Book Hotels in Santa Cruz

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Cruz hotels

Moa Select

Moa Select

3 out of 5
Cra 81 # 30A-122 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $62 total per night from Nov 14 to Nov 15
$62 total
Nov 14 - Nov 15
This hotel doesn't skimp on freebies - guests receive free cooked-to-order breakfast and free WiFi. If you want to take your pet along, this pet-friendly property ...
"ABSOLUTAMENTE TODO excelente. Servicio. Limpieza. Habitacion. Decoración. Desayunos. 100% recomendados"

Reviewed on Oct 25, 2026

Opens in a new windowMoa Select
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $70 total per night from Nov 16 to Nov 17
$70 total
Nov 16 - Nov 17
This hotel features an outdoor pool and a gym. Relax with a drink at the poolside bar and enjoy perks like free WiFi. A garden is provided and the front desk ...
"The property speaks for its self"

Reviewed on Oct 26, 2026

Opens in a new windowHeiss Hotel By Jalo
Urbit Social Lofts

Urbit Social Lofts

3 out of 5
757 Tv. 39B Medellín Antioquia
Fully refundableReserve now, pay when you stay
$44 nightly
The price is $44 total per night from Oct 28 to Oct 29
$44 total
Oct 28 - Oct 29
Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. Enjoy the free buffet breakfast each morning. Multilingual staff ...
"Poor guest and customer service. When we arrived there was no space for the car to stop so we could unload our bags. It was not a good experience as a man from the street is the one in charge of the street and doesn’t allow cars from guests to stop at the hotel so we can unload our bag as. No management ..."

Reviewed on Oct 27, 2026

Opens in a new windowUrbit Social Lofts
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $73 total per night from Nov 10 to Nov 11
$73 total
Nov 10 - Nov 11
This smoke-free hotel features 2 restaurants, a bar/lounge, and an outdoor pool. WiFi in public areas is free. Dry cleaning and luggage storage are also ...
"This is a party hotel for people looking to drink, party, and partake in the oldest profession. Walls are paper thin, bumping bass all night. Carpet was not vacuumed, and visibly dirty, tv did not work, and was told breakfast was not included, even though my reservation clearly said it was. Look, ..."

Reviewed on Oct 26, 2026

Opens in a new windowCalle Flora Hotel by Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $75 total per night from Oct 28 to Oct 29
$75 total
Oct 28 - Oct 29
This traditional hotel features a casino, a nightclub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
"Great view of the city and very close to event"

Reviewed on Oct 27, 2026

Opens in a new windowHotel Dorado La 70
Blues Suites Medellin

Blues Suites Medellin

4 out of 5
Cra 29C #1a sur 80 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $87 total per night from Oct 28 to Oct 29
$87 total
Oct 28 - Oct 29
This hotel features 2 restaurants and a rooftop terrace. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. Relax with ...
"Great place, location, and warm, helpful staff!"

Reviewed on Oct 26, 2026

Opens in a new windowBlues Suites Medellin
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

4.5 out of 5
Carrera 43a No.7-50, Avenida El Poblado Medellín Antioquia
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $94 total per night from Nov 22 to Nov 23
$94 total
Nov 22 - Nov 23
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
"This is my go to hotel every time I go to Medellin. The breakfast is wonderful"

Reviewed on Oct 25, 2026

Opens in a new windowDann Carlton Medellin Hotel
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

4 out of 5
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $70 total per night from Nov 2 to Nov 3
$70 total
Nov 2 - Nov 3
This hotel features a restaurant, free WiFi in public areas, and a safe deposit box. The front desk is staffed around-the-clock and concierge services are on ...
Opens in a new windowHashtag 98 Hotel By Jalo
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

5 out of 5
Calle 10B # 37-29 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $193 total per night from Nov 16 to Nov 17
$193 total
Nov 16 - Nov 17
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
Opens in a new windowThe Click Clack Hotel Medellin
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz?
Family getaways are where you make the best memories, but it's no secret that traveling with little ones can be demanding. These kid-friendly Santa Cruz hotels come with perks that aim to keep young and old alike comfortable and happy: Settle in at Casa Grande Medellin Comuna 1. It comes with a king bed, pet-friendly facilities and a talent for making families feel welcome. Apartment is another great choice. After a big day of exploring, come home to your comfy room and amenities like pet-friendly facilities and internet access.
Where can I find cheap hotels in Santa Cruz?
At Travelocity you'll find really nice hotels in Santa Cruz at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz rather than in Santa Cruz. We may find you even better rates, too.
How do I find the best Santa Cruz hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz?
The cheapest hotel in Santa Cruz is $44. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz?
There are 4,653 hotels in Santa Cruz on Travelocity.
What are the best hotels in Santa Cruz?
Santa Cruz has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz for you!
When is the best time to visit Santa Cruz?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz during March, May and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, November and December.
When is the cheapest time to stay in Santa Cruz?
Based on historic data is usually the cheapest month to visit Santa Cruz. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz?
There are multiple hotels in Santa Cruz that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz. We have plenty of kid-friendly hotels in Santa Cruz to choose from on Travelocity!
Why book a hotel in Santa Cruz through Travelocity?
Because we have the top hotels in Santa Cruz! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz hotel reviews by fellow wanderers

Hotel Dorado La 70

Hotel Dorado La 70

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Great view of the city and very close to event"
A verified traveler stayed at Hotel Dorado La 70
Hotel Dorado La 70

Explore More Ways to Travel with Travelocity