Explore top 2026 4 Star Hotels in Opelousas

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Top Opelousas 4 Star hotels

DoubleTree by Hilton Hotel Lafayette

DoubleTree by Hilton Hotel Lafayette

4 out of 5
1521 W Pinhook Rd Lafayette LA
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jul 9 to Jul 10
$97 total
Jul 9 - Jul 10
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center, free ...
8.6/10 Excellent! (1,023 reviews)
"Used as a overnight stay before a flight out. Hotel is always clean and staff is nice. We ate at 337 and bartender was great. Food was delicious."

Reviewed on Jun 10, 2026

Opens in a new windowDoubleTree by Hilton Hotel Lafayette
Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes

4 out of 5
509 Highland Park Ln Lafayette LA
$236 nightly
The price is $257 total per night from Jun 14 to Jun 15
$257 total
Jun 14 - Jun 15
Total with taxes and fees
This vacation home featured laundry facilities and a virtual front desk. Take advantage of the free self parking.
Opens in a new windowEnclave 3 Bedroom Luxury Homes
Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages

4 out of 5
8450 Roberts Cove Road Rayne LA
$195 nightly
The price is $221 total per night from Jun 14 to Jun 15
$221 total
Jun 14 - Jun 15
Total with taxes and fees
This cottage features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free full breakfast each morning. A garden and wedding services ...
9.6/10 Exceptional! (97 reviews)
"Delightful bed and breakfast venue. Real Southern charm and Lynn (the owner) was a fantastic host. Far exceeded our expectations and genuinely wished we could have stayed longer."

Reviewed on Apr 29, 2026

Opens in a new windowMaison D'Memoire Bed & Breakfast Cottages
Canal Inn

Canal Inn

4 out of 5
221 East Spring St Lafayette LA
This vacation home features laundry facilities. Take advantage of the free self parking.
Opens in a new windowCanal Inn
Esplanade Inn

Esplanade Inn

4 out of 5
217 E Spring St Lafayette LA
$215 nightly
The price is $234 total per night from Jun 15 to Jun 16
$234 total
Jun 15 - Jun 16
Total with taxes and fees
This vacation home features laundry facilities. Take advantage of the free self parking.
Opens in a new windowEsplanade Inn
Canal Inn

Canal Inn

4 out of 5
221 E Spring St Lafayette LA
This vacation home features laundry facilities. Take advantage of the free self parking.
Opens in a new windowCanal Inn
Poydras Inn

Poydras Inn

4 out of 5
215 E Spring St Lafayette LA
$217 nightly
The price is $237 total per night from Jun 14 to Jun 15
$237 total
Jun 14 - Jun 15
Total with taxes and fees
This vacation home features laundry facilities. Take advantage of the free self parking.
Opens in a new windowPoydras Inn
The Royal Inn

The Royal Inn

4 out of 5
223 E Spring St Lafayette LA
$234 nightly
The price is $255 total per night from Jun 14 to Jun 15
$255 total
Jun 14 - Jun 15
Total with taxes and fees
This vacation home features laundry facilities. Take advantage of the free self parking.
Opens in a new windowThe Royal Inn
Decatur Inn

Decatur Inn

4 out of 5
218 Rose St Lafayette LA
$241 nightly
The price is $263 total per night from Jun 14 to Jun 15
$263 total
Jun 14 - Jun 15
Total with taxes and fees
This vacation home features a virtual front desk. Take advantage of the free self parking.
Opens in a new windowDecatur Inn
Wyndham Garden Lafayette

Wyndham Garden Lafayette

4 out of 5
1801 W Pinhook Road Lafayette LA
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
5.4/10 (548 reviews)
"It is convenient to many eateries and shopping. Only drawback is it is on lasted on an extremely busy road. Often hard to get out."

Reviewed on Dec 19, 2020

Opens in a new windowWyndham Garden Lafayette
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4 Star Hotels Opelousas

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Opelousas 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Opelousas will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Opelousas, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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