Explore 4 Luxury Hotels in Greenville Downtown

Name: Holiday Inn Express & Suites Greenville - Downtown by IHG
Price range: $125 total
Rating: 8.6

Best Luxury Hotels in Greenville Downtown

The Westin Poinsett Greenville

120 South Main St, Greenville, SC

Fully refundableReserve now, pay when you stay

$184 nightly

$203 total

Jun 29 - Jun 30

Total includes taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...

9.2/10 Wonderful! (1,001 reviews)

"Very nice"

Reviewed on May 29, 2025

Hampton Inn & Suites Greenville-Downtown-RiverPlace

171 Riverplace, Greenville, SC

Fully refundableReserve now, pay when you stay

$147 nightly

$163 total

Jun 29 - Jun 30

Total includes taxes and fees

This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (1,002 reviews)

"The staff went above and beyond to make our anniversary weekend special! We will be back!"

Reviewed on May 29, 2025

Hyatt Regency Greenville

220 N Main St, Greenville, SC

Fully refundableReserve now, pay when you stay

$131 nightly

$144 total

Jun 30 - Jul 1

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (1,006 reviews)

"Was a wonderful stay. Staff was so friendly and such a perfect location. We'll be back for sure!"

Reviewed on May 31, 2025

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Holiday Inn Express & Suites Greenville - Downtown by IHG

407 North Main Street, Greenville, SC

Fully refundable

$114 nightly

$125 total

Jun 29 - Jun 30

Total includes taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

8.6/10 Excellent! (1,005 reviews)

"Overall it was nice. Only complaint was about the bathroom: no exhaust and the water pressure wasn't great."

Reviewed on Jun 2, 2025

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Greenville Downtown

Southern Sunshine Retreat

901 Huntington Rd, Easley, Sc 29642, Usa, Easley, SC

Get rates

Greenville Downtown Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Greenville Downtown luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Greenville Downtown to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Greenville Downtown will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Greenville Downtown, and plan your next opulent escape.

Greenville Downtown hotels essential information

Accommodation	1,040 hotels
Lowest Price	$125
Highest Price	$203
Popular hotels	The Westin Poinsett Greenville, Hyatt Regency Greenville, Hampton Inn & Suites Greenville-Downtown-RiverPlace, Holiday Inn Express & Suites Greenville - Downtown by IHG

Popular Luxury Stays in Greenville Downtown

5 Stars Luxury stays in Greenville Downtown

Luxury stays in Greenville Downtown with spa

Popular places to visit

Falls Park on the Reedy

4.5/5(583 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.