Book Hotels in South Salem, OH

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top South Salem hotels

Jungle House Luxury Stays - Downtown Chillicothe

Jungle House Luxury Stays - Downtown Chillicothe

5 out of 5
241 West Water Street Chillicothe OH
$124 nightly
The price is $142 total per night from Aug 23 to Aug 24
$142 total
Aug 23 - Aug 24
Total with taxes and fees
This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the 2 conference rooms, 24-hour ...
"Good value for cost."

Reviewed on Jul 14, 2026

Opens in a new windowJungle House Luxury Stays - Downtown Chillicothe
Christopher Inn and Suites

Christopher Inn and Suites

2.5 out of 5
30 North Plaza Boulevard Chillicothe OH
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $172 total per night from Aug 23 to Aug 24
$172 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the laundry ...
"The hotel is a bit dated, but clean. Beds were comfortable enough. I got up from bed 4 times through the night because AC would stop kicking on, and the room would warm up."

Reviewed on Aug 21, 2026

Opens in a new windowChristopher Inn and Suites
Holiday Inn Express Chillicothe East by IHG

Holiday Inn Express Chillicothe East by IHG

1003 E Main Street Chillicothe OH
Fully refundable
$114 nightly
The price is $131 total per night from Sep 10 to Sep 11
$131 total
Sep 10 - Sep 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"it was good, breakfast cinamon rolls were amazing"

Reviewed on Aug 18, 2026

Opens in a new windowHoliday Inn Express Chillicothe East by IHG
Quality Inn Chillicothe

Quality Inn Chillicothe

2.5 out of 5
20 N Plaza Blvd Chillicothe OH
Fully refundable
$108 nightly
The price is $123 total per night from Sep 20 to Sep 21
$123 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with ...
"The room was clean and recently appeared to be renovated but the bathroom door didn't fit the frame and the toilet paper holder was loose. One of the better breakfasts with pecan and walnuts for the oatmeal, potatoes, sausage, biscuits and gravy... Lots of choices."

Reviewed on Aug 21, 2026

Opens in a new windowQuality Inn Chillicothe
Days Inn by Wyndham Hillsboro

Days Inn by Wyndham Hillsboro

2.5 out of 5
103 Harry Sauner Rd Hillsboro OH
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Aug 24 to Aug 25
$117 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Weirdo’s smoking pot in the parking lot. Dogs in rooms barking. Heavy cigarette smoke smell throughout. Manager folding towels in lobby. Seems like a flop house for transient construction workers Reservations made on a Visa card. Manager says our card is a Master Card with other serial numbers We ..."

Reviewed on Aug 16, 2026

Opens in a new windowDays Inn by Wyndham Hillsboro
Executive Inn

Executive Inn

2.5 out of 5
24 North Bridge Street Chillicothe OH
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $74 total per night from Aug 23 to Aug 24
$74 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
Opens in a new windowExecutive Inn
Best Western Adena Inn

Best Western Adena Inn

2.5 out of 5
1250 N Bridge Street Chillicothe OH
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $122 total per night from Aug 31 to Sep 1
$122 total
Aug 31 - Sep 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
Opens in a new windowBest Western Adena Inn
Days Inn by Wyndham Washington Court House

Days Inn by Wyndham Washington Court House

2.5 out of 5
1810 Victoria Street Washington Court House OH
$97 nightly
The price is $110 total per night from Aug 28 to Aug 29
$110 total
Aug 28 - Aug 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. Staff at ...
Opens in a new windowDays Inn by Wyndham Washington Court House
Comfort Inn Piketon near Fairgrounds

Comfort Inn Piketon near Fairgrounds

2.5 out of 5
7525 US 23 Piketon OH
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Sep 21 to Sep 22
$107 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowComfort Inn Piketon near Fairgrounds
Don't see what you're looking for?
See all available properties in South Salem
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in South Salem?
Family trips are where treasured memories are made, but it's no secret that traveling with little ones can be challenging. These kid-friendly South Salem hotels come with perks that aim to keep young and old alike comfortable and happy: Unpack your bags at Experience the Unforgettable Paint Valley in SW Ohio! Unplug, Unwind, Refresh!. It comes with a playground, a travel crib and a flair for making families feel at home. Also consider staying at LAKE HOUSE ON ROCKY FORK!. It offers a king bed, a firepit and plenty of opportunities to hang out as a family.
Where can I find cheap hotels in South Salem?
At Travelocity you'll find really nice hotels in South Salem at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near South Salem rather than in South Salem. We may find you even better rates, too.
How do I find the best South Salem hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in South Salem then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in South Salem?
The cheapest hotel in South Salem is $74. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in South Salem?
There are 135 hotels in South Salem on Travelocity.
What are the best hotels in South Salem?
South Salem has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in South Salem for you!
When is the best time to visit South Salem?
If you want the joy of a fun-filled trip in peak season, visit South Salem during May, June and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in South Salem?
Based on historic data is usually the cheapest month to visit South Salem. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in South Salem?
There are multiple hotels in South Salem that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to South Salem. We have plenty of kid-friendly hotels in South Salem to choose from on Travelocity!
Why book a hotel in South Salem through Travelocity?
Because we have the top hotels in South Salem! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in South Salem on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent South Salem hotel reviews by fellow wanderers

Quality Inn Chillicothe

Quality Inn Chillicothe

4 out of 5
Posted 9 hours ago
Travelocity Verified Review
"The room was clean and recently appeared to be renovated but the bathroom door didn't fit the frame and the toilet paper holder was loose. One of the better breakfasts with pecan and walnuts for the oatmeal, potatoes, sausage, biscuits and gravy... Lots of choices."
A verified traveler stayed at Quality Inn Chillicothe
Quality Inn Chillicothe