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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
3-star hotel near Mayo Clinic Florida

Choose dates to view prices

Photo gallery for Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Relax by the fire pit in our outdoor patio area, surrounded by comfortable seating and a modern backdrop.
Relax in our spacious lobby with a comfortable sofa and bar stools, surrounded by a modern kitchen area and large windows offering a view of lush greenery.
Stunning hotel with a central entrance and arched windows, set amidst a beautifully manicured lawn with palm trees.
Check-in and unwind in our reception area, featuring two desks with computer monitors and a view of lush greenery.
Relax in our inviting lobby, featuring a comfortable seating area, fireplace, and large flat-screen TV.

Popular amenities

  • Bar
  • Kitchen
  • Pet friendly
  • Housekeeping

Explore the area

Map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
  • Mayo Clinic Florida
    ‪17 min walk‬
  • University of North Florida
    ‪7 min drive‬
  • St. Johns Town Center
    ‪8 min drive‬
  • Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪37 min drive‬

Room options

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking, Corner

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 533 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 569.3 sq ft
  • Sleeps 5
  • 1 Double Bed

View all photos for Suite, 1 Bedroom, Non Smoking, Corner

Suite, 1 Bedroom, Non Smoking, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking, Corner

10.0 out of 10
Exceptional
(2 reviews)
  • 646 sq ft
  • Sleeps 5
  • 1 Double Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking

Fridge, microwave, stovetop, dishwasher

Studio Suite, 1 King Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(78 reviews)
  • 407 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking

Suite, 1 Bedroom, Non Smoking | Living room | 55-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom, Non Smoking

9.8 out of 10
Exceptional
(17 reviews)
  • 560 sq ft
  • Sleeps 5
  • 1 Double Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 409.0 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Roll-In Shower)

1 bedroom, in-room safe, desk, laptop workspace

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Roll-In Shower)

  • 409.0 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking, Corner (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking, Corner (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 533.7 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking, Corner (Mobility/Hearing Access, Roll-In Shwr)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 645.8 sq ft
  • Sleeps 5
  • 1 Double Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Tub)

8.0 out of 10
Very good
(4 reviews)
  • 409.0 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

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About the neighborhood

Jacksonville

Southside stay.Your stay at this Southside hotel places you within 2 miles (3 km) of Harbor City Municipal Golf Course and Mayo Clinic Florida. Windsor Commons Shopping Center and Windsor Parke Golf Club are also within 6 miles (10 km).

What's nearby

  • Mayo Clinic Florida - 17 min walk - 0.9 miles
  • University of North Florida - 7 min drive - 6.0 miles
  • St. Johns Town Center - 8 min drive - 7.2 miles
  • Jacksonville Beach Pier - 10 min drive - 5.9 miles
  • TPC Sawgrass - 14 min drive - 8.7 miles

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 13 min drive

Restaurants

  • ‪McDonald's - ‬5 min drive
  • ‪Starbucks - ‬4 min drive
  • ‪Bono's Pit Bar-B-Q - ‬4 min drive
  • ‪Orange Blossoms - ‬5 min drive
  • ‪Freddy's Frozen Custard & Steakburgers - ‬6 min drive

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3-star hotel near Mayo Clinic Florida
Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers its guests an outdoor pool and a 24-hour fitness center. You can enjoy a drink at one of the bars, which include a poolside bar and a bar/lounge. Free breakfast is served daily. A computer station is on site and WiFi is free in public spaces.

A 24-hour business center, 2 meeting rooms, and coworking spaces are available. Event space at this hotel measures 2678 square feet (249 square meters) and includes conference space. Barbecue grills, multilingual staff, and a garden are also featured at the business-friendly Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Self parking is free.

This 3-star Jacksonville hotel is smoke free.

  • 1 building
  • 155 guestrooms or units
  • 7 levels
  • 2678 sq ft of conference space
  • 249 sq m of conference space
  • Built in 2020
  • Buffet breakfast (free)
  • Poolside lounge chairs
  • Business center (24 hours)
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Staff is multilingual
  • Storage area for luggage
  • Front-desk safe
  • Concierge
  • Grocery service (free)
  • Wedding services available
  • Convenience store
  • Garden
  • BBQ grill(s)
  • Outdoor picnic space
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Elevator
  • No smoking on site
  • Water dispenser
  • Bar or lounge
  • Bar by the pool
Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers 155 air-conditioned accommodations with laptop-compatible safes and coffee/tea makers. Accommodations offer separate sitting areas. 55-inch Smart televisions come with premium cable channels and Netflix. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and separate dining areas. Bathrooms include bathtubs or showers, complimentary toiletries, and hair dryers.

This Jacksonville hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered daily and change of bedsheets can be requested. Housekeeping is provided on request.

Languages

English, Spanish

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Aug 3 - Aug 4
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Property amenities

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical outlets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

Room amenities

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Stovetop
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Energy-saving switches in guestrooms
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation

Access methods

Staffed front desk

Pets

  • Pets: USD 150.00 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 40 lbs per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Deposit: USD 125 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 150.00 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Union Pay. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards in each accommodation. Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

We should mention

  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Frequently asked questions

How close is Residence Inn By Marriott Jacksonville - Mayo Clinic Area to the airport?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area is 11.1 mi (13-min drive) away from the Jacksonville, FL (CRG-Jacksonville Executive at Craig) airport, the closest popular airport to the property.

How much does it cost to stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

As of Jul 24, 2025, prices found for a 1-night stay for 2 adults at Residence Inn By Marriott Jacksonville - Mayo Clinic Area on Aug 24, 2025 start from $162.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have an airport shuttle?

Airport shuttle services are not available at Residence Inn By Marriott Jacksonville - Mayo Clinic Area.

How close is Residence Inn By Marriott Jacksonville - Mayo Clinic Area to the beach?

This hotel is 4.5 mi (7-min drive) from Atlantic Beach and 5.5 mi (9-min drive) from Northeast Florida Beaches. Don't forget your sunscreen!

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area offer free breakfast?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers free buffet breakfast on weekdays between 6:30 AM and 9:00 AM and weekends between 7:00 AM and 9:30 AM.

Is there a casino at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

No, there is no casino at this hotel.

What time is check-in at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM.

Is there free parking at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

This hotel offers free self parking.

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a pool?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area features an outdoor pool.

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a spa?

There are no spa services available at this hotel.

How close is Residence Inn By Marriott Jacksonville - Mayo Clinic Area to downtown Jacksonville?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area is 14.1 mi away from Jacksonville.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 324 out of 409 reviews
Rating 8 - Good. 60 out of 409 reviews
Rating 6 - Okay. 10 out of 409 reviews
Rating 4 - Poor. 11 out of 409 reviews
Rating 2 - Terrible. 4 out of 409 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay!

This is a wonderful place to stay. It offers all of the services that you need. It is in a beautiful setting with great amenities.
Stayed 2 nights in Apr 2025

10/10 Excellent

Tina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice
Stayed 3 nights in Apr 2025

10/10 Excellent

Rina, Columbia

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Apr 2025

10/10 Excellent

Victor

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Apr 2025

10/10 Excellent

Margaret

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Feb 2025

8/10 Good

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Rhonda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

8/10 Good

Patrick

Liked: Cleanliness, staff & service, property conditions & facilities
Quiet and comfortable
Stayed 3 nights in Apr 2025

8/10 Good

Jonathan

Stayed 2 nights in Apr 2025

10/10 Excellent

Stephanie

Liked: Staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Andrea

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay

This hotel was better than expected. Studio suite had everything needed for an extended stay including a full size cridhe, dishwasher cookware, dishes.Room was clean and comfortable. Staff were friendly and complimentary breakfast was good with options.
Stayed 2 nights in Apr 2025

10/10 Excellent

Verified traveler

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Nice hotel

I had a terrible next-door neighbor family, whose kids were extremely loud obnoxious from 1030pm until 1:30 AM. Next morning, I requested a change of room and the staff, especially the front desk, guy named Michael. He was very accommodating and moved to another room. He also drives a shuttle from Hotel to Mayo Clinic, where I had to go for a couple of procedures. He is really an exceptional staff person. One thing I would recommend is one day people who are paying customers, and they have to move from one room to another not because they want to, but they have no choice. The staff from Hotel should be able to help move the staff. They have an offer that even though they were walking with me to move me from one room to another. I moved all my stuff by myself
Stayed 4 nights in Apr 2025

10/10 Excellent

Raul Alexander

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent
Stayed 1 night in Mar 2025

10/10 Excellent

Sara

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place highly recommend
Stayed 2 nights in Mar 2025

10/10 Excellent

John, Cape Coral

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Q at the front desk was the absolute best. She went out of her way everyday to help us.
Stayed 4 nights in Mar 2025

10/10 Excellent

Gregory

Stayed 1 night in Mar 2025

2/10 Terrible

David

Stayed 2 nights in Mar 2025

10/10 Excellent

Tara

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Mar 2025

10/10 Excellent

David

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property close to Mayo Clinic. I liked the kitchens if you need to stay long.
Stayed 1 night in Mar 2025

10/10 Excellent

Mario

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Only thing I would change is the bar and restaurant area. A bit awkward but understandable that most people just want to go to their room. We were there 2 solid weeks but could have used a beer after 12 hours days of scans and treatments but maybe that is just us. We only ate out once at Joes crab which cost over $100 with just one beer??? Better value at the hotel. Or uber eat.
Stayed 4 nights in Jan 2025

10/10 Excellent

Shayan

Stayed 3 nights in Mar 2025

10/10 Excellent

drGayle

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Feb 2025

10/10 Excellent

Eun Bee

Stayed 2 nights in Feb 2025

10/10 Excellent

Gerard

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel has many patients that go to Mayo Clinic stay. There is not adequate. Handicap parking. I stay there often and almost always need to park on the side of the building and walk. Also the room service is a nice addition. A suggestion would be to have a direct line to call the restaurant to place orders, currently you need to call the front desk.
Stayed 2 nights in Mar 2025

10/10 Excellent

Carolina, Coral Gables

Stayed 4 nights in Feb 2025