Explore 42 Luxury Hotels in Syracuse

Name: Collegian Hotel & Suites, Trademark Collection by Wyndham
Price range: $162 total

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Best Luxury Hotels in Syracuse

Mirbeau Inn and Spa

851 West Genesee Street Skaneateles NY

Fully refundableReserve now, pay when you stay

$530 nightly

$636 total

Aug 17 - Aug 18

Total with taxes and fees

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Business travelers can take advantage of the business center. Enjoy ...

9.6/10 Exceptional! (232 reviews)

"Everything was beautiful & relaxing. But steps into hot tub were too steep for person using a walker."

Reviewed on Jul 31, 2026

Marriott Syracuse Downtown

100 East Onondaga Street Syracuse NY

Fully refundableReserve now, pay when you stay

$209 nightly

$245 total

Aug 11 - Aug 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (1,001 reviews)

Reviewed on Aug 1, 2026

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

400 7th North St. North Syracuse NY

Fully refundable

$129 nightly

$148 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (1,001 reviews)

"hot tub was great"

Reviewed on Aug 1, 2026

Budget Inn - Syracuse Airport

901 S Bay Rd North Syracuse NY

Fully refundableReserve now, pay when you stay

$105 nightly

$121 total

Aug 3 - Aug 4

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area and a safe deposit box are also provided.

8.4/10 Very Good! (706 reviews)

"Room smelled horrible. And there were spiders in the bed"

Reviewed on Aug 1, 2026

Days Inn by Wyndham Liverpool/Syracuse

430 Electronics Pkwy Liverpool NY

Fully refundableReserve now, pay when you stay

$67 nightly

$77 total

Sep 1 - Sep 2

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and free ...

6/10 (521 reviews)

"This place is not clean"

Reviewed on Aug 1, 2026

Red Roof Inn Syracuse

6614 North Thompson Road Syracuse NY

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A snack ...

4.8/10 (15 reviews)

"We arrived and it was shut down. No notice or warning. I have sent in a refund request in but have not heard a word since. Expedia has failed me. Booked it through expedia. Expedia should have notified me the place had shutdown. Drove 500 miles with no place to stay. Not a good feeling to be left ..."

Reviewed on May 9, 2026

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Syracuse Inn

6620 Old Collamer Road East Syracuse NY

Fully refundableReserve now, pay when you stay

$68 nightly

$80 total

Aug 8 - Aug 9

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.

Collegian Hotel & Suites, Trademark Collection by Wyndham

1060 E Genesee St Syracuse NY

Fully refundableReserve now, pay when you stay

$139 nightly

$162 total

Aug 3 - Aug 4

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Syracuse

34 State

34 State St Skaneateles NY

$369 nightly

$443 total

Aug 4 - Aug 5

Total with taxes and fees

10/10 Exceptional! (27 reviews)

Syracuse Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Syracuse luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Syracuse to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Syracuse will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Syracuse, and plan your next opulent escape.

Syracuse hotels essential information

Accommodation	554 hotels
Lowest Price	$77
Highest Price	$636
Popular hotels	Mirbeau Inn and Spa, Marriott Syracuse Downtown, Syracuse Inn, Holiday Inn & Suites Syracuse Airport - Liverpool by IHG, Budget Inn - Syracuse Airport, Days Inn by Wyndham Liverpool/Syracuse, Collegian Hotel & Suites, Trademark Collection by Wyndham, Red Roof Inn Syracuse

Popular Luxury Stays in Syracuse

Recent Syracuse Hotel Reviews By Fellow Wanderers

Best Western The Inn At The Fairgrounds

5 out of 5

Posted less than an hour ago

Travelocity Verified Review

"The hotel was clean, the staff was very friendly and helpful, the owner checked on us. They had a wonderful restaurant on premises."

A verified traveler stayed at Best Western The Inn At The Fairgrounds

Comfort Inn - NYS Fairgrounds

4 out of 5

Posted 20 hours ago

Travelocity Verified Review

"Clean, good room. Got a reservation when rooms in the area were very difficult to find. The hotel is old and in need of some repairs, but the price was right and there were no problems at all. If you want five star luxury, this is not your place. The breakfast is a nice plus! Serves it's purpose very well."

A verified traveler stayed at Comfort Inn - NYS Fairgrounds

Marriott Syracuse Downtown

4 out of 5

Posted 1 day ago

Travelocity Verified Review

"A Beautifully Restored Historic Hotel in a Challenging Downtown Setting Pros - Stunning historic hotel beautifully renovated while preserving its 1920s character. - Impressive lobby and displays highlighting the building's history. - Friendly, professional staff. - Front desk quickly resolved a parking discrepancy and comped parking for the remainder of our stay. - Tastefully renovated room with microwave and fridge. - Comfortable bed. - Very good food and service at Shaughnessy's. - Sweet Praxis and Café Kubal are excellent breakfast options within walking distance. Cons - Ongoing construction made arrival confusing. - Valet podium was unattended when we arrived. - Parking can be difficult for first-time visitors; self-parking is in a garage across the street. - Room and bathroom were small by modern standards. - Downtown Syracuse has many vacant storefronts and visible homelessness that may make some guests uncomfortable, though we never felt threatened. - Eleven Waters was closed during our stay. Overall: The beautifully restored architecture, comfortable rooms, thoughtful amenities, and excellent staff make for a memorable stay. While the neighbourhood and parking situation present challenges, this remains one of the most distinctive places to stay in Syracuse. 4.5/5 stars. A beautifully restored historic hotel with excellent staff and character, somewhat offset by parking confusion, construction, and a downtown environment that may not appeal to everyone."

A verified traveler stayed at Marriott Syracuse Downtown