There is nothing more refreshing than a day at the spa. And the pure relaxation of spa hotels in Mesquite is the epitome of rejuvenation. Pamper yourself while in Mesquite with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Mesquite offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Mesquite spa hotels, and prepare to relax.