Explore top 2026 4 Star Hotels in Colon

Name: Decapolis Hotel Panama City
Price range: $111 total
Rating: 8.6

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Top Colon 4 Star hotels

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama

Fully refundableReserve now, pay when you stay

$183 nightly

$202 total

Sep 29 - Sep 30

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...

9/10 Wonderful! (1,009 reviews)

"This was the most unpleasant check-in experience I’ve ever had. I arrived at 8:30 a.m. and understood that rooms might not be ready, but I was told I’d have to pay over $200 for early check-in. I decided to wait instead. When I finally checked in, I mentioned a message I had received from the hotel, ..."

Reviewed on Aug 29, 2026

Waymore Hotel Spa & Casino

Calle Augusto Samuel Boyd y Calle Eusebi Panama City

Fully refundableReserve now, pay when you stay

$99 nightly

$110 total

Sep 11 - Sep 12

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Relax with a drink at the bar/lounge and enjoy free ...

9/10 Wonderful! (1,101 reviews)

"Place is a bit run down, but the location is pretty convenient and the rooms are decent."

Reviewed on Aug 30, 2026

Megapolis Hotel Panamá

Avenida Balboa Panama City

Fully refundableReserve now, pay when you stay

$163 nightly

$179 total

Sep 3 - Sep 4

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...

8.4/10 Very Good! (1,687 reviews)

"Good"

Reviewed on Aug 29, 2026

Courtyard by Marriott Panama Metromall

Avenida Domingo Diaz via Tocumen San Miguelito Panama

Fully refundableReserve now, pay when you stay

$101 nightly

$111 total

Sep 5 - Sep 6

Total with taxes and fees

This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

9/10 Wonderful! (1,009 reviews)

"The Courtyard Marriott at the Metromall was just perfect for my layover in Panama. After a long flight, to be welcomed by friendly staff and a clean and soft bed was all I needed."

Reviewed on Aug 29, 2026

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

Fully refundableReserve now, pay when you stay

$272 nightly

$272 total

Aug 31 - Sep 1

Total with taxes and fees

This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas ...

7.8/10 Good! (1,067 reviews)

"Staff was very"

Reviewed on Aug 29, 2026

Courtyard by Marriott Panama Multiplaza Mall

Via Israel Multiplaza Pacific Mall Panama City Panama

Fully refundableReserve now, pay when you stay

$118 nightly

$130 total

Sep 27 - Sep 28

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

Fully refundableReserve now, pay when you stay

$100 nightly

$110 total

Sep 21 - Sep 22

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...

7.8/10 Good! (1,004 reviews)

"We were on holiday and We did not want a housekeeper coming in to clean everyday. When we wanted towels or amenities, we asked the housekeeper who was in the flor at the time. We had a few challenges in the beginning with our bathroom and the drainage but that was rectified. The staff was very accomodating ..."

Reviewed on Aug 29, 2026

Radisson Hotel Panama Canal

Amador Avenue & Van Hook Street Panama City Panama

Fully refundable

$103 nightly

$113 total

Sep 5 - Sep 6

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind ...

Studio Coliving

Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

7.8/10 Good! (590 reviews)

"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"

Reviewed on Mar 26, 2026

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Decapolis Hotel Panama City

Avenida Balboa Con Multicentro Panama City Panama

Fully refundableReserve now, pay when you stay

$101 nightly

$111 total

Sep 27 - Sep 28

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...

8.6/10 Excellent! (1,723 reviews)

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Reviewed on Aug 29, 2026

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4 Star Hotels Colon

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Colon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Colon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Colon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.