Explore 80 Luxury Hotels in Southwestern Virginia

Name: Ramada by Wyndham Wytheville
Price range: $69 total
Rating: 7.8

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Best Luxury Hotels in Southwestern Virginia

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton

110 Shenandoah Ave Ne Roanoke VA

Fully refundableReserve now, pay when you stay

$193 nightly

$218 total

Oct 25 - Oct 26

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.6/10 Exceptional! (1,005 reviews)

"History is amazing."

Reviewed on Oct 11, 2026

Motel 6 Hillsville, VA

57 Airport Road Hillsville VA

Fully refundable

$60 nightly

$68 total

Oct 12 - Oct 13

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A business center, a snack bar/deli, and laundry facilities are also on ...

8.4/10 Very Good! (1,002 reviews)

"The room itself was clean and well maintained, but one bedside light didn’t work and neither did the bedside phone charging station. Staff was friendly enough. The room was very loud - from outside road traffic to the thin, popping walls to the terrible noise from the room above us. So loud that ..."

Reviewed on Oct 11, 2026

SureStay Hotel by Best Western Christiansburg Blacksburg

Ponderosa Drive, 135 Christiansburg VA

Fully refundableReserve now, pay when you stay

$76 nightly

$87 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

8.2/10 Very Good! (1,002 reviews)

"Room just felt unclean and my feet were sticky after walking in the room. Breakfast is ok and staff was fine but the lady who checked us in seemed annoyed we were there."

Reviewed on Oct 11, 2026

Natural Bridge Hotel, Trademark Collection by Wyndham

15 Appledore Ln Natural Bridge VA

Fully refundableReserve now, pay when you stay

$89 nightly

$103 total

Oct 12 - Oct 13

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 5 conference rooms, along with free WiFi in public areas. ...

7.8/10 Good! (1,000 reviews)

"Should be cleaner and include breakfast as this is one of the more expensive hotels in the area. The elevator needs an update too, seemed a bit sketchy."

Reviewed on Oct 9, 2026

Ramada by Wyndham Wytheville

955 Peppers Ferry Rd Wytheville VA

Fully refundableReserve now, pay when you stay

$60 nightly

$69 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

7.8/10 Good! (1,588 reviews)

"The bed was very comfortable but the light by the mirror and sink did not work. The bathroom exhaust fan did not work. The chair at the desk was not functional as it was bent out of shape. The staff was very friendly, however. The hotel is trying to get back on its feet but isn't quite there ..."

Reviewed on Oct 10, 2026

Super 8 by Wyndham Radford VA

1600 Tyler Ave Radford VA

Fully refundableReserve now, pay when you stay

$55 nightly

$63 total

Oct 18 - Oct 19

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...

7.6/10 Good! (1,001 reviews)

"The facility was perfectly cromulent for a football game weekend with most other locations fully booked and at extremely high prices. Would do again for a football weekend"

Reviewed on Oct 9, 2026

Travel Lite Motel

655 East Main Street Wytheville VA

Fully refundableReserve now, pay when you stay

$66 nightly

$76 total

Oct 12 - Oct 13

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...

7.2/10 Good! (186 reviews)

"Strong smells, wooden floor feels like walking on a water bed, ac blows hot air, tv is very tiny and can't hookyou game system up, funiture sticky with stains, beds don't look refreshed, door had openings at the bottom for bugs from outside to come in, dont book in whytheville, if you do pay in person, ..."

Reviewed on Oct 4, 2026

Motel 6 Bristol, VA

21561 Clear Creek Rd Bristol VA

Fully refundableReserve now, pay when you stay

$75 nightly

$84 total

Oct 12 - Oct 13

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A business center, a snack bar/deli, and laundry facilities are also on ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Southwestern Virginia

The Martha Washington Inn And Spa

150 West Main Street Abingdon VA

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9.4/10 Exceptional! (179 reviews)

5 star hotels in Southwestern Virginia

The Lodge at Primland, Auberge Collection

2000 Busted Rock Rd Meadows Of Dan VA

$1,744 nightly

$1,958 total

Oct 19 - Oct 20

Total with taxes and fees

9/10 Wonderful! (34 reviews)

Southwestern Virginia Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southwestern Virginia luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southwestern Virginia to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southwestern Virginia will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southwestern Virginia, and plan your next opulent escape.

Southwestern Virginia hotels essential information

Accommodation	1,913 hotels
Lowest Price	$63
Highest Price	$1,958
Popular hotels	Natural Bridge Hotel, Trademark Collection by Wyndham, SureStay Hotel by Best Western Christiansburg Blacksburg, Hotel Roanoke & Conference Ctr, Curio Collection by Hilton , Ramada by Wyndham Wytheville, Super 8 by Wyndham Radford VA, Motel 6 Bristol, VA, Motel 6 Hillsville, VA, Travel Lite Motel