Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 23 to Nov 24
$106 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice place…
Reviewed on Nov 10, 2025
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Nov 23 to Nov 24
$118 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Spacious and clean
Reviewed on Nov 7, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 20 to Nov 21
$106 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Room was clean. Staff was great
Reviewed on Nov 9, 2025
Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Nov 16 to Nov 17
$123 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Excellent
Reviewed on Nov 9, 2025
Best Western Plus Pontoon Beach
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Nov 19 to Nov 20
$95 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The room was great, the staff was so polite and helpful. We were pleased with breakfast. My children loved the machine they could get hot chocolate from.
Reviewed on Nov 8, 2025
DoubleTree by Hilton Mt. Vernon
222 Potomac Blvd, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $133 total per night from Nov 21 to Nov 22
$133 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Nice room and very pleasant staff
Reviewed on Nov 6, 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Nov 23 to Nov 24
$76 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Staff very cordial. We were satisfied with our stay. Location is near food and commerce options. LOTS of handicap parking = the WHOLE front row near the building. Trim strip missing in bathroom made it appear less than clean. HARD TO GET IN & OUT OF TUB FOR BATH as only one puny grab bar = likely ...
Reviewed on Nov 4, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $54 total per night from Nov 20 to Nov 21
$54 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room was very comfortable with a good layout. The mattress was comfortable. The climate control was easy to operate and efficient. Every staff member we met was friendly.
Reviewed on Nov 9, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Nov 30 to Dec 1
$92 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I was clean
Reviewed on Oct 29, 2025
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr, Caseyville, IL
$62 nightly
The price is $70 total per night from Nov 15 to Nov 16
$70 total
Nov 15 - Nov 16
Total with taxes and fees
6.2/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Plaza Hotel Mt. Vernon
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Nice place…"
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
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