Book Hotels in Southeast Illinois, IL

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Top Southeast Illinois hotels

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jan 16 to Jan 17
$125 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Enjoyed my stay. Always good.

Reviewed on Jan 9, 2026

Opens in a new windowDrury Plaza Hotel Mt. Vernon
Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham

2.5 out of 5
1305 N Keller Dr Effingham IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Jan 18 to Jan 19
$117 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A snack ...
The room was immaculate and so very comfortable. The staff was courteous and helpful. If we have another opportunity, we will definitely stay there again.

Reviewed on Jan 6, 2026

Opens in a new windowHampton Inn & Suites Effingham
Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG

2.5 out of 5
1604 West Fayette Avenue Effingham IL
Fully refundable
$83 nightly
The price is $93 total per night from Feb 6 to Feb 7
$93 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Everything was great the gentleman that checked us in was awesome and the rooms are clean and a great size

Reviewed on Jan 7, 2026

Opens in a new windowHoliday Inn Express & Suites Effingham by IHG
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America Effingham IL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Feb 1 to Feb 2
$105 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
room was clean. staff was very nice and accommodating

Reviewed on Jan 4, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Effingham
Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr Effingham IL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Feb 3 to Feb 4
$94 total
Feb 3 - Feb 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Perfect

Reviewed on Jan 8, 2026

Opens in a new windowBest Western Delta Inn
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street Metropolis IL
Fully refundable
$106 nightly
The price is $118 total per night from Jan 25 to Jan 26
$118 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Clean hotel and room. Staff nice. The bed was comfortable and overall quiet. Very nice breakfast with hot and cold options.

Reviewed on Jan 3, 2026

Opens in a new windowHoliday Inn Express Metropolis by IHG
Unique Suites Hotel

Unique Suites Hotel

2.5 out of 5
920 W Lincoln Ave Charleston IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Jan 26 to Jan 27
$89 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
Room was very nice, a few light bulbs needed to be changed, but the room was clean and easy parking.

Reviewed on Dec 22, 2025

Opens in a new windowUnique Suites Hotel
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

3.5 out of 5
100 E Front St Metropolis IL
$117 nightly
The price is $130 total per night from Feb 9 to Feb 10
$130 total
Feb 9 - Feb 10
Total with taxes and fees
This hotel features a casino and 2 restaurants. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A snack bar/deli, ...
Very nice welcome to the hotel

Reviewed on Dec 29, 2025

Opens in a new windowHarrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

2.5 out of 5
1811 W Fayette Avenue Effingham IL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $78 total per night from Jan 17 to Jan 18
$78 total
Jan 17 - Jan 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room, staff friendliness and great breakfast choices.

Reviewed on Jan 6, 2026

Opens in a new windowBaymont by Wyndham Effingham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Illinois hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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