Book Hotels in Commerce, MO

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Top Commerce hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jun 3 to Jun 4
$102 total
Jun 3 - Jun 4
Total includes taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great Place
"Friendly staff clean rooms."

Reviewed on May 26, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
$99 nightly
The price is $112 total per night from Jun 8 to Jun 9
$112 total
Jun 8 - Jun 9
Total includes taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"I thought the property was very clean and appealing. Our check in clerk for our 1st night stay on May 22nd was very friendly, and helpful, however our 2nd stay on May 25th our clerk was unpleasant never said hello never smiled. She wasn't rude but she seemed very unfriendly and like she didn't want ..."

Reviewed on May 27, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $114 total per night from Jun 8 to Jun 9
$114 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"The bed was so comfortable. The front desk service was outstanding. I had my dog with me. Very accommodating."

Reviewed on May 29, 2025

Drury Inn & Suites Sikeston, MO
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $131 total per night from Jun 8 to Jun 9
$131 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Overall great stay!
"Overall we had a great stay here for just a night in town for a soccer tournament. I had filtered out hotels that had a pool and somehow this one slipped through but it does not have a pool. I also filtered by hotels that included free breakfast, this hotel has a restaurant but breakfast is not free. ..."

Reviewed on May 19, 2025

Courtyard by Marriott Cape Girardeau Downtown
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Jun 1 to Jun 2
$121 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel features a casino and 2 restaurants. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public ...
"Yes"

Reviewed on May 30, 2025

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jun 1 to Jun 2
$79 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Very clean and staff was friendly"

Reviewed on May 25, 2025

Pear Tree Inn Cape Girardeau West
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Jun 1 to Jun 2
$91 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The property was clean, conveniently located, and the staff was always friendly."

Reviewed on May 28, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Jun 3 to Jun 4
$66 total
Jun 3 - Jun 4
Total includes taxes and fees
A seasonal outdoor pool is featured at this hotel, along with free WiFi in public areas and express check-out. Staff at the 24-hour front desk can provide around-the-clock ...
"Clean and comfortable"

Reviewed on May 26, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
$78 nightly
The price is $94 total per night from Jun 15 to Jun 16
$94 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
"The gym conference room and games my basketball team enjoyed the stay service was excellent also"

Reviewed on May 26, 2025

Candlewood Suites Cape Girardeau by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Commerce?
Family vacations are where you make the best memories, but traveling with young ones can be stressful. These kid-friendly Commerce hotels offer perks that aim to keep visitors of all ages comfortable and happy: Your gang will enjoy staying at Serenity South – Gardens, River-Views, and Refreshing Space. A water park and animal viewing activities are among the things that help make this property an appealing option. Otherwise, spend your evenings in Commerce at Newly re-listed downtown historic apartment. Make the most of a fireplace, internet access and more here.
Where can I find cheap hotels in Commerce?
At Travelocity you’ll find really nice hotels in Commerce at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Commerce rather than in Commerce. We may find you even better rates, too.
How do I find the best Commerce hotel deals?
Simple! On Travelocity, look through the fantastic offers we’ve already found in Commerce then use our filters to find a great deal that’s perfect for you. Enter your travel dates, select the number of rooms you need, and we’ll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Commerce?
The cheapest hotel in Commerce is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel’s location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Commerce?
There are 81 hotels in Commerce on Travelocity.
What are the best hotels in Commerce?
Commerce has so many great hotels to choose from at Travelocity — and it’s so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Commerce for you!
When is the best time to visit Commerce?
If you want the joy of a fun-filled trip in peak season, visit Commerce during May, July and August. If you’d prefer the peace of off-season, book a stay during quieter months, such as January, October and December.
When is the cheapest time to stay in Commerce?
Based on historic data is usually the cheapest month to visit Commerce. However, we have incredible deals all year round, so we’re confident you’ll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Commerce?
There are multiple hotels in Commerce that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We’ve got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Commerce. We have plenty of kid-friendly hotels in Commerce to choose from on Travelocity!
Why book a hotel in Commerce through Travelocity?
Because we have the top hotels in Commerce! We want to help you travel more and worry less. That’s why we’ve put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you’re getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Commerce on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Commerce hotel reviews by fellow wanderers