
Exclusive Mississippi River Vacation Deals

Mississippi River vacation package deals
Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Chicago
Downtown Chicago
Save 100% on your flight
Price was $735, price is now $352 per person
$352
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features 2 bars/lounges and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy a meal from the restaurant and free buffet breakfast each morning.

Hilton Grand Vacations Club Chicago Magnificent Mile
Downtown Chicago
Price was $785, price is now $359 per person
$359
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features a restaurant, a gym, and a poolside bar. Enjoy the seasonal outdoor pool and perks like free WiFi. Self parking, a 24-hour business center, and a coffee shop are also offered.

Pendry Chicago
Downtown Chicago
Price was $1,020, price is now $483 per person
$483
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the a rooftop terrace and perks like free WiFi. Valet parking, a coffee shop, and a terrace are also offered.

theWit Chicago, a Hilton Hotel
Downtown Chicago
Save 100% on your flight
Price was $726, price is now $375 per person
$375
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, express check-in, and valet parking. Limo/town car service, WiFi in public areas, and express check-out are also on offer.

The Emily Hotel
Downtown Chicago
Price was $1,003, price is now $523 per person
$523
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. A coffee shop, a snack bar/deli, and luggage storage are also on offer.

The Blackstone, Autograph Collection
Downtown Chicago
Save 100% on your flight
Price was $710, price is now $373 per person
$373
per person
Jan 16 - Jan 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Chicago (ORD)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self parking, a lobby fireplace, and express check-in are also offered.
Frequently asked questions
Top Mississippi River hotel deals

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $138 total per night
$138 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.
Pool
Free airport shuttle

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $117 total per night
$117 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pool
Breakfast included

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
$144 nightly
The price is $168 total per night
$168 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore More Ways to Travel with Travelocity
- Farmstay in Central United States
- Chalets in Central United States
- Condo Resorts in Central United States
- Condos in Central United States
- Guest Houses in Central United States
- Adults Only Resorts & in Central United States
- All Inclusive Resorts & in Central United States
- Beach Resorts & in Central United States
- Benchmark Hotels in Central United States
- Citizenm Hotels in Central United States
- Drury Inn & Suites Hotels in Central United States
- Four Seasons Hotels in Central United States
- Hilton Hotels in Central United States
- Hotels with Early Check-in in Central United States
- Hotels with Waterslides in Central United States
- Hyatt Hotels in Central United States
- Loews Hotels in Central United States
- Pet Friendly Hotels in Central United States
- Remington Hotels in Central United States
- Ski Resorts and in Central United States
- Sonesta Hotel in Central United States
- Spa Resorts & in Central United States
- Waterpark Hotels and Resorts in Central United States
- Wyndham Hotels in Central United States
- Central United States Hotels
- Vacation Homes in Central United States
- Rv Parks in Central United States
- Apartments in Southeast Iowa
- B&B in Southeast Iowa
- Cabins in Southeast Iowa
- Condos in Southeast Iowa
- Cottages in Southeast Iowa
- Casino Resorts & in Southeast Iowa
- Kid Friendly Hotels in Southeast Iowa
- Hotels with Pools in Southeast Iowa
- Hotels with Bar in Southeast Iowa
- Hotels with Hot Tubs in Southeast Iowa
- Hotels with Waterslides in Southeast Iowa
- Luxury Hotels in Southeast Iowa
- Pet Friendly Hotels in Southeast Iowa
- Romantic Getaways & Hotels in Southeast Iowa
- Waterpark Hotels and Resorts in Southeast Iowa
- Southeast Iowa Hotels
- Lodges in Southeast Iowa
- Motels in Southeast Iowa
- Vacation Homes in Southeast Iowa
- 5 Star Hotels in Quad Cities
- Apartments in Quad Cities
- B&B in Quad Cities
- Cabins in Quad Cities
- Cottages in Quad Cities
- Extended Stay Hotels in Quad Cities
- Casino Resorts & in Quad Cities
- Cheap Hotels in Quad Cities
- Kid Friendly Hotels in Quad Cities
- Golf Resorts & in Quad Cities
- Hotels with Early Check-in in Quad Cities
- Hotels with Bar in Quad Cities
- Hotels with Hot Tubs in Quad Cities
- Hotels with an Indoor Pool in Quad Cities
- Pet Friendly Hotels in Quad Cities
- Romantic Getaways & Hotels in Quad Cities
- Spa Resorts & in Quad Cities
- Waterpark Hotels and Resorts in Quad Cities
- Quad Cities Hotels
- Houseboats in Quad Cities
- Motels in Quad Cities
- Vacation Homes in Quad Cities
- Rv Parks in Quad Cities
- Flights to Central United States
- Flights from Miami to Central United States
- Flights from Atlanta to Southeast Iowa
- Flights from Chicago to Southeast Iowa
- Flights from Portland to Southeast Iowa
- Flights from Omaha to Southeast Iowa
- Flights from Tulsa to Southeast Iowa
- Flights to Quad Cities
- Flights from Brussels to Quad Cities
- Flights from Calgary to Quad Cities
- Flights from Indianapolis to Quad Cities
- Flights from Minneapolis - St. Paul to Quad Cities
- Flights from Nashville to Quad Cities
- Flights from Atlantic City to Quad Cities
- Flights from Lincoln to Quad Cities
- Flights from Boise to Quad Cities
- Car rentals near Central United States
- Car rentals near Southeast Iowa
- Minivan Car Rentals in Southeast Iowa
- Pickup Car Rentals in Southeast Iowa
- Car rentals near Quad Cities
- Convertible Car Rentals in Quad Cities
- Luxury Car Rentals in Quad Cities
- Pickup Car Rentals in Quad Cities
- Suv Car Rentals in Quad Cities