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Top Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $127 total per night from Mar 8 to Mar 9
$127 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Clean room. Lots of pot smell even though they said you would be charged 250 if you smoked or vaped in your room. Im curious how many people got charged🤔very nice staff. Quiet on the 7th floor. Perfect location. Great breakfast. Bartenders didnt know how to make a chocolate martini. First one was ...
Reviewed on Feb 22, 2026

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Mar 1 to Mar 2
$122 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Room was completely clean and organized. The staff was very friendly and helpful! No disturbances throughout the night!
Reviewed on Feb 21, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $119 total per night from Mar 13 to Mar 14
$119 total
Mar 13 - Mar 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Was a great stay thanks
Reviewed on Feb 19, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Mar 1 to Mar 2
$106 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Guest services, it was quiet and the food was great.
Reviewed on Feb 15, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Mar 8 to Mar 9
$122 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
All was very good. Very clean. One of the best beds I’ve slept in a hotel. It was my first time in a comfort inn. I will be choosing them again on my travels!!
Reviewed on Feb 22, 2026

Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd Granite City IL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Feb 24 to Feb 25
$70 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Staff was very friendly..room was very clean and spacious (bathroom small) breakfast was nice..was impressed with the large refrigerator in room and microwave provided without the extra charge...great stay for the value!
Reviewed on Feb 22, 2026

Quality Inn O'Fallon IL - St. Louis
1409 W US 50 O'Fallon IL
Fully refundableReserve now, pay when you stay
$45 nightly
The price is $51 total per night from Mar 1 to Mar 2
$51 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Best stuff
Reviewed on Feb 22, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $56 total per night from Mar 1 to Mar 2
$56 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
They're lying people has roaches no one really speaks or understand english facility is dirty dog crap everywhere outside
Reviewed on Feb 22, 2026

Americas Best Value Inn Collinsville St. Louis
552 Ramada Blvd Collinsville IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $74 total per night from Feb 24 to Feb 25
$74 total
Feb 24 - Feb 25
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Multilingual staff ...
Not in good condition old amenities.
Reviewed on Dec 21, 2025
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$63 nightly
The price is $71 total per night from Feb 24 to Feb 25
$71 total
Feb 24 - Feb 25
Total with taxes and fees
6.4/10 (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Quality Inn O'Fallon IL - St. Louis
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Staff was really helpful and caring about my situation. The room was clean and quiet. I felt safe during my stay. "
A verified traveler stayed at Quality Inn O'Fallon IL - St. Louis
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