Book Hotels in Northwest Alabama, AL
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Top Northwest Alabama hotels

Holiday Inn Guin by IHG
5750 Highway 44, Guin, AL
Fully refundable
$111 nightly
The price is $127 total per night from Oct 12 to Oct 13
$127 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Parking was easy, even with a trailer. Was in town for Muleday as a vendor."
Reviewed on Oct 2, 2025

Renaissance Shoals Resort and Spa
10 Hightower Place, Florence, AL
Fully refundableReserve now, pay when you stay
$259 nightly
The price is $298 total per night from Nov 2 to Nov 3
$298 total
Nov 2 - Nov 3
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, express ...
"Great stay!"
Reviewed on Sep 24, 2025

The ColdWater Inn
712 Hwy 72 W, Tuscumbia, AL
$77 nightly
The price is $86 total per night from Oct 14 to Oct 15
$86 total
Oct 14 - Oct 15
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Beautiful property! Delicious hot breakfast."
Reviewed on Oct 2, 2025

The Stricklin Hotel
317 N Court St, Florence, AL
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $218 total per night from Oct 9 to Oct 10
$218 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
"A very unique place, formerly a retail space, converted to a hotel. The rooms decor reflects its history nicely! Staff was friendly, and we had cooffee and a breakfast snack at"
Reviewed on Oct 4, 2025

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
180 Etta Gray Street, Florence, AL
Fully refundable
$138 nightly
The price is $159 total per night from Oct 26 to Oct 27
$159 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Nice and quiet"
Reviewed on Sep 21, 2025

Days Inn by Wyndham Muscle Shoals Florence
2701 Woodward Ave, Muscle Shoals, AL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Oct 14 to Oct 15
$76 total
Oct 14 - Oct 15
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
"Rooms are very nice Clean spacious and comfortable. Office staff were difficult to deal with at first but were very hospitable by the time I left. I will go back there next time I’m in the area"
Reviewed on Oct 4, 2025

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Oct 14 to Oct 15
$75 total
Oct 14 - Oct 15
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"The staff was amazing and the rooms were VERY clean! The beds could be a little more comfortable but all in all it was a good experience."
Reviewed on Oct 4, 2025

Clarion Inn Sheffield Muscle Shoals
4900 Hatch Blvd, Sheffield, AL
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $91 total per night from Oct 14 to Oct 15
$91 total
Oct 14 - Oct 15
Total with taxes and fees
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Pet friendly"
Reviewed on Sep 25, 2025

Baymont by Wyndham Florence/Muscle Shoals
115 Ana Drive, Florence, AL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Oct 9 to Oct 10
$78 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
"Clean rooms"
Reviewed on Sep 14, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Northwest Alabama hotels

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E, Tuscumbia, AL
$67 nightly
The price is $75 total per night from Oct 14 to Oct 15
$75 total
Oct 14 - Oct 15
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Northwest Alabama with star-rating
Check Northwest Alabama Hotels by Star Rating

4 Star Hotels
2 properties
Recent Northwest Alabama hotel reviews by fellow wanderers

The Stricklin Hotel
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Awesome stay. Amazing historical area! Rooms were clean and updated "
A verified traveler from Nashville stayed at The Stricklin Hotel
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- Flights from Northwest Alabama Regional
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