Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Enjoy the indoor pool at this St. Louis hotel
Choose dates to view prices
Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG





Reviews
9.6 out of 10
Exceptional
Popular amenities
Explore the area

4250 Midamerica Lane, St. Louis, MO, 63129
- Place, Busch Stadium16 min drive
- Place, Gateway Arch17 min drive
- Place, St. Louis Union Station18 min drive
- Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)29 min drive
Room options
View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)
9.4 out of 10
Exceptional
(13 reviews)
View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)
9.6 out of 10
Exceptional
(4 reviews)
View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Suite, 1 Bedroom (2 Queen, Extra Living Area)
9.6 out of 10
Exceptional
(31 reviews)
View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)
9.0 out of 10
Wonderful
(7 reviews)
View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)
10.0 out of 10
Exceptional
(2 reviews)
View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr)
9.2 out of 10
Wonderful
(5 reviews)
View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Standard Room, 1 King Bed (Bath Shwr Combo)
9.6 out of 10
Exceptional
(17 reviews)
View all photos for Standard Room

Standard Room
View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)
View all photos for Standard Room, 2 Queen Beds

Standard Room, 2 Queen Beds
9.4 out of 10
Exceptional
(75 reviews)
You may also like
Ad

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Fenton
- Pool
- Hot tub
- Breakfast included
- Pet friendly
4.0 out of 5, Very Good, 1,256 reviews
$89 nightly
The price is $103
May 17 - May 18
Total with taxes and fees
About the neighborhood
About this property
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Similar properties

Hampton Inn & Suites St. Louis/South I-55
St. Louis
Hampton Inn & Suites St. Louis/South I-55
- Pool
- Breakfast included
- Pet friendly
- Parking included
4.8 out of 5, Exceptional, 1,002 reviews
$127 nightly
The price is $146
May 10 - May 11
Total with taxes and fees
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews
Reviews
9.6
Exceptional
9.6/10
Cleanliness
9.6/10
Staff & service
9.6/10
Amenities
9.6/10
Property conditions & facilities
Reviews
Feb 3, 2026
Liked: Cleanliness, staff & service, amenities
Stayed 1 night in Feb 2026
10/10 Excellent
jonathan
Feb 2, 2026
jonathan
Stayed 1 night in Jan 2026
2/10 Terrible
Christine
Jan 31, 2026
Christine
Stayed 1 night in Jan 2026
10/10 Excellent
George
Business traveler
Jan 31, 2026
Liked: Cleanliness, staff & service, amenities
George
Stayed 1 night in Jan 2026
10/10 Excellent
Ashley, Bloomfield
Jan 26, 2026
Ashley
Stayed 1 night in Jan 2026
10/10 Excellent
Tonya
Business traveler
Jan 25, 2026
Liked: Cleanliness, staff & service, amenities
Tonya
Stayed 1 night in Jan 2026
8/10 Good
Alyssa
Jan 19, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Alyssa
Stayed 1 night in Jan 2026
8/10 Good
Eleanor
Traveled with family
Jan 18, 2026
Liked: Cleanliness, staff & service, amenities
Eleanor
Stayed 2 nights in Jan 2026
10/10 Excellent
Aneta
Jan 15, 2026
Liked: Cleanliness, staff & service, amenities
Aneta
Stayed 1 night in Jan 2026
10/10 Excellent
Jennifer
Traveled with partner
Jan 12, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Jennifer
Stayed 1 night in Jan 2026
10/10 Excellent
Arielle
Jan 10, 2026
Arielle
Stayed 1 night in Jan 2026
10/10 Excellent
Pamela
Jan 10, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Pamela
Stayed 1 night in Jan 2026
8/10 Good
Tracy
Jan 9, 2026
Tracy
Stayed 1 night in Jan 2026
8/10 Good
Shilouh, Chester
Jan 7, 2026
Shilouh
Stayed 2 nights in Oct 2025
10/10 Excellent
Brandy
Jan 4, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brandy
Stayed 1 night in Jan 2026
10/10 Excellent
Kevin
Jan 4, 2026
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Kevin
Stayed 2 nights in Jan 2026
10/10 Excellent
Christopher
Jan 4, 2026
Christopher
Stayed 1 night in Jan 2026
10/10 Excellent
Mary
Jan 3, 2026
Mary
Stayed 5 nights in Dec 2025
10/10 Excellent
Anita
Traveled with family
Jan 2, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Anita
Stayed 2 nights in Nov 2025
10/10 Excellent
James
Traveled with family
Dec 31, 2025
James
Stayed 4 nights in Dec 2025
10/10 Excellent
Zackariah
Traveled with family and small children
Dec 30, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Zackariah
Stayed 1 night in Dec 2025
10/10 Excellent
Arielle
Business traveler, Traveled with partner
Dec 29, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Arielle
Stayed 1 night in Dec 2025
10/10 Excellent
Edwin
Dec 28, 2025
Edwin
Stayed 1 night in Dec 2025
8/10 Good
Therese
Dec 27, 2025
Liked: Cleanliness, staff & service, amenities
Therese
Stayed 4 nights in Dec 2025
10/10 Excellent
Walt
Traveled with family
Dec 26, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Walt
Stayed 1 night in Dec 2025
Travelocity's Latest Trends
Hotels
- Cheap Hotels in Yadkinville
- The Rockaway Hotel
- Chateau On The Lake Resort Spa and Convention Center
- River City Casino & Hotel
- Condos Daytona Beach
- Vacation Homes Truckee
- Club Wyndham Mountain Vista
- Branson Hillside Hotel
- Lodge Of Four Seasons Golf Resort, Marina & Spa
- Drury Inn & Suites Sikeston, MO
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- DoubleTree by Hilton Napa Valley - American Canyon
- Cheap Hotels in Berne
- Still Waters Resort
- B&B Vicksburg
- Hyatt Vacation Club at The Lodges at Timber Ridge, Branson
Flights
- British Airways Nairobi (NBO) to Toronto (YYZ) flights
- JetBlue Airways North Syracuse (SYR) to Fort Lauderdale (FLL) flights
- Flights from Greater Fredericton Intl.
- Delta Los Angeles (LAX) to Charlotte (CLT) flights
- Flights to Norfolk
- Atlanta to Cincinnati (ATL - CVG)
- Flights to Orlando
- Providence to Washington (PVD - IAD)
- JetBlue Airways Washington (DCA) to Campinas (VCP) flights
- Flights from Thunder Bay Intl.
- Lufthansa Chantilly (IAD) to Belgrade (BEG) flights

















