Explore top 2026 5 Star Hotels in La Mesa

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Top La Mesa 5 Star hotels

Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
$342 nightly
The price is $397 total per night from Jun 14 to Jun 15
$397 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,000 reviews)
"Cathy In concierge was exceptional."

Reviewed on May 11, 2026

Opens in a new windowPendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

5 out of 5
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $287 total per night from Jun 4 to Jun 5
$287 total
Jun 4 - Jun 5
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,000 reviews)
"Loooooved the stay was great. Staff was on top Of my wishes and super respectful"

Reviewed on May 18, 2026

Opens in a new windowThe US Grant, a Luxury Collection Hotel, San Diego
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
5300 Grand Del Mar Court San Diego CA
Fully refundableReserve now, pay when you stay
$469 nightly
The price is $540 total per night from May 21 to May 22
$540 total
May 21 - May 22
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 6 restaurants. There's fun for all ages with a children's club and a children's pool, and babysitting ...
9.4/10 Exceptional! (978 reviews)
"Unforgettable time at Fairmont. From the moment you walk in, to the moment you leave; the red carpet never leaves your feet."

Reviewed on May 18, 2026

Opens in a new windowFairmont Grand Del Mar
The Lodge at Torrey Pines

The Lodge at Torrey Pines

5 out of 5
11480 N Torrey Pines Rd La Jolla CA
Fully refundableReserve now, pay when you stay
$589 nightly
The price is $678 total per night from May 25 to May 26
$678 total
May 25 - May 26
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
9.4/10 Exceptional! (934 reviews)
"We had a good overall stay at the lodge"

Reviewed on May 2, 2026

Opens in a new windowThe Lodge at Torrey Pines
L'Auberge Del Mar

L'Auberge Del Mar

5 out of 5
1540 Camino Del Mar Del Mar CA
Fully refundableReserve now, pay when you stay
$495 nightly
The price is $560 total per night from May 25 to May 26
$560 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel features a full-service spa, 2 outdoor tennis courts, and a restaurant. Traveling on business? Take advantage of the free WiFi in public ...
8.8/10 Excellent! (859 reviews)
"Most friendly and accommodating staff I have experienced. Daily evening music in the living room was exceptional."

Reviewed on May 8, 2026

Opens in a new windowL'Auberge Del Mar
Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
$812 nightly
The price is $901 total per night from May 26 to May 27
$901 total
May 26 - May 27
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (149 reviews)
"Perfect view of the ocean! The room was very clean! The grounds are absolutely beautiful!"

Reviewed on May 15, 2026

Opens in a new windowShore House at The Del, LXR Hotels & Resorts
The Bower Coronado

The Bower Coronado

5 out of 5
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $385 total per night from May 25 to May 26
$385 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (234 reviews)
"Do not stay here! This property is listed as a 5 star hotel but don’t let the aesthetic fool you. Yes, the rooms are visually pleasing however they are very small. The hotel is understaffed. They have one attendant running around doing valet, bag assistance, even at times cleaning the rooms, which ..."

Reviewed on May 19, 2026

Opens in a new windowThe Bower Coronado
Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
$952 nightly
The price is $1,047 total per night from May 26 to May 27
$1,047 total
May 26 - May 27
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9.2/10 Wonderful! (135 reviews)
"Ocean view and breeze in the balcony were just what we needed."

Reviewed on May 16, 2026

Opens in a new windowBeach Village at The Del, LXR Hotels & Resorts
Rancho Valencia Resort and Spa

Rancho Valencia Resort and Spa

5 out of 5
5921 Valencia Circle Rancho Santa Fe CA
Fully refundableReserve now, pay when you stay
$1,324 nightly
The price is $1,432 total per night from Jun 10 to Jun 11
$1,432 total
Jun 10 - Jun 11
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury resort. Families will appreciate the playground, complimentary bicycles, ...
Opens in a new windowRancho Valencia Resort and Spa
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La Mesa Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in La Mesa to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. La Mesa 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in La Mesa before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent La Mesa hotel reviews by fellow wanderers