Hotels on the Lake in Upstate South Carolina from $63
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Top Upstate South Carolina Hotels on the Lake

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
This vacation home features a garden, laundry facilities, and barbecue grills. There's fun for all ages with a playground and an arcade/game room.

Relax on the shore of Lake Hartwell in our Fair Play retreat
A water park and a hot tub are featured at this smoke-free vacation home. A garden, a computer station, and laundry facilities are also on offer.

Clemson University's James F. Martin Inn
240 Madren Center Drive, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
$149 nightly
The price is $165 total per night
$165 total
Oct 5 - Oct 6
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
$121 nightly
The price is $133 total per night
$133 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Fall fun at the cabin! Convenient to Lake Keowee and Clemson
A gym is featured at this cabin, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.

Hampton Inn Clemson-University Area
851 Tiger Blvd, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $122 total per night
$122 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

Best Western Seneca-Clemson
511 Bypass Highway 123, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $98 total per night
$98 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $75 total per night
$75 total
Oct 5 - Oct 6
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...

Days Inn by Wyndham Clemson
1387 Tiger Blvd, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $94 total per night
$94 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Studio 6 Greenville, SC - I-85 Near Downtown
12 Impact Dr, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
$57 nightly
The price is $63 total per night
$63 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities and barbecue grills are also provided.
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Upstate South Carolina hotels essential information
Accommodation | 2,856 hotels |
---|---|
Lowest Price | $63 |
Highest Price | $165 |
Popular hotels | Relax on the shore of Lake Hartwell in our Fair Play retreat, 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks, Clemson University's James F. Martin Inn, Hampton Inn & Suites Seneca-Clemson Area, Best Western Seneca-Clemson, Days Inn by Wyndham Seneca / Clemson Area, Fall fun at the cabin! Convenient to Lake Keowee and Clemson, Hampton Inn Clemson-University Area, Days Inn by Wyndham Clemson, Studio 6 Greenville, SC - I-85 Near Downtown |
Recent Upstate South Carolina hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Greenville Haywood
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean room, nice staff, and convenient location. "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Greenville Haywood
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