Explore top 2025 4 Star Hotels in Pickens

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Top Pickens 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
$297 nightly
The price is $327 total per night from Oct 26 to Oct 27
$327 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
9.4/10 Exceptional! (389 reviews)
"What a fabulous hotel. Great location, super clean, and the most helpful staff."

Reviewed on Sep 29, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
$189 nightly
The price is $210 total per night from Oct 19 to Oct 20
$210 total
Oct 19 - Oct 20
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
9.6/10 Exceptional! (690 reviews)
"Love this hotel - far superior than any other hotel in the area"

Reviewed on Sep 30, 2025

Opens in a new windowThe Shepherd Hotel Downtown Clemson
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St, Greenville, SC
$178 nightly
The price is $195 total per night from Nov 2 to Nov 3
$195 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,001 reviews)
"Very courteous and helpful staff"

Reviewed on Oct 4, 2025

Opens in a new windowThe Westin Poinsett Greenville
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr, Greenville, SC
$148 nightly
The price is $163 total per night from Oct 26 to Oct 27
$163 total
Oct 26 - Oct 27
Total with taxes and fees
A 24-hour gym is featured at this apartment, along with express check-in and express check-out. Laundry facilities are provided for your convenience.
9.2/10 Wonderful! (740 reviews)
"Parking a little bit tough. All else is great."

Reviewed on Sep 30, 2025

Opens in a new windowMint House Greenville - Downtown
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy, Clemson, SC
$179 nightly
The price is $199 total per night from Oct 15 to Oct 16
$199 total
Oct 15 - Oct 16
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
9.6/10 Exceptional! (544 reviews)
"Clean room, great staff, location and parking and the bartender"

Reviewed on Sep 28, 2025

Opens in a new windowThe Abernathy of Clemson
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
300 Hammett St, Greenville, SC
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A gym and a virtual front desk are also provided.
7.6/10 Good! (40 reviews)
"Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge."

Reviewed on Jun 19, 2025

Opens in a new windowPark Place Apartments by Landing
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd, Travelers Rest, SC
$273 nightly
The price is $301 total per night from Nov 5 to Nov 6
$301 total
Nov 5 - Nov 6
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (12 reviews)
"This is my third time staying at the station and it didn’t disappoint! I love the comfy beds and the green space around the rooms. What a beautiful area!"

Reviewed on Jul 26, 2025

Opens in a new windowThe Station by Compo Hotels
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4 out of 5
621 S Mechanic St, Pendleton, SC
$178 nightly
The price is $198 total per night from Oct 15 to Oct 16
$198 total
Oct 15 - Oct 16
Total with taxes and fees
This bed & breakfast features free WiFi in public areas, concierge services, and free self parking. Enjoy the free full breakfast each morning. A garden, express ...
9.8/10 Exceptional! (74 reviews)
"Excellent property with spacious rooms and a great front porch with rocking chairs to relax in. Fabulous breakfast every day. But most important was the staff. Angela and Micheal were very welcoming and ready to help with anything you might need. Would definitely return."

Reviewed on Sep 2, 2025

Opens in a new windowLiberty Hall Bed and Breakfast
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines, Travelers Rest, SC
$459 nightly
The price is $505 total per night from Oct 29 to Oct 30
$505 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
9.6/10 Exceptional! (30 reviews)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."

Reviewed on Jul 27, 2025

Opens in a new windowHotel Domestique
Tuxedo Falls

Tuxedo Falls

4 out of 5
100 Twin Creeks Rd, Zirconia, NC
Enjoy free WiFi, free parking, and a picnic area. Popular attractions Lake Summit and Connemara are located nearby.
10/10 Exceptional! (2 reviews)
"This is, by far, one of the greatest stays we have ever had! The cabin was brand new and was impeccable from the bathroom to the living space, to the pizza grill. The mini kitchenette was stocked with everything we would need, including beautiful local pottery and glassware. The porch was so spacious, ..."

Reviewed on Jul 27, 2025

Opens in a new windowTuxedo Falls
Don't see what you're looking for?
See all available properties in Pickens
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Pickens

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Pickens 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Pickens will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Pickens, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Pickens hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity