Explore beach hotels in Otay Mesa, CA from $128
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Top Otay Mesa Beach Resorts & Hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
Fully refundable
$127 nightly
The price is $144 total per night from Jul 10 to Jul 11
$144 total
Jul 10 - Jul 11
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
7.6/10 Good! (1,397 reviews)
"Team are very professional and very polite"
Reviewed on Jun 30, 2025

Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $128 total per night from Jul 29 to Jul 30
$128 total
Jul 29 - Jul 30
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the ...
7/10 Good! (1,001 reviews)
Not bad ! I will stay there again! Next time
"I wish had more real food for breakfast they had only hard boil eggs"
Reviewed on Jul 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beach Condos in Otay Mesa

South Mission Beach Oceanfront condo on the sand
San Diego
9.4/10 Exceptional! (80 reviews)
Beach Villas in Otay Mesa

Hidden Villa- A Hidden Paradise with beautiful furnished garden patio
San Diego
10/10 Exceptional! (121 reviews)
Popular Beach Stays in Otay Mesa
Recent Otay Mesa Hotel Reviews By Fellow Wanderers

The Dana on Mission Bay
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Love this hotel. Lanai rooms are especially awesome. Stay here every year."
A verified traveler stayed at The Dana on Mission Bay
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