemala Cathedral - 8 min walk - 0.5 miles

Getting around

  • La Aurora Intl. Airport (GUA) - 68 min drive

Restaurants

  • ‪7 Caldos Antigua Guatemala - ‬1 min walk
  • ‪Mistico Bar Bistro - ‬4 min walk
  • ‪El Patio de Clio’s - ‬4 min walk
  • ‪Café No Sé - ‬6 min walk
  • ‪Cafe Sol - ‬1 min walk

About this property

Hotel Museo Spa Casa Santo Domingo

4.5-star luxury hotel near Casa Santo Domingo Museum
Hotel Museo Spa Casa Santo Domingo offers its guests a full-service spa, an outdoor pool, and a health club. There are 2 restaurants on site. You can enjoy a drink at one of the bars, which include 2 bars/lounges and a poolside bar. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. A sauna, a terrace, and tour/ticket assistance are also featured at the luxury Hotel Museo Spa Casa Santo Domingo. An airport shuttle (available 24 hours) is available for a fee. Self parking is free.

This 4.5-star Antigua Guatemala hotel is smoke free.

  • 1 building
  • 132 guestrooms or units
  • 2 levels
  • 2 dining venues
  • 2 bars or lounges
  • Meeting rooms
  • Built in 1989
  • Charging station for electric cars
  • Business facilities
  • Conference space
  • Breakfast available (surcharge)
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Tour and ticket information
  • Concierge
  • Terrace
  • Garden
  • Beauty salon
  • Newspapers in lobby (free)
  • ATM
  • No smoking on site
  • Water dispenser
  • Bar by the pool
Hotel Museo Spa Casa Santo Domingo offers 132 air-conditioned accommodations with fireplaces and minibars. Beds feature premium bedding. A pillow menu is available. 42-inch Smart televisions come with premium cable channels.

Bathrooms include bathtubs or showers and hair dryers. Business-friendly amenities include safes and phones. Housekeeping is provided daily.

The onsite spa has couples treatment room(s). Services include facials, body wraps, body scrubs, and body treatments. A variety of treatment therapies are provided, including aromatherapy. The spa is equipped with a sauna and a hot tub.

The spa is open daily. Guests under 18 years old are not allowed in the spa.

Property amenities

Family friendly

  • Crib (surcharge)
  • Laundry facilities
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Internet

  • Available in some public areas: Free WiFi

Parking and transportation

  • Electric car charging station on site
  • 24-hour roundtrip airport shuttle (surcharge)
  • Free self parking on site
  • Wheelchair-accessible parking available
  • Onsite parking includes off-street options

Food and drink

  • Daily full breakfast available 7:00 AM to 11:00 AM for a fee: USD 20 per person
  • 2 bars/lounges
  • 2 restaurants
  • A poolside bar

Things to do

  • Full-service spa
  • Health club
  • Outdoor pool
  • Sauna
  • Steam room
  • Ziplining

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • No elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant

Room amenities

Entertainment

  • 42-inch smart TV with premium cable channels

Bedroom

  • Crib (surcharge)
  • Pillow menu
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Private bathroom
  • Towels provided

Food and drink

  • Limited room service
  • Minibar
  • Restaurant dining guides

More

  • Air conditioning
  • Connecting rooms available
  • Fireplace
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 18

Check-out

Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 61 per pet, per night
  • Only dogs are allowed
  • Maximum 1 (weight limit: 25 lbs per pet)
  • Pets cannot be left unattended
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are available for USD 48.8 per day.
  • Cribs (infant beds) are available for USD 9.76 per day.

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for full breakfast: approximately USD 20 per person
  • Airport shuttle fee: USD 60 per person (one-way)
  • Pet fee: USD 61 per pet, per night
  • Late check-out is available for a fee (subject to availability)
  • Crib (infant bed) fee: USD 9.76 per day
  • Rollaway bed fee: USD 48.8 per day

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and cash
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
This property uses a grey water recycling system
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A credit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, and cash. This property reserves the right to pre-authorize the guest's credit card prior to arrival. This property uses a grey water recycling system. For guests' safety, the property includes a fire extinguisher, a smoke detector, and a first aid kit in each accommodation.

This property charges a fee of USD 45 per night for use of the sofabed.

We should mention

  • Reservations are needed for massage services and spa treatments. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).

Property is also known as

Casa Domingo
Casa Hotel Santo Domingo
Casa Santo Domingo
Casa Santo Domingo Antigua Guatemala
Casa Santo Domingo Hotel
Hotel Casa Domingo
Hotel Casa Santo Domingo Antigua Guatemala
Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo Hotel
Hotel Museo Spa Casa Santo Domingo Antigua Guatemala
Hotel Museo Spa Casa Santo Domingo Hotel Antigua Guatemala

Frequently asked questions

How close is Hotel Museo Spa Casa Santo Domingo to the airport?

Hotel Museo Spa Casa Santo Domingo is 24.8 mi (68-min drive) away from the La Aurora Intl. Airport (GUA) airport, the closest popular airport to the property.

How much does it cost to stay at Hotel Museo Spa Casa Santo Domingo?

As of Feb 23, 2026, prices found for a 1-night stay for 2 adults at Hotel Museo Spa Casa Santo Domingo on Feb 25, 2026 start from $266.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Hotel Museo Spa Casa Santo Domingo have an airport shuttle?

Hotel Museo Spa Casa Santo Domingo offers an airport shuttle 24 hours a day, for a charge of USD 60 per person, one-way.

Does Hotel Museo Spa Casa Santo Domingo offer free breakfast?

Free breakfast isn’t provided at Hotel Museo Spa Casa Santo Domingo, but full breakfast is offered for a fee of USD 20 per person. It's available every day from 7:00 AM to 11 AM.

Is there a casino at Hotel Museo Spa Casa Santo Domingo?

No, there is no casino at this hotel.

What time is check-in at Hotel Museo Spa Casa Santo Domingo?

Check-in start time: 3:00 PM; Check-in end time: midnight.

Is there free parking at Hotel Museo Spa Casa Santo Domingo?

This hotel offers free self parking.

Does Hotel Museo Spa Casa Santo Domingo have a pool?

Hotel Museo Spa Casa Santo Domingo features an outdoor pool.

Does Hotel Museo Spa Casa Santo Domingo have a restaurant?

There are 2 onsite restaurants, offering options like Fusion cuisine and garden views.

Does Hotel Museo Spa Casa Santo Domingo have a spa?

This hotel has a spa, which features body treatments, mani/pedis, and body wraps.

How close is Hotel Museo Spa Casa Santo Domingo to downtown Antigua Guatemala?

Hotel Museo Spa Casa Santo Domingo is 0.4 mi away from Antigua Guatemala.

Hotel Museo Spa Casa Santo Domingo Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 818 out of 1046 reviews
Rating 8 - Good. 118 out of 1046 reviews
Rating 6 - Okay. 51 out of 1046 reviews
Rating 4 - Poor. 30 out of 1046 reviews
Rating 2 - Terrible. 29 out of 1046 reviews

9.8/10

Cleanliness

9.4/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Lindsay

Liked: Cleanliness, amenities, property conditions & facilities
Food amazing specially the breakfast!
Stayed 1 night in Feb 2026

10/10 Excellent

Moises

Liked: Cleanliness, amenities, property conditions & facilities
Absolutely outstanding place. Loved it
Stayed 1 night in Feb 2026

10/10 Excellent

Gladys

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love this place!
Stayed 1 night in Nov 2025

10/10 Excellent

Patricia

Stayed 1 night in Nov 2025

10/10 Excellent

Leland

Stayed 1 night in Nov 2025

10/10 Excellent

John

Liked: Cleanliness, amenities, property conditions & facilities
Room was spotless, staff was awesome. Great venue. This hotel never disappoints!!
Stayed 2 nights in Nov 2025

10/10 Excellent

TULA, COLUMBUS

Liked: Cleanliness, amenities, property conditions & facilities
The place. Hotel environment it’s nice. However, rooms needs an improvement.
Stayed 1 night in Nov 2025

10/10 Excellent

Juan Miguel

Stayed 1 night in Nov 2025

6/10 Okay

Sonia M

Traveled with partner
Liked: Amenities
The room was assigned to us has a strong humidity odor. Once we opened the windows it felt less.
Stayed 3 nights in Nov 2025

10/10 Excellent

clara

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
clean, inviting, calming, service exceptional , simply amazing
Stayed 1 night in Nov 2025

6/10 Okay

kent, Frederick

Business traveler
Liked: Cleanliness
Disliked: Amenities
I thought checking in there was a VIP welcome or something like tht with the room. I saw others receive it. Instead, I checked in with a colleague and learned they had breakfast included and I did not. I was paying a higher "VIP" rate. So not welcome drink. And no breakfast. Whatever. Its a nice facility. Unfortunately the glass museum is closed and the pharmacy museum was closed. So there was jsut the colonial art and silver. Hoepfully it will improve.
Stayed 1 night in Oct 2025

8/10 Good

Loretta

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful place to stay and tour. The old monastery is centrally located, historic, and well run hotel. Enjoyed!
Stayed 2 nights in Nov 2025

10/10 Excellent

Daniel

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
This place is absolutely amazing, from the staff, room, food, everything was unbelievable
Stayed 2 nights in Nov 2025

10/10 Excellent

Stephanie

Liked: Cleanliness, amenities
One of the best hotels i stayed at! Amazingly beautiful, enormous quiet rooms, great restaurant and spa facilities, lots of ruins and museums
Stayed 1 night in Nov 2025

10/10 Excellent

Daniel

Liked: Cleanliness, amenities, property conditions & facilities
The room, service, property all fantastic
Stayed 1 night in Nov 2025

10/10 Excellent

Erika

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Casa Santo Domingo was honestly a 10/10. It was amazing super clean, beautiful and so peaceful. Definitely worth the stay!
Stayed 3 nights in Nov 2025

10/10 Excellent

Carmen

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
There was not hot tub
Stayed 1 night in Nov 2025

10/10 Excellent

Michelle, Guatemala

Clean room, staff is helpfull, friendly. Rooms are comfortable. The property is amazingly well kept. You can walk everywhere.
Stayed 2 nights in Nov 2025

10/10 Excellent

Melissa

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Divina propiedad y todo lo que ofrece.
Stayed 3 nights in Nov 2025

10/10 Excellent

Jose, Norwood

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great overall stay
Stayed 1 night in Oct 2025

10/10 Excellent

Banelly

Traveled with group, Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
This is probably the best hotel in Antigua. They think about everything! It was built in what used to be a monastery, beautiful art and historic pieces in every corner. The hotel plays classical music everywhere, the halls smells like a peaceful haven, every corner is magical. The restaurant has a varied menu with delicious options, the staff are respectful and kind. I would come back 100 times if possible! Thank you for making my birthday an unforgettable experience.
Stayed 3 nights in Nov 2025

10/10 Excellent

Alice

Stayed 1 night in Oct 2025

10/10 Excellent

Ronaldo

Stayed 1 night in Oct 2025

8/10 Good

Estuardo Omar, Los Angeles

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
The staff is the strength of this hotel. Particularly speaking of the room attendants, waiters and porters.
Stayed 3 nights in Oct 2025

10/10 Excellent

Dawn

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Beautiful prooerty . Breathtaking ruins and museums ( free entry with hotel stay :)) and an incredible spa … in a private secluded area that is divine . Plus with Expedia an extra 20% off . Win win win . I love this place . Will be coming back and bringing other family members ! …
Stayed 2 nights in Nov 2025