
Exclusive Mississippi River Vacation Deals
Mississippi River vacation package deals
Price found within the past 48 hours. Click for updated prices.

Old 77 Hotel
New Orleans Central Business District
Save 100% on your flight
Price was $693, price is now $431 per person
$431
per person
Oct 26 - Nov 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to New Orleans (MSY)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Self parking, a coffee shop, and a snack bar/deli are also offered.

Hampton Inn & Suites Chicago Medical District UIC
Near West Side
Save 100% on your flight
Price was $820, price is now $433 per person
$433
per person
Oct 22 - Oct 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free full breakfast each morning.

The Emily Hotel
Downtown Chicago
Price was $1,288, price is now $720 per person
$720
per person
Nov 21 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a snack bar/deli, and luggage storage are also on offer.

The Revelry
Central City
Save 100% on your flight
Price was $2,462, price is now $1,432 per person
$1,432
per person
Nov 6 - Nov 9
found 16 hours ago
Roundtrip flight included
Atlanta (ATL) to New Orleans (MSY)
An outdoor pool is featured at this aparthotel, along with free WiFi in public areas and a garden. A picnic area and barbecue grills are also provided.

Hyatt Regency New Orleans
New Orleans Central Business District
Save 100% on your flight
Price was $736, price is now $439 per person
$439
per person
Nov 22 - Nov 26
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to New Orleans (MSY)
This smoke-free hotel features 3 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and a 24-hour front desk and a coffee shop are also provided.

The Langham, Chicago
Downtown Chicago
Price was $2,072, price is now $1,288 per person
$1,288
per person
Oct 31 - Nov 5
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Chicago (ORD)
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the gym, bar/lounge, and laundry facilities.
Frequently asked questions
Top Mississippi River hotel deals

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
$123 nightly
The price is $143 total per night
$143 total
Sep 14 - Sep 15
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Parking included
Restaurant

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $122 total per night
$122 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $147 total per night
$147 total
Oct 2 - Oct 3
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.
Pet friendly
Free WiFi
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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