
$226 Cheap American Airlines flights from Panama City to Charleston (PTY to CHS)
Find The Best Day To Fly from Panama City to Charleston
Amazing American Airlines PTY to CHS Flight Deals
The cheapest flights to Charleston Intl. found within the past 7 days were $382 round trip and $226 one way. Prices and availability subject to change. Additional terms may apply.
Discover our best American Airlines flight from Panama City PTY to Charleston CHS
To find the best deals on flights to Panama City from Charleston with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Panama City PTY to Charleston CHS with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $382 to $412, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Panama City PTY to Charleston CHS
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Panama City to Charleston costs from $226. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Charleston CHS from Panama City PTY with American Airlines
To find a cheap American Airlines flight from Panama City PTY to Charleston CHS, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Panama City PTY to Charleston CHS
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as April, or if you book a flight with a stopover.
Find nonstop flights from Panama City PTY to Charleston CHS with American Airlines
If you’re keen to be on Charleston soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Panama City PTY to Charleston CHS
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Charleston CHS from Panama City PTY with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Reviewed on Jul 11, 2025

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Popular American Airlines Flight Routes from PTY
Top American Airlines Flight Routes from CHS
Top Flights for American Airlines originating from PTY
Domestic
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Chicago to Orlando (ORD - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to San Juan (LGA - SJU)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Dallas to Las Vegas (DFW - LAS)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Philadelphia to Orlando (PHL - MCO)
International
- Orlando to San Juan (MCO - SJU)
- New York to Santiago (JFK - STI)
- Chicago to San Juan (ORD - SJU)
- Philadelphia to Orlando (PHL - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- New York to Montego Bay (JFK - MBJ)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Los Angeles to San Salvador (LAX - SAL)
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