Explore 42 Luxury Hotels in Syracuse

Name: Collegian Hotel & Suites, Trademark Collection by Wyndham
Price range: $168 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Syracuse

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

400 7th North St. North Syracuse NY

Fully refundable

$137 nightly

$158 total

Oct 12 - Oct 13

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (1,002 reviews)

"The staff was very nice and helpful. Great having a restaurant on site- not much else around. Carpet is old but everything is clean and spacious. Airport shuttle is quick and efficient- driver was very nice."

Reviewed on Sep 11, 2026

Red Roof Inn Syracuse

6614 North Thompson Road Syracuse NY

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A snack ...

4.8/10 (15 reviews)

"We arrived and it was shut down. No notice or warning. I have sent in a refund request in but have not heard a word since. Expedia has failed me. Booked it through expedia. Expedia should have notified me the place had shutdown. Drove 500 miles with no place to stay. Not a good feeling to be left ..."

Reviewed on May 9, 2026

Get rates

Mirbeau Inn and Spa

851 West Genesee Street Skaneateles NY

Fully refundableReserve now, pay when you stay

$530 nightly

$636 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Business travelers can take advantage of the business center. Enjoy ...

Marriott Syracuse Downtown

100 East Onondaga Street Syracuse NY

Fully refundableReserve now, pay when you stay

$159 nightly

$186 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Syracuse Inn

6620 Old Collamer Road East Syracuse NY

Fully refundableReserve now, pay when you stay

$60 nightly

$71 total

Oct 11 - Oct 12

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.

Budget Inn - Syracuse Airport

901 S Bay Rd North Syracuse NY

Fully refundableReserve now, pay when you stay

$95 nightly

$109 total

Sep 13 - Sep 14

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area and a safe deposit box are also provided.

Days Inn by Wyndham Liverpool/Syracuse

430 Electronics Pkwy Liverpool NY

Fully refundableReserve now, pay when you stay

$68 nightly

$79 total

Oct 5 - Oct 6

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and free ...

Collegian Hotel & Suites, Trademark Collection by Wyndham

1060 E Genesee St Syracuse NY

Fully refundableReserve now, pay when you stay

$143 nightly

$168 total

Oct 4 - Oct 5

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport ...

Don't see what you're looking for?

See all available properties in Syracuse

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Syracuse

34 State

34 State St Skaneateles NY

$369 nightly

$443 total

Sep 14 - Sep 15

Total with taxes and fees

10/10 Exceptional! (27 reviews)

Syracuse Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Syracuse luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Syracuse to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Syracuse will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Syracuse, and plan your next opulent escape.

Syracuse hotels essential information

Accommodation	544 hotels
Lowest Price	$71
Highest Price	$636
Popular hotels	Mirbeau Inn and Spa, Marriott Syracuse Downtown, Syracuse Inn, Holiday Inn & Suites Syracuse Airport - Liverpool by IHG, Budget Inn - Syracuse Airport, Days Inn by Wyndham Liverpool/Syracuse, Collegian Hotel & Suites, Trademark Collection by Wyndham, Red Roof Inn Syracuse