
$227 Cheap American Airlines flights from Knoxville to Houston (TYS to IAH)
Find The Best Day To Fly from Knoxville to Houston
Amazing American Airlines TYS to IAH Flight Deals
The cheapest flights to George Bush Intercontinental found within the past 7 days were $229 round trip and $227 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Knoxville TYS to Houston IAH
To find the best deals on flights to Knoxville from Houston with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Knoxville TYS to Houston IAH with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $229 to $276, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Knoxville TYS to Houston IAH
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Knoxville to Houston costs from $227. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Houston IAH from Knoxville TYS with American Airlines
To find a cheap American Airlines flight from Knoxville TYS to Houston IAH, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Knoxville TYS to Houston IAH
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from Knoxville TYS to Houston IAH with American Airlines
If you’re keen to be on Houston soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Knoxville TYS to Houston IAH
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Houston IAH from Knoxville TYS with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Houston

Houston Airport Marriott at George Bush Intercontinental
Reviewed on Jul 21, 2025

La Quinta Inn & Suites by Wyndham Houston Bush IAH South
Reviewed on Jul 23, 2025

SpringHill Suites by Marriott Houston Intercontinental Arprt
Reviewed on Jul 22, 2025
Top American Airlines Flight Routes from IAH
Top Flights for American Airlines originating from TYS
Domestic
- New York to Santiago (JFK - STI)
- Philadelphia to San Juan (PHL - SJU)
- Los Angeles to San Salvador (LAX - SAL)
- New York to Orlando (JFK - MCO)
- Los Angeles to New York (LAX - JFK)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Boston to Orlando (BOS - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to Santo Domingo (JFK - SDQ)
International
- Philadelphia to San Juan (PHL - SJU)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Chicago to Las Vegas (ORD - LAS)
- New York to Santiago (JFK - STI)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Ontario to San Salvador (ONT - SAL)
- New York to San Juan (JFK - SJU)
- Chicago to San Juan (ORD - SJU)
- Los Angeles to San Salvador (LAX - SAL)
Most Popular
- Boston to Dallas (BOS - DFW)
- Dallas to Phoenix (DFW - PHX)
- American Airlines Dallas (DFW) to Las Vegas (LAS) flights
- Los Angeles to Nashville (LAX - BNA)
- Nashville to New York (BNA - JFK)
- JetBlue Airways Boston (BOS) to Nashville (BNA) flights
- Dallas to New Orleans (DFW - MSY)
- Dallas to San Francisco (DFW - SFO)
- Philadelphia to Nashville (PHL - BNA)
- Dallas to Boston (DFW - BOS)
- Dallas to Atlanta (DFW - ATL)
- Dallas to London (DFW - LHR)
- Dallas to Detroit (DFW - DTW)
- Dallas to Orlando (DFW - MCO)
- Dallas to Cancun (DFW - CUN)
- Phoenix to Dallas (PHX - DFW)
- Los Angeles to Dallas (LAX - DFW)
- Chicago to Dallas (ORD - DFW)
- Nashville to Orlando (BNA - MCO)
- Dallas to Denver (DFW - DEN)
- Orlando to Dallas (MCO - DFW)
- Dallas to Chicago (DFW - ORD)
- Detroit to Dallas (DTW - DFW)
- Denver to Dallas (DEN - DFW)
- Atlanta to Dallas (ATL - DFW)
- New York to Dallas (JFK - DFW)
- Dallas to Miami (DFW - MIA)
- Philadelphia to Dallas (PHL - DFW)
- Dallas to Seattle (DFW - SEA)
- Dallas to Los Angeles (DFW - LAX)