Book Hotels in Southeast Illinois, IL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Jul 24 - Jul 25
Tomorrow
Jul 25 - Jul 26
This weekend
Jul 25 - Jul 27
Next weekend
Aug 1 - Aug 3

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Southeast Illinois hotels

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America, Effingham, IL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Jul 27 to Jul 28
$113 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Great
"Needs some minor updates, but a very pleasant stay, very clean and comfortable. Good breakfast."

Reviewed on Jul 22, 2025

La Quinta Inn & Suites by Wyndham Effingham
Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $114 total per night from Jul 27 to Jul 28
$114 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"very helpful staff"

Reviewed on Jul 20, 2025

Best Western Delta Inn
Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG

3.5 out of 5
1301 Avenue Of Mid America, Effingham, IL
Fully refundable
$105 nightly
The price is $118 total per night from Aug 3 to Aug 4
$118 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Superb service and assistance from the entire team during the threat of an imminent tornado! The staff was fabulous in checking in guests who were seeking shelter during the threat of a tornado as well as meeting their needs. They remained calm, collected, kind and caring throughout the evening! ..."

Reviewed on Jul 22, 2025

Holiday Inn Effingham by IHG
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

2.5 out of 5
1200 N Raney, Effingham, IL
Fully refundable
$104 nightly
The price is $115 total per night from Jul 27 to Jul 28
$115 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Needs renovation."

Reviewed on Jul 21, 2025

Country Inn & Suites by Radisson, Effingham, IL
Economy Inn & Suites

Economy Inn & Suites

2 out of 5
411 E Poplar St, Harrisburg, IL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Jul 27 to Jul 28
$83 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features free WiFi in public areas, concierge services, and free self parking. Enjoy the free continental breakfast each morning. A terrace and a ...
"It was all good except the hotel manager said he would possibly give me an adjustment on the price when I told him I could be a regular customer. Then when I"

Reviewed on Jul 21, 2025

Economy Inn & Suites
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street, Metropolis, IL
Fully refundable
$107 nightly
The price is $119 total per night from Aug 24 to Aug 25
$119 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Spacious and clean"

Reviewed on Jul 13, 2025

Holiday Inn Express Metropolis by IHG
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

2.5 out of 5
1811 W Fayette Avenue, I-57 & 70 Exit 159, Effingham, IL
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $82 total per night from Aug 10 to Aug 11
$82 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The staff was very courteous and helpfully, going above and beyond to make sure that our stay went well."

Reviewed on Jul 21, 2025

Baymont by Wyndham Effingham
Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey

2 out of 5
933 N Route 49, Casey, IL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Jul 27 to Jul 28
$83 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"Great location and a quite place to stay and relax"

Reviewed on Jul 13, 2025

Days Inn & Suites by Wyndham Casey
Suite Dreams Hotel

Suite Dreams Hotel

2.5 out of 5
300 Broadway Avenue East, Mattoon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Jul 25 to Jul 26
$105 total
Jul 25 - Jul 26
Total includes taxes and fees
This hotel features a restaurant and 2 bars/lounges. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Perfect location to walk to Bagelfest"

Reviewed on Jul 20, 2025

Suite Dreams Hotel
Don't see what you're looking for?
See all available properties in Southeast Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Illinois hotels

Days Inn by Wyndham Charleston

Days Inn by Wyndham Charleston

810 West Lincoln Avenue, Charleston, IL
$82 nightly
The price is $91 total per night from Jul 27 to Jul 28
$91 total
Jul 27 - Jul 28
Total includes taxes and fees
7.6/10 Good! (742 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Illinois hotel reviews by fellow wanderers

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Amazing! Great food, comfortable beds and very clean. "
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity