Book Hotels in Commerce, MO
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Top Commerce hotels

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jul 27 to Jul 28
$105 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
"Very nice to stay in a brand new hotel. So clean. Everyone seemed very nice and helpful. Love the extra games and pool table to keep the kids busy. Loved that you had cookies and milk although we didn't make it down for that. I thought it was a wonderful idea."
Reviewed on Jul 11, 2025

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Jul 27 to Jul 28
$124 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Very clean and great customer service."
Reviewed on Jul 14, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jul 27 to Jul 28
$102 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great stay
"Awesome hotel. Beds are comfortable. Rooms are quiet. Breakfast was awesome."
Reviewed on Jul 13, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $117 total per night from Jul 27 to Jul 28
$117 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Staff was kind and accommodating."
Reviewed on Jul 16, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
$101 nightly
The price is $114 total per night from Aug 8 to Aug 9
$114 total
Aug 8 - Aug 9
Total includes taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"No Complaints"
Reviewed on Jul 11, 2025

The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Jul 20 to Jul 21
$132 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a casino and 2 restaurants. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public ...
The comfort I needed
"I accidentally booked the with day. The gentleman at the from desk was very patient helping me get it rebooked. The room was so spacious. Lived having my a thermostat with a quiet HVAC unit. Very modern and very quiet room."
Reviewed on Jul 14, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $102 total per night from Jul 27 to Jul 28
$102 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Hotel was clean. Large dining area. Was able to accommodate our large group"
Reviewed on Jul 14, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 21 to Jul 22
$79 total
Jul 21 - Jul 22
Total includes taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
Nice One-Night Stay
"Stopped in in late June. One night stay. Rooms was fine. Bed was comfy and pillows were good. The 'continental' breakfast was severely lacking."
Reviewed on Jul 6, 2025

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Jul 20 to Jul 21
$76 total
Jul 20 - Jul 21
Total includes taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
"This was the second stay in a weeks time. Different room but the bed still squeaked, same as the room across the hall. My husband thinks it is the bedframe when you sit on the bed or stand from it. Otherwise quite comfortable"
Reviewed on Jul 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Commerce hotel reviews by fellow wanderers

Candlewood Suites Cape Girardeau by IHG
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Room was lovely. Air con very cold and loud "
A verified traveler stayed at Candlewood Suites Cape Girardeau by IHG
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An Attraction
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