$172 Cheap flights from McGhee Tyson to Des Moines Intl. (TYS to DSM)

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Find The Best Dates To Fly from McGhee Tyson to Des Moines Intl.

Compare Flight Prices from Knoxville to Des Moines

Affordable Airfare Tickets from TYS to DSM Airport

The cheapest flights to Des Moines Intl. found within the past 7 days were $249 round trip and $172 one way. Prices and availability subject to change. Additional terms may apply.

Tue, Oct 7 - Tue, Oct 14
TYS
Knoxville
DSM
Des Moines
$249 Roundtrip, found 20 hours ago
$249
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Oct 7 from Knoxville to Des Moines, returning Tue, Oct 14, priced at $249 found 20 hours ago
Sun, Jul 13 - Tue, Jul 22
TYS
Knoxville
DSM
Des Moines
$249 Roundtrip, found 5 days ago
$249
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Jul 13 from Knoxville to Des Moines, returning Tue, Jul 22, priced at $249 found 5 days ago
Thu, Oct 9 - Wed, Oct 15
TYS
Knoxville
DSM
Des Moines
$261 Roundtrip, found 20 hours ago
$261
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Thu, Oct 9 from Knoxville to Des Moines, returning Wed, Oct 15, priced at $261 found 20 hours ago
Mon, Jul 28 - Sat, Aug 2
TYS
Knoxville
DSM
Des Moines
$270 Roundtrip, found 1 day ago
$270
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Jul 28 from Knoxville to Des Moines, returning Sat, Aug 2, priced at $270 found 1 day ago
Thu, Jul 31 - Tue, Aug 5
TYS
Knoxville
DSM
Des Moines
$274 Roundtrip, found 1 day ago
$274
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Jul 31 from Knoxville to Des Moines, returning Tue, Aug 5, priced at $274 found 1 day ago
Sun, Jul 27 - Tue, Aug 5
TYS
Knoxville
DSM
Des Moines
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Jul 27 from Knoxville to Des Moines, returning Tue, Aug 5, priced at $284 found 1 day ago
Tue, May 13 - Tue, May 20
TYS
Knoxville
DSM
Des Moines
$287 Roundtrip, found 17 hours ago
$287
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, May 13 from Knoxville to Des Moines, returning Tue, May 20, priced at $287 found 17 hours ago
Sun, Oct 5 - Wed, Oct 15
TYS
Knoxville
DSM
Des Moines
$291 Roundtrip, found 20 hours ago
$291
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Sun, Oct 5 from Knoxville to Des Moines, returning Wed, Oct 15, priced at $291 found 20 hours ago
Sat, Jul 12 - Thu, Jul 17
TYS
Knoxville
DSM
Des Moines
$294 Roundtrip, found 5 days ago
$294
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Jul 12 from Knoxville to Des Moines, returning Thu, Jul 17, priced at $294 found 5 days ago
Tue, Jul 29 - Sat, Aug 2
TYS
Knoxville
DSM
Des Moines
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 29 from Knoxville to Des Moines, returning Sat, Aug 2, priced at $296 found 1 day ago

Frequently asked questions

Can I catch a flight from TYS to Des Moines Intl. Airport (DSM) right now?
Be sure to check out the Covid-19 Travel Advisor to discover if there are any current quarantine requirements and travel advice reports in effect in DSM when jet-setting from TYS.
Are there direct flights from TYS to Des Moines Intl. Airport?
There are no direct flights from McGhee Tyson Airport (TYS) to DSM. But we can direct you to airlines advertising flights with just one stopover. Try American Airlines, United Airlines and Delta.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Des Moines Intl. Airport (DSM), please visit our Customer Service Portal.
How long is the flight from McGhee Tyson Airport (TYS) to Des Moines Intl. Airport (DSM)?
Begin your travels feeling rested and relaxed by having a nap and some refreshments during your flight to DSM. With an usual travel time of 4 hours and 22 minutes from McGhee Tyson Airport (TYS), you’ll have ample time to enjoy both.
What is the flight distance from Knoxville Airport to Des Moines Intl. Airport (DSM)?
Forget watching a movie. You’ll be lucky to even manage some TV episodes on the quick hop between TYS and DSM. You’ll only be traveling 650 mi.
What airlines fly from McGhee Tyson Airport (TYS) to DSM?
Unfortunately, you won’t find any airlines that fly direct from TYS to DSM. But don’t let that come between you and a great vacation. Use any layover as an opportunity to have a shop, check out the local fare and potentially discover a new city you want to get to know better.
What airlines have practices regarding COVID-19 in place and use social distancing?
From the moment you enter the departure terminal to when you leave the arrivals terminal, if you’re flying with American Airlines, United Airlines or Delta you can be sure that COVID-19 measures and social distancing rules have been adhered to. Many airlines have introduced capped capacity flights and keeping the middle seat empty.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Flight information from Knoxville to Des Moines

 

Traveling From
McGhee Tyson
Traveling To
Des Moines Intl.
Shortest Flight Time
 hours mins
Earliest Departure Time
Latest Departure Time
Lowest Flight Price
$249

Route Info

Flight path for flights from McGhee Tyson Airport to Des Moines International Airport.


Origin:
TYS - McGhee Tyson Airport
Destination:
DSM - Des Moines International Airport
Distance:
898.00 miles


Discover our best flights from Knoxville TYS to Des Moines DSM. 

With 20 airlines to choose from on Travelocity, you can easily find the best option for you. Use our filters to sort by price, compare airlines, and find the most convenient flight times. 

 

Find our best return flights from Knoxville TYS to Des Moines DSM at the right price  

Airfares to Des Moines DSM from Knoxville TYS currently cost between $249 and $296. It’s usually cheaper to book a round trip than two separate one-way flights. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way flights from Knoxville TYS to Des Moines DSM 

If you want to be flexible about when you return, or keep your travel options open ended, a one-way flight could be just the ticket! You’ll find one-way airfares from Knoxville TYS to Des Moines DSM on Travelocity starting at $172. Prices and availability subject to change. Additional terms may apply. 

 

Get to Des Moines DSM from Knoxville TYS quicker with direct flights. 

Get to Des Moines faster, without the hassle of changing planes and moving baggage, by booking a direct flight. Expect your direct flight to DSM from TYS to take around hour(s) min(s).  

 

Find our cheapest airfares for flights from Knoxville TYS to Des Moines DSM

Find cheap flight deals by using our search filters to sort results starting with the lowest price airfares to DSM from TYS. Our Price Match Promise means if you find a lower rate on Travelocity.com or on another US-based website within 24 hours of booking, we’ll credit or refund the difference.  

 

Get our best airfare deals for your flight from Knoxville TYS to Des Moines DSM today 

If you’re flexible about when you travel, October is usually the cheapest month to fly from Knoxville TYS to Des Moines DSM. If you need to be more specific, search by date and arrival and departure times.Then, compare prices across different airlines, and sort results by lowest price first. 

 

Book flexible airline tickets for flights to Des Moines DSM from Knoxville TYS 

Some airlines let you change your travel dates without charging a fee. Use our ‘no change fee’ filter to see which flights to DSM from TYS have this option.  

 

Travel with confidence when you book flights to Des Moines DSM from Knoxville TYS with Travelocity 

We’ve secured fantastic deals with all the main airline carriers and it’s easy to compare, choose, and book with Travelocity. With 24/7 customer service and our free 'App', we’ll always keep you moving. 

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.