Explore 42 Luxury Hotels in Syracuse

Name: Collegian Hotel & Suites, Trademark Collection by Wyndham
Price range: $157 total

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Best Luxury Hotels in Syracuse

Marriott Syracuse Downtown

100 East Onondaga Street Syracuse NY

Fully refundableReserve now, pay when you stay

$142 nightly

$166 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (1,002 reviews)

"This hotel is so beautiful on the inside. It has amazing views outside the window and everyone here is friendly."

Reviewed on Oct 3, 2026

Days Inn by Wyndham Liverpool/Syracuse

430 Electronics Pkwy Liverpool NY

Fully refundableReserve now, pay when you stay

$64 nightly

$73 total

Oct 26 - Oct 27

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and free ...

6/10 (545 reviews)

"Mold in the coffee maker, be for real, amended like pee like the room have been used in a year."

Reviewed on Oct 2, 2026

Red Roof Inn Syracuse

6614 North Thompson Road Syracuse NY

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A snack ...

4.8/10 (15 reviews)

"We arrived and it was shut down. No notice or warning. I have sent in a refund request in but have not heard a word since. Expedia has failed me. Booked it through expedia. Expedia should have notified me the place had shutdown. Drove 500 miles with no place to stay. Not a good feeling to be left ..."

Reviewed on May 9, 2026

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Mirbeau Inn and Spa

851 West Genesee Street Skaneateles NY

Fully refundableReserve now, pay when you stay

$399 nightly

$479 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Business travelers can take advantage of the business center. Enjoy ...

Syracuse Inn

6620 Old Collamer Road East Syracuse NY

Fully refundableReserve now, pay when you stay

$59 nightly

$69 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

400 7th North St. North Syracuse NY

Fully refundable

$138 nightly

$159 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Budget Inn - Syracuse Airport

901 S Bay Rd North Syracuse NY

Fully refundableReserve now, pay when you stay

$85 nightly

$98 total

Nov 1 - Nov 2

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area and a safe deposit box are also provided.

Collegian Hotel & Suites, Trademark Collection by Wyndham

1060 E Genesee St Syracuse NY

Fully refundableReserve now, pay when you stay

$134 nightly

$157 total

Oct 18 - Oct 19

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Syracuse

34 State

34 State St Skaneateles NY

$403 nightly

$483 total

Oct 5 - Oct 6

Total with taxes and fees

10/10 Exceptional! (27 reviews)

Syracuse Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Syracuse luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Syracuse to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Syracuse will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Syracuse, and plan your next opulent escape.

Syracuse hotels essential information

Accommodation	540 hotels
Lowest Price	$69
Highest Price	$483
Popular hotels	Mirbeau Inn and Spa, Marriott Syracuse Downtown, Syracuse Inn, Holiday Inn & Suites Syracuse Airport - Liverpool by IHG, Budget Inn - Syracuse Airport, Days Inn by Wyndham Liverpool/Syracuse, Collegian Hotel & Suites, Trademark Collection by Wyndham, Red Roof Inn Syracuse