Explore 42 Luxury Hotels in Syracuse

Name: Mirbeau Inn and Spa
Price range: $540 total

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Best Luxury Hotels in Syracuse

Marriott Syracuse Downtown

100 East Onondaga Street Syracuse NY

Fully refundableReserve now, pay when you stay

$159 nightly

$186 total

May 31 - Jun 1

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (1,006 reviews)

"Muy buen hotel,excelente servicio y las personas muy amables,lo volveré a visitar."

Reviewed on May 25, 2026

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

400 7th North St. North Syracuse NY

Fully refundable

$134 nightly

$154 total

May 31 - Jun 1

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (1,001 reviews)

"There were multiple stains on the ceiling. Paid for a room with small kitchen however there were no utensils cups or glasses. Had to request cleaning as they missed two days of refreshing towels and taking out trash. Disappointed as prices were high due to multiple college graduation but inexcusable ..."

Reviewed on May 16, 2026

Budget Inn - Syracuse Airport

901 S Bay Rd North Syracuse NY

Fully refundableReserve now, pay when you stay

$95 nightly

$109 total

May 27 - May 28

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area and a safe deposit box are also provided.

8.4/10 Very Good! (692 reviews)

"Staff friendly and inviting...room and bathroom was clean...room was cleaned and beds made daily."

Reviewed on May 11, 2026

Collegian Hotel & Suites, Trademark Collection by Wyndham

1060 E Genesee St Syracuse NY

Fully refundableReserve now, pay when you stay

$149 nightly

$174 total

May 30 - May 31

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

7.6/10 Good! (1,002 reviews)

"One of the worst stays! A/c was not working while the room temp was 86 degrees. It was terrible to sleep thru the night on such a hot room. Room windows are not operable so was stuck in that 120 sq.ft. stuffy room. Restaurant was not open the two days we stayed here so no food available either. Bathroom ..."

Reviewed on May 20, 2026

Syracuse Inn

6620 Old Collamer Road East Syracuse NY

Fully refundableReserve now, pay when you stay

$63 nightly

$74 total

May 27 - May 28

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.

6.6/10 (433 reviews)

"The room was dirty and funky"

Reviewed on May 25, 2026

Days Inn by Wyndham Liverpool/Syracuse

430 Electronics Pkwy Liverpool NY

Fully refundableReserve now, pay when you stay

$71 nightly

$82 total

May 27 - May 28

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and free ...

6/10 (499 reviews)

"We booked a room for graduation weekend. We left with no where to go within 30 minutes. This place was the dirty, smelly and poorly maintained. The room stunk like a hot boxed ash tray. You can tell one dirty rag was used to wipe all the surfaces. Almost everything was broken including the lock on ..."

Reviewed on May 18, 2026

Red Roof Inn Syracuse

6614 North Thompson Road Syracuse NY

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A snack ...

4.8/10 (15 reviews)

"We arrived and it was shut down. No notice or warning. I have sent in a refund request in but have not heard a word since. Expedia has failed me. Booked it through expedia. Expedia should have notified me the place had shutdown. Drove 500 miles with no place to stay. Not a good feeling to be left ..."

Reviewed on May 9, 2026

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Mirbeau Inn and Spa

851 West Genesee Street Skaneateles NY

$450 nightly

$540 total

May 27 - May 28

Total with taxes and fees

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Business travelers can take advantage of the business center. Enjoy ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Syracuse

34 State

34 State St Skaneateles NY

$369 nightly

$443 total

May 27 - May 28

Total with taxes and fees

Syracuse Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Syracuse luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Syracuse to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Syracuse will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Syracuse, and plan your next opulent escape.

Syracuse hotels essential information

Accommodation	540 hotels
Lowest Price	$74
Highest Price	$540
Popular hotels	Mirbeau Inn and Spa, Marriott Syracuse Downtown, Syracuse Inn, Holiday Inn & Suites Syracuse Airport - Liverpool by IHG, Budget Inn - Syracuse Airport, Days Inn by Wyndham Liverpool/Syracuse, Collegian Hotel & Suites, Trademark Collection by Wyndham, Red Roof Inn Syracuse

Popular Luxury Stays in Syracuse

Recent Syracuse Hotel Reviews By Fellow Wanderers

Days Inn by Wyndham Syracuse

5 out of 5

Posted 3 hours ago

Travelocity Verified Review

"Nothing but good with this place very comfortable and the night desk worker was such a beautiful person so nice"

A verified traveler stayed at Days Inn by Wyndham Syracuse

Hampton Inn & Suites Syracuse Dewitt

4 out of 5

Posted 1 day ago

Travelocity Verified Review

"First the cons...then the pros :) The hotel was nice and clean and our room was very spacious and I loved that! However, the AC in our room was not working well...it "worked" but we had to have it at 61 F to have the room "cool" it was not cold at all as we should be freezing if it was really 61 F but all the rooms were booked so we couldn't change rooms and its always a pain to change rooms, the sink faucet handle was broken so if you lifted it too hard it came off lol, and the desk chair was broken too, it was leaning sideways and there was a sofa in our room so we just sat on that...other than those 3 things, the room was very clean...the bed and pillows were VERY comfortable and the dark-out curtains were really nice. The iron/ironing board and the hair dryer both worked well too. Oh they had yummy chocolate chip cookies one night for guests by the front desk and that was a nice treat :)"

A verified traveler stayed at Hampton Inn & Suites Syracuse Dewitt