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Top Santa Isabel hotels

Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali

3 out of 5
Calzada Manuel Gomez Morin 856 Mexicali BC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from May 29 to May 30
$124 total
May 29 - May 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 6 ...
Extra friendly & helpfull staff. Very convenient parking garage.

Reviewed on May 4, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Mexicali
Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Boulevard Benito Juarez 2151 Mexicali BC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from May 6 to May 7
$120 total
May 6 - May 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
My husband and I like staying at Lucerna because it's got a perfect location. Thank you

Reviewed on May 5, 2026

Opens in a new windowHotel Lucerna Mexicali
Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
Blvd. Benito Juarez 2220 Mexicali BC
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $137 total per night from May 11 to May 12
$137 total
May 11 - May 12
Total with taxes and fees
This smoke-free hotel features 2 outdoor pools, a hot tub, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. ...
It was an 8 out of ten. Ten being best.

Reviewed on May 4, 2026

Opens in a new windowHotel Araiza Mexicali
City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali

3.5 out of 5
Avenida Republica de Cuba 39 Mexicali BC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $104 total per night from May 10 to May 11
$104 total
May 10 - May 11
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
Parking was not great, pool was empty and was a huge disappointment. Breakfast was fresh and room and facilities were clean..

Reviewed on May 4, 2026

Opens in a new windowCity Express Plus by Marriott Mexicali
Fiesta Inn Mexicali

Fiesta Inn Mexicali

3.5 out of 5
Calz Adolfo Lopez Mateos 1029 Mexicali BC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from May 31 to Jun 1
$103 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Worst service

Reviewed on Apr 26, 2026

Opens in a new windowFiesta Inn Mexicali
Real Inn Mexicali

Real Inn Mexicali

4 out of 5
Avenida de Los Heroes 201 Mexicali BC
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $84 total per night from May 13 to May 14
$84 total
May 13 - May 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
When we got our room, first thing that we saw it was water on the floor, checked the bathroom and trash can was full, sink was water all over, they gave us a dirty room ☹️ I Went downstairs to get another room. I don’t know if I will stay there again . They need to pay attention of what are the employees ...

Reviewed on May 5, 2026

Opens in a new windowReal Inn Mexicali
Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña

3 out of 5
Calzada Manuel Gomez Morin, 886 Mexicali BC
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $56 total per night from Jun 4 to Jun 5
$56 total
Jun 4 - Jun 5
Total with taxes and fees
This aparthotel features an outdoor pool and a 24-hour gym. WiFi in public areas is free. Self parking is offered and multilingual staff can provide around-the-clock ...
Elevator was not working.

Reviewed on May 4, 2026

Opens in a new windowExtended Suites Mexicali Cataviña
Hotel Colonial Mexicali

Hotel Colonial Mexicali

3.5 out of 5
Blvd Lopez Mateos 1048 Mexicali BC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from May 6 to May 7
$92 total
May 6 - May 7
Total with taxes and fees
This hotel features 2 outdoor pools and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice and quiet

Reviewed on May 5, 2026

Opens in a new windowHotel Colonial Mexicali
One Mexicali

One Mexicali

3 out of 5
Avenida Republica de Cuba 22 Mexicali BC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from May 9 to May 10
$81 total
May 9 - May 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
.

Reviewed on May 4, 2026

Opens in a new windowOne Mexicali
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Isabel?
Take some of the troubles out of traveling with kids by opting for a family-friendly hotel in Santa Isabel. From thoughtful amenities to extra-helpful services, these stays offer perks that'll help make your trip go off without a hitch: OYO Hotel Don Juan will help make your vacation the most memorable one yet. It features plenty of nice little touches, such as housekeeping services and free WiFi. Alternatively, spend your nights in Santa Isabel at Méxicali Home in Private Gated Community. Make the most of a travel crib, pet-friendly facilities and more here.
Where can I find cheap hotels in Santa Isabel?
At Travelocity you'll find really nice hotels in Santa Isabel at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Isabel rather than in Santa Isabel. We may find you even better rates, too.
How do I find the best Santa Isabel hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Isabel then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Isabel?
The cheapest hotel in Santa Isabel is $56. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Isabel?
There are 72 hotels in Santa Isabel on Travelocity.
What are the best hotels in Santa Isabel?
Santa Isabel has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Isabel for you!
When is the best time to visit Santa Isabel?
If you want the joy of a fun-filled trip in peak season, visit Santa Isabel during March, April and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, June and December.
When is the cheapest time to stay in Santa Isabel?
Based on historic data is usually the cheapest month to visit Santa Isabel. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Isabel?
There are multiple hotels in Santa Isabel that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Isabel. We have plenty of kid-friendly hotels in Santa Isabel to choose from on Travelocity!
Why book a hotel in Santa Isabel through Travelocity?
Because we have the top hotels in Santa Isabel! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Isabel on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Isabel hotel reviews by fellow wanderers

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"My husband and I like staying at Lucerna because it's got a perfect location. Thank you"
A verified traveler stayed at Hotel Lucerna Mexicali
Hotel Lucerna Mexicali

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