Book Hotels in Center, MO
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Top Center hotels

Sleep Inn & Suites
105 Lakeside Dr, Hannibal, MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $117 total per night from Nov 23 to Nov 24
$117 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
The breakfast menu was fresh and plenty of options.
Reviewed on Oct 19, 2025

WELCOME TO WESTHOFF CAMPGROUND BUNKHOUSE
Center
This cabin features a water park, a garden, and barbecue grills.
Once again we had a great time at your bunkhouse! Just a great location and everything you need for a nice family weekend! We will definitely be back again! Thank you for sharing your place with us!
Reviewed on Aug 10, 2025

Best Western On The River
401 North 3rd Street, Hannibal, MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Nov 2 to Nov 3
$126 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal ...
The room was very comfortable.
Reviewed on Oct 21, 2025

Quality Inn & Suites Hannibal
120 Lindsey Drive, Hannibal, MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $100 total per night from Nov 2 to Nov 3
$100 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
It was clean and comfortable
Reviewed on Oct 20, 2025

Comfort Inn & Suites - Hannibal
4000 Market St, Hannibal, MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Nov 2 to Nov 3
$102 total
Nov 2 - Nov 3
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Clean room, comfortable bed
Reviewed on Oct 22, 2025

Motel 6 Hannibal, MO
123 Huckleberry Heights Dr, Hannibal, MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $63 total per night from Nov 1 to Nov 2
$63 total
Nov 1 - Nov 2
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this motel's amenities. WiFi in public areas is free. A snack bar/deli and a fireplace in ...
It was a great place to stay the night while traveling. I really like the hard floor upgrade.
Reviewed on Oct 11, 2025

Days Inn by Wyndham Hannibal
4070 Market St, Hannibal, MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $74 total per night from Nov 13 to Nov 14
$74 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. A garden, express ...
Staff was great.
Reviewed on Sep 16, 2025

Baymont by Wyndham Hannibal
4141 Market St, Hannibal, MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $73 total per night from Oct 26 to Oct 27
$73 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
The room was clean and very spacious bathroom. Fridge, microwave and good lighting. Furniture was dated and bathroom tub & sink need plugs. Good shower and plenty of hot water. Pool was excellent! Need more towels & warm blankets in room for families.
Reviewed on Oct 19, 2025

MTL HUNTING LAYAWAY & OUTDOOR HANGOUT
Center, MO
$200 nightly
The price is $211 total per night from Oct 26 to Oct 27
$211 total
Oct 26 - Oct 27
Total with taxes and fees
A water park and an outdoor pool are featured at this smoke-free apartment. Families will appreciate the playground and barbecue grills.
Very nice and clean! So cozy and was perfect for our weekend at the lake!
Reviewed on Aug 31, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Center hotel reviews by fellow wanderers

Comfort Inn & Suites - Hannibal
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Clean room, comfortable bed"
A verified traveler stayed at Comfort Inn & Suites - Hannibal
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