Explore top 2026 4 Star Hotels in Colon
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Top Colon 4 Star hotels
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $197 total per night from Jul 17 to Jul 18
$197 total
Jul 17 - Jul 18
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...
9.2/10 Wonderful! (1,000 reviews)
"I really enjoyed my stay at Casco Viejo. I recommend purchasing the breakfast plan. The food was great. I enjoyed the area for walking. Not too far from Panama City."
Reviewed on Jul 13, 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
$128 nightly
The price is $141 total per night from Jul 26 to Jul 27
$141 total
Jul 26 - Jul 27
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.4/10 Very Good! (1,598 reviews)
"Rooms were immaculate, breakfast was great every morning. Cleaning was strange. I place my bag in the closet and the maid cleaned that out. I put in the closet to be safe, it WAS NOT."
Reviewed on Jul 14, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Jul 25 to Jul 26
$121 total
Jul 25 - Jul 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$140 nightly
The price is $154 total per night from Aug 7 to Aug 8
$154 total
Aug 7 - Aug 8
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
9/10 Wonderful! (1,064 reviews)
"Clean room"
Reviewed on Jul 14, 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $188 total per night from Jul 22 to Jul 23
$188 total
Jul 22 - Jul 23
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
8.6/10 Excellent! (1,004 reviews)
"Very nice stay, walking distance to Multi Plaza mall"
Reviewed on Jul 14, 2026
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Jul 23 to Jul 24
$105 total
Jul 23 - Jul 24
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Relax with a drink at the bar/lounge and enjoy free ...
9/10 Wonderful! (1,009 reviews)
"Great experience!!! Would definitely stay again."
Reviewed on Jul 14, 2026
Studio Coliving
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
7.8/10 Good! (590 reviews)
"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"
Reviewed on Mar 26, 2026
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
$88 nightly
The price is $97 total per night from Jul 21 to Jul 22
$97 total
Jul 21 - Jul 22
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.6/10 Excellent! (1,705 reviews)
"Nice location"
Reviewed on Jul 13, 2026
Radisson Hotel Panama Canal
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
$86 nightly
The price is $94 total per night from Jul 29 to Jul 30
$94 total
Jul 29 - Jul 30
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind ...
8.6/10 Excellent! (1,010 reviews)
"It wasn't a horrible stay but I wouldn't stay there again. I'll start with the negatives and finish with the positives. -s The hotel is very dated and looks like it. The sink in my room drained very slowly and the faucet in the tu dropped continuosly. Many of the outlets didn't work. But in all fairness ..."
Reviewed on Jul 11, 2026
Hotel Dann Carlton Panamá
C. Aquilino de la Guardia Panama City Panamá Province
$113 nightly
The price is $124 total per night from Jul 28 to Jul 29
$124 total
Jul 28 - Jul 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (423 reviews)
"Comfortable bed, very soft 💕. Breakfast is good . Clean rooms. Great lobby with a bar, newly renovated. The minuses: there is no microwave to warm up food. Also no common área with hotwater if one wants to make Coffee or tea. This would be a great plus. Great location. Walkable, lots of eats."
Reviewed on Jul 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Colon
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Colon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Colon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Colon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Colon hotel reviews by fellow wanderers
Principe Hotel and Suites
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"just a great place !!!!"
A verified traveler stayed at Principe Hotel and Suites
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