Book Hotels in Center, MO

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Top Center hotels

MTL HUNTING LAYAWAY & OUTDOOR HANGOUT

MTL HUNTING LAYAWAY & OUTDOOR HANGOUT

Center MO
$189 nightly
The price is $200 total per night from Feb 3 to Feb 4
$200 total
Feb 3 - Feb 4
Total with taxes and fees
A water park and an outdoor pool are featured at this smoke-free apartment. Families will appreciate the playground and barbecue grills.
Very nice and clean! So cozy and was perfect for our weekend at the lake!

Reviewed on Aug 31, 2025

Opens in a new windowMTL HUNTING LAYAWAY & OUTDOOR HANGOUT
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
Fully refundable
$93 nightly
The price is $107 total per night from Feb 8 to Feb 9
$107 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Parking was great and the front desk lady was very friendly and helpful.

Reviewed on Jan 4, 2026

Opens in a new windowSleep Inn & Suites Hannibal West
WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE

WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE

Center MO
This cabin features a water park, a garden, and barbecue grills.
We had a great time. Plenty of space, clean, nice outdoor areas. Would recommend.

Reviewed on Oct 28, 2025

Opens in a new windowWELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $116 total per night from Jan 20 to Jan 21
$116 total
Jan 20 - Jan 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal ...
Pool was perfect

Reviewed on Jan 7, 2026

Opens in a new windowBest Western On The River
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $202 total per night from Jan 15 to Jan 16
$202 total
Jan 15 - Jan 16
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning is also provided.
Average room

Reviewed on Dec 17, 2025

Opens in a new windowLighthouse Inn & Suites
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $90 total per night from Jan 25 to Jan 26
$90 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
All good, except a slight odor in the room

Reviewed on Jan 13, 2026

Opens in a new windowQuality Inn & Suites Hannibal West
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from Jan 20 to Jan 21
$90 total
Jan 20 - Jan 21
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Room was spacious and very clean. Bed comfortable. Breakfast was great! Staff friendly and helpful.

Reviewed on Jan 8, 2026

Opens in a new windowComfort Inn & Suites - Hannibal
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Jan 16 to Jan 17
$66 total
Jan 16 - Jan 17
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this motel's amenities. WiFi in public areas is free. A snack bar/deli and a fireplace in ...
Staff was very friendly and courteous. I will go back there in the future.

Reviewed on Dec 25, 2025

Opens in a new windowMotel 6 Hannibal, MO
Spacious 3-bedroom on a 140 acre working farm minutes from mark twain lake.

Spacious 3-bedroom on a 140 acre working farm minutes from mark twain lake.

2 out of 5
Center MO
$286 nightly
The price is $286 total per night from Jan 15 to Jan 16
$286 total
Jan 15 - Jan 16
Total with taxes and fees
This apartment features a water park and barbecue grills.
Opens in a new windowSpacious 3-bedroom on a 140 acre working farm minutes from mark twain lake.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Center?
From well-designed amenities to larger rooms, kid-friendly hotels come with features that can help turn a great family vacation into a fabulous one. These Center options make vacationing with children a piece of cake: WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE will help make your next trip the best one yet. It offers a host of nice little touches, such as a water park and animal viewing activities. Also check out the deals at Mark Twain lake getaway at Blue Lagoon!. It offers a firepit, pet-friendly facilities and ample opportunities for family time.
Where can I find cheap hotels in Center?
At Travelocity you'll find really nice hotels in Center at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Center rather than in Center. We may find you even better rates, too.
How do I find the best Center hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Center then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Center?
The cheapest hotel in Center is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Center?
There are 101 hotels in Center on Travelocity.
What are the best hotels in Center?
Center has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Center for you!
When is the best time to visit Center?
If you want the joy of a fun-filled trip in peak season, visit Center during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Center?
Based on historic data is usually the cheapest month to visit Center. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Center?
There are multiple hotels in Center that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Center. We have plenty of kid-friendly hotels in Center to choose from on Travelocity!
Why book a hotel in Center through Travelocity?
Because we have the top hotels in Center! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Center on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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