Book Hotels in Santa Clara

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Clara hotels

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
$104 nightly
The price is $104 total per night from Oct 4 to Oct 5
$104 total
Oct 4 - Oct 5
Total with taxes and fees
This bed & breakfast features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. An area shuttle, ...
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."

Reviewed on Jun 17, 2026

Opens in a new windowVilla Botero By Casa Mojito B&B
The Golden Frog Inn

The Golden Frog Inn

3 out of 5
Calle Las Veraneras El Valle de Anton Panama
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Sep 29 to Sep 30
$103 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free ...
"On a walk on a side road just outside of town my wife tripped and fell face first into the pavement. She sprained her ankle and badly bruised her entire face and her nose was broken in a few places. A stranger gave us a lift back to the hotel. My wife limped into the lobby, Her face wa bleeding and ..."

Reviewed on Sep 25, 2026

Opens in a new windowThe Golden Frog Inn
Casa Caracol Boutique Hotel

Casa Caracol Boutique Hotel

2 out of 5
C. Corona 21, Playa Corona Las Uvas Panamá Oeste
$57 nightly
The price is $64 total per night from Oct 5 to Oct 6
$64 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning, luggage storage, and concierge services are also on ...
"We were terribly disappointed with communications with the property. The internet site says that a door code is sent 24 hours before checkin but on the morning of our arrival we still had not received a code. We tried for 3 hours whatsapp and calling direct but no repsonse. As we were looking at ..."

Reviewed on Sep 25, 2026

Opens in a new windowCasa Caracol Boutique Hotel
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

3.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
$177 nightly
The price is $194 total per night from Oct 21 to Oct 22
$194 total
Oct 21 - Oct 22
Total with taxes and fees
This all-inclusive hotel features a private beach, a nightclub, and 4 restaurants. Bring the family and enjoy the free kid's club, children's pool, and waterslide. ...
"Todo bien solo que un bar no tenian cervezas"

Reviewed on Sep 26, 2026

Opens in a new windowGran Evenia Bijao - All Inclusive
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
A poolside bar is on site and the staff is available around-the-clock at the 24-hour front desk. There's fun for all ages with a children's club and a children's ...
"Todo muy bien.hay que hacer adecuaciones en las areas de Piscina estan antiguas."

Reviewed on Sep 26, 2026

Opens in a new windowHotel Riu Playa Blanca - All Inclusive
Playa Blanca Beach Resort - All Inclusive

Playa Blanca Beach Resort - All Inclusive

4 out of 5
115 Km Via Interamericana Rio Hato Cocle
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $173 total per night from Sep 30 to Oct 1
$173 total
Sep 30 - Oct 1
Total with taxes and fees
This smoke-free property features a private beach, free water park access, and a casino. Spend a day at the beach kayaking, or relax with sun loungers and beach ...
"Muy buena atención al cliente, en especial en recepción del town center, muy buen trato en todo, la comida muy buena y en general todo bien."

Reviewed on Sep 21, 2026

Opens in a new windowPlaya Blanca Beach Resort - All Inclusive
Grand Decameron Panama, A Trademark  Resort

Grand Decameron Panama, A Trademark Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $167 total per night from Sep 28 to Sep 29
$167 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa is on site and multilingual staff is available around-the-clock at the 24-hour front desk. Enjoy beachfront dining and relax with free beach ...
Opens in a new windowGrand Decameron Panama, A Trademark Resort
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5 out of 5
340 Calle 3ra Buenaventura El Chiru Cocle
$199 nightly
The price is $219 total per night from Oct 18 to Oct 19
$219 total
Oct 18 - Oct 19
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Opens in a new windowThe Buenaventura Golf & Beach Resort Panama, Autograph Collection
Hotel La Compania Del Valle

Hotel La Compania Del Valle

5 out of 5
C. El Ciclo El Valle de Anton
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $214 total per night from Sep 28 to Sep 29
$214 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor tennis court are all featured at this luxury hotel. Enjoy the gym and perks like free self parking and free ...
Opens in a new windowHotel La Compania Del Valle
Don't see what you're looking for?
See all available properties in Santa Clara
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Clara Hotel & Travel Guide\n

60 miles (94 kilometers) to the southwest of 60 miles (94 kilometers)'s center is the neighborhood of Santa Clara.

The Bridge of the Americas, Miraflores Locks and Gatun Locks are some of the excellent tourist attractions you are able to visit in Panama.

Santa Clara is found in Panama. There you have the choice of staying at the Casa Guardia Panama and Royal Decameron Golf, Beach Resort and Villas All Inclusive, which are all a few blocks away from the Santa Clara Beach.

Tocumen, around 70 miles (111 kilometers) from Santa Clara, features a selection of hotels and other accommodations.

They say traveling teaches the best lessons so visit Travelocity's database and book a Santa Clara accommodation option.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
From cool amenities to more room to move, kid-friendly hotels come with features that can help turn a good family vacation into a sensational one. These Santa Clara properties make traveling with young ones a breeze: Villa Botero By Casa Mojito B&B will help make your next trip the most memorable one yet. It features a range of conveniences geared toward families, such as a swimming pool and a nearby beach. Otherwise, spend your Santa Clara trip at Las Sirenas de Santa Clara. Take advantage of a nearby beach, pet-friendly facilities and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $64. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 506 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers