Explore top 2026 4 Star Hotels in Pickens

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Top Pickens 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
$342 nightly
The price is $375 total per night from May 21 to May 22
$375 total
May 21 - May 22
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.6/10 Exceptional! (480 reviews)
Clean room.

Reviewed on Apr 22, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
$272 nightly
The price is $299 total per night from May 10 to May 11
$299 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,000 reviews)
The front desk lady was very kind when I was asking questions about my booking! She was thorough and detailed and didn’t rush when explaining things to me. I appreciated her patience! The room was clean and my view was nice too!

Reviewed on Apr 17, 2026

Opens in a new windowThe Westin Poinsett Greenville
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $203 total per night from May 17 to May 18
$203 total
May 17 - May 18
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
9.8/10 Exceptional! (791 reviews)
perfection!

Reviewed on Apr 23, 2026

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
$105 nightly
The price is $115 total per night from May 18 to May 19
$115 total
May 18 - May 19
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this apartment. Express check-in and express check-out are also provided.
9.2/10 Wonderful! (815 reviews)
Spacious apartment, w/ high ceilings, full size kitchen and laundry. Comes with dishes, pots, pans, full size fridge. Less than a mile to anything downtown. Great location. Very secure check in with keyed building access. Very clean and super comfy bed!

Reviewed on Apr 23, 2026

Opens in a new windowMint House Greenville Downtown by Kasa
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
$166 nightly
The price is $184 total per night from May 11 to May 12
$184 total
May 11 - May 12
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
9.6/10 Exceptional! (592 reviews)
Easy parking, great location. Will stay there again

Reviewed on Apr 24, 2026

Opens in a new windowThe Abernathy of Clemson
The Station by Compo Hotels

The Station by Compo Hotels

4 out of 5
745 Old Buncombe Rd Travelers Rest SC
$350 nightly
The price is $385 total per night from Apr 27 to Apr 28
$385 total
Apr 27 - Apr 28
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Barbecue grills are provided for your convenience.
10/10 Exceptional! (19 reviews)
Swamp rabbit trail and restaurants very close

Reviewed on Apr 2, 2026

Opens in a new windowThe Station by Compo Hotels
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4 out of 5
621 S Mechanic St Pendleton SC
$159 nightly
The price is $176 total per night from May 9 to May 10
$176 total
May 9 - May 10
Total with taxes and fees
This bed & breakfast features free WiFi in public areas, concierge services, and free self parking. Enjoy the free full breakfast each morning. A garden, express ...
10/10 Exceptional! (87 reviews)
The property is curated to perfection. The gardens, the living areas, everything. The host, Angela, is so nice, friendly and kind. The room was decorated nicely. The phone chargers, the sound machine! Love! The breakfast was amazing. I needed a reset and this gave it to me.

Reviewed on Mar 27, 2026

Opens in a new windowLiberty Hall Bed and Breakfast
Hotel Domestique

Hotel Domestique

4 out of 5
10 Road of Vines Travelers Rest SC
$409 nightly
The price is $450 total per night from May 18 to May 19
$450 total
May 18 - May 19
Total with taxes and fees
This hotel features a restaurant, an outdoor tennis court, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like cooked-to-order breakfast and ...
Opens in a new windowHotel Domestique
Tuxedo Falls

Tuxedo Falls

4 out of 5
100 Twin Creeks Rd Zirconia NC
Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Lake Summit and Connemara are located nearby.
10/10 Exceptional! (3 reviews)
This is, by far, one of the greatest stays we have ever had! The cabin was brand new and was impeccable from the bathroom to the living space, to the pizza grill. The mini kitchenette was stocked with everything we would need, including beautiful local pottery and glassware. The porch was so spacious, ...

Reviewed on Jul 27, 2025

Opens in a new windowTuxedo Falls
Luxe Keowee Key Living: Golf Views & Resort Pool

Luxe Keowee Key Living: Golf Views & Resort Pool

4 out of 5
Salem SC
A marina and an outdoor pool are featured at this smoke-free apartment. Business travelers can take advantage of the free WiFi in public areas. Take advantage ...
Opens in a new windowLuxe Keowee Key Living: Golf Views & Resort Pool
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4 Star Hotels Pickens

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Pickens 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Pickens will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Pickens, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Pickens hotel reviews by fellow wanderers