Book Hotels in Whetsell, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Whetsell hotels

Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $154 total per night from Jun 2 to Jun 3
$154 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"Great"
Reviewed on May 7, 2026

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $132 total per night from Jun 7 to Jun 8
$132 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business ...
"."
Reviewed on May 16, 2026

Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from May 27 to May 28
$118 total
May 27 - May 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"This property is convenient to I-95 and is clean with a welcoming staff, lots of amenities, and great breakfast. Will be back on my next travels."
Reviewed on May 18, 2026

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $131 total per night from May 25 to May 26
$131 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Perfect halfway"
Reviewed on May 19, 2026

Fairfield Inn by Marriott Orangeburg
663 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from May 21 to May 22
$122 total
May 21 - May 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Everything was fine. The room, the staff were very accommodating, as the internet was down and they had to escort each visitor to their room to let them in."
Reviewed on May 19, 2026

Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from May 21 to May 22
$83 total
May 21 - May 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Room was clean, breakfast was enough but the pool was filled in with cement and after a grueling drive I was looking forward to a cooling dip"
Reviewed on May 19, 2026

Comfort Inn & Suites Santee
221 Britain St Santee SC
Fully refundable
$114 nightly
The price is $126 total per night from May 26 to May 27
$126 total
May 26 - May 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"The staff was phenomenal! Theresa checked me in on Friday night and was a pleasure to talk to throughout my visit! Breakfast was great and server Chris was very helpful and kind. Room attendants were all pleasant and accommodating! I will definitely make this hotel my first choice when I visit ..."
Reviewed on May 18, 2026

Peach Tree Inn
111 Conners Dr St. George SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $69 total per night from May 21 to May 22
$69 total
May 21 - May 22
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. If you want to take your pet along, this ...
"Clean room"
Reviewed on May 17, 2026

Quality Inn & Suites Santee I-95
8929 Old Number Six Highway Santee SC
Fully refundable
$59 nightly
The price is $66 total per night from Jun 9 to Jun 10
$66 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features 7 restaurants and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at ...
"Poorly ran hotel. Toilet would not flush and bath tub would not drain. Not happy. I have seen better places than this. No ice machine. Fire extinguisher missing from hall way. I would recommend tearing down and starting over. Will not stay there again."
Reviewed on May 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Whetsell hotel reviews by fellow wanderers

Baymont by Wyndham Santee
5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Room was clean, breakfast was enough but the pool was filled in with cement and after a grueling drive I was looking forward to a cooling dip"
A verified traveler stayed at Baymont by Wyndham Santee






