
$294 Cheap American Airlines flights from Jacksonville to Medellín (JAX to MDE)
Find The Best Day To Fly from Jacksonville to Medellín
Amazing American Airlines JAX to MDE Flight Deals
The cheapest flights to José María Córdova Intl. found within the past 7 days were $576 round trip and $294 one way. Prices and availability subject to change. Additional terms may apply.
MDE From JAX Economy Coach Packages on Similar Airlines



Discover our best American Airlines flight from Jacksonville JAX to Medellín MDE
To find the best deals on flights to Jacksonville from Medellín with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Jacksonville JAX to Medellín MDE with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $576 to $692, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Jacksonville JAX to Medellín MDE
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Jacksonville to Medellín costs from $294. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Medellín MDE from Jacksonville JAX with American Airlines
To find a cheap American Airlines flight from Jacksonville JAX to Medellín MDE, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Jacksonville JAX to Medellín MDE
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as January, or if you book a flight with a stopover.
Find nonstop flights from Jacksonville JAX to Medellín MDE with American Airlines
If you’re keen to be on Medellín soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Jacksonville JAX to Medellín MDE
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Medellín MDE from Jacksonville JAX with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| DFW | USA | Dallas-Fort Worth Intl. | 599 |
| CLT | USA | Charlotte-Douglas Intl. | 536 |
| ORD | USA | O'Hare Intl. | 317 |
| PHL | USA | Philadelphia Intl. | 247 |
| MIA | USA | Miami Intl. | 193 |
| DCA | USA | Ronald Reagan Washington National | 152 |
| PHX | USA | Sky Harbor Intl. | 141 |
| LAX | USA | Los Angeles Intl. | 81 |
| LGA | USA | LaGuardia | 72 |
| BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Medellín

Movich Hotel Las Lomas
The whole staff at the Movich Hotel Las Lomas was cordial and eager to help. The peacocks in the back of the garden add such character to the the hotel. Overall cleanliness was welcoming along their Holiday decorations.
Reviewed on Dec 10, 2025

Novotel Medellín El Tesoro
Excellent
Reviewed on Dec 9, 2025

Calle Flora Hotel by Jalo
El hotel estaba genial. La mayoría del personal muy amable. Mi único problema fue con respecto a la póliza escrita en letras pequeñas en la cual se te cobra $75 por cada persona diferente que le das acceso a la habitación. El hecho de que se asuma que cada persona que entra a la habitación conmigo ...
Reviewed on Dec 9, 2025
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