Book Hotels in Commerce, MO

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Top Commerce hotels

The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Oct 28 to Oct 29
$112 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
"We were passing through and pleasantly surprised! Clean, well appointed, super friendly staff - everyone seemed happy t work there, and all around great. A real Starbucks in the lobby plus extra security because of the casino in the parking lot were huge plusses. 😊"

Reviewed on Oct 5, 2026

Opens in a new windowThe Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Oct 11 to Oct 12
$105 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"No exhaust fan in the bathroom. Other than that very clean comfortable hotel"

Reviewed on Oct 5, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
Fully refundable
$101 nightly
The price is $115 total per night from Oct 11 to Oct 12
$115 total
Oct 11 - Oct 12
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"Perfect location, beds were awesome & staff were friendly & accommodating!"

Reviewed on Oct 5, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
Fully refundable
$85 nightly
The price is $101 total per night from Oct 11 to Oct 12
$101 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, ..."

Reviewed on Oct 3, 2026

Opens in a new windowCandlewood Suites Cape Girardeau by IHG
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Oct 11 to Oct 12
$113 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Oct 11 to Oct 12
$108 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Oct 11 to Oct 12
$81 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Opens in a new windowPear Tree Inn Cape Girardeau West
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $87 total per night from Nov 1 to Nov 2
$87 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Oct 11 to Oct 12
$114 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Opens in a new windowFairfield Inn & Suites by Marriott Cape Girardeau
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See all available properties in Commerce
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Commerce?
Family vacations are where you make the best memories, but traveling with young ones can be stressful. These kid-friendly Commerce hotels offer perks that aim to keep visitors of all ages comfortable and happy: Your gang will enjoy staying at Serenity South -- Gardens, River-Views, and Refreshing Space. A water park and animal viewing activities are among the things that help make this property an appealing option. Otherwise, spend your evenings in Commerce at Newly re-listed downtown historic apartment. Make the most of a fireplace, internet access and more here.
Where can I find cheap hotels in Commerce?
At Travelocity you'll find really nice hotels in Commerce at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Commerce rather than in Commerce. We may find you even better rates, too.
How do I find the best Commerce hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Commerce then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Commerce?
The cheapest hotel in Commerce is $81. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Commerce?
There are 88 hotels in Commerce on Travelocity.
What are the best hotels in Commerce?
Commerce has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Commerce for you!
When is the best time to visit Commerce?
If you want the joy of a fun-filled trip in peak season, visit Commerce during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, October and December.
When is the cheapest time to stay in Commerce?
Based on historic data is usually the cheapest month to visit Commerce. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Commerce?
There are multiple hotels in Commerce that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Commerce. We have plenty of kid-friendly hotels in Commerce to choose from on Travelocity!
Why book a hotel in Commerce through Travelocity?
Because we have the top hotels in Commerce! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Commerce on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Commerce hotel reviews by fellow wanderers

The Riverview

The Riverview

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"We were passing through and pleasantly surprised! Clean, well appointed, super friendly staff - everyone seemed happy t work there, and all around great. A real Starbucks in the lobby plus extra security because of the casino in the parking lot were huge plusses. 😊"
A verified traveler stayed at The Riverview
The Riverview

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