South Central Houston Vacation Packages 2026 from $268

South Central Houston flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Golden Motel Near Houston Medical Center

Southeast Houston

Save 100% on your flight

$268

per person

Jun 12 - Jun 14

found 1 hour ago

Roundtrip flight included

Miami (MIA) to Houston (IAH)

Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. A fireplace in the lobby and a safe deposit box are also provided.

Holiday Inn Club Vacations Galveston Seaside Resort by IHG

West End

Save 100% on your flight

$516

per person

May 21 - May 24

found 1 hour ago

Roundtrip flight included

Dallas (DFW) to Houston (IAH)

2 outdoor tennis courts, an outdoor pool, and a gym are all featured at this smoke-free resort. There's fun for all ages with mini golf and a playground, and barbecue grills are available on site. Enjoy a meal from the restaurant and perks like free WiFi.

Hotel Granduca Houston

The Galleria

$814

per person

May 22 - May 25

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Houston (IAH)

This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Families will appreciate the arcade/game room and onsite laundry facilities. Enjoy the outdoor pool and perks like free WiFi and a free area shuttle.

Tx Home Group- Houston

Northside

$439

per person

Jul 9 - Jul 13

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Houston (IAH)

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace is also provided.

Top South Central Houston hotels deals

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Free Cancellation

Reserve now, pay when you stay

$237 nightly

$277 total

Apr 19 - Apr 20

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the outdoor pool and perks like a free area shuttle.

Pool

Pet friendly

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Free Cancellation

Reserve now, pay when you stay

$100 nightly

$117 total

Apr 26 - Apr 27

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. There's a poolside bar on site, and a 24-hour front desk and laundry facilities are also provided.

Pool

Free WiFi

The Westin Houston Medical Center/Museum District

1709 DRYDEN ROAD Houston TX

Free Cancellation

Reserve now, pay when you stay

$147 nightly

$170 total

Apr 19 - Apr 20

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. You'll appreciate the 24-hour gym, poolside bar, and laundry facilities.

Pool

Pet friendly

InterContinental Houston by IHG

6750 Main St Houston TX

Free Cancellation

$180 nightly

$211 total

May 17 - May 18

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and perks like a free area shuttle.

Pool

Pet friendly

DoubleTree by Hilton Houston Medical Center Hotel & Suites

6800 Main Street Houston TX

Free Cancellation

Reserve now, pay when you stay

$105 nightly

$123 total

Apr 25 - Apr 26

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Unwind with a drink at the bar/lounge and enjoy perks like a free area shuttle.

Pool

Pet friendly

Extended Stay America Suites Houston Med Ctr Braeswood Bl

1301 Braeswood Blvd Houston TX

Free Cancellation

Reserve now, pay when you stay

$73 nightly

$85 total

Apr 23 - Apr 24

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

MD Anderson Cancer Center

Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.

Rice University

Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed art scene and great live music.

Houston Zoo

Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.

Frequently asked questions

How much are vacation packages to South Central Houston?

Starting from as low as $268, hotel and flight packages are a fabulous way to stretch your vacation budget. South Central Houston, here you come!

Where can I get the best vacation package deals for South Central Houston?

With around 400 air carriers and 1,000,000 hotels across the world, it's hard to top Travelocity. Look through our extensive range and grab an affordable South Central Houston vacation package. Don't you just love it when planning a trip is that easy?

Why should I purchase my South Central Houston vacation package via Travelocity?

Because we believe in creating unforgettable travel experiences. From hotels and flights to car rentals and activities, our packages make it a breeze to save. Our customer support team is available 24/7 to ensure your needs are taken care of. We also offer a Price Match Guarantee, so you can secure your vacation knowing you've scored the best deal possible. How? If you find a lower price, we'll match it!

Can I save on my South Central Houston car rental if I book it with hotels and flights?

Certainly. And our South Central Houston vacation packages will help you do it. In only a few clicks you can save cash and time by booking everything in one place. Pick up the keys to your rental car and do your vacation your way. Looking for things to do? Add some tours or experiences to your package and make savings on those too.

Which airport is best for South Central Houston?

George Bush Intercontinental Airport (IAH) is where many people prefer to touch down. Depending on where you're going in South Central Houston, William P. Hobby Airport (HOU) and Ellington Field Airport (EFD) are other choices for you to look into.

What is there to do in South Central Houston?

South Central Houston boasts hidden surprises around every corner, however make sure you get to Houston Zoo and Houston Natural Science Museum during your stay. These two attractions can't be missed.