Explore beach hotels in Otay Mesa, CA from $124

Name: Quality Suites San Diego Otay Mesa
Price range: $124 total
Rating: 7

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Top Otay Mesa Beach Resorts & Hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2296 Niels Bohr Ct San Diego CA

Fully refundable

$119 nightly

$135 total

Dec 21 - Dec 22

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

8/10 Very Good! (1,562 reviews)

Great place to stay. Really clean and helpful staff

Reviewed on Dec 12, 2025

Quality Suites San Diego Otay Mesa

2351 Otay Center Dr San Diego CA

Fully refundableReserve now, pay when you stay

$109 nightly

$124 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

This hotel features a gym and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...

7/10 Good! (1,001 reviews)

This is not the best hotel but it definitely serves the purpose. You can hear noise and the room had a little bit of a smell. It was clean and we had no problems at all

Reviewed on Dec 6, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.