Explore top 2026 5 Star Hotels in Andean Natural Region
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Top Andean Natural Region 5 Star hotels
The Click Clack Hotel Medellin
Calle 10B # 37-29 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$196 nightly
The price is $196 total per night from Oct 22 to Oct 23
$196 total
Oct 22 - Oct 23
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
The Charlee Hotel
Calle 9a 37 16 Medellín
$168 nightly
The price is $168 total per night from Oct 20 to Oct 21
$168 total
Oct 20 - Oct 21
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free ...
Medellin Marriott Hotel
Calle 1a Sur #43a-83 Medellín
Fully refundableReserve now, pay when you stay
$314 nightly
The price is $314 total per night from Oct 16 to Oct 17
$314 total
Oct 16 - Oct 17
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (647 reviews)
"It was a really nice convenient hotel"
Reviewed on Sep 25, 2026
NH Collection Medellín Royal
Carrera 42 No 5 Sur 130 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $121 total per night from Oct 25 to Oct 26
$121 total
Oct 25 - Oct 26
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Binn Hotel
Carrera 25 No. 10-51 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$181 nightly
The price is $181 total per night from Nov 3 to Nov 4
$181 total
Nov 3 - Nov 4
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
York Medellin, Curio Collection by Hilton
Carrera 43a 17sur 63 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $203 total per night from Oct 5 to Oct 6
$203 total
Oct 5 - Oct 6
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,138 reviews)
"The staff was amazing, the view was amazing, the breakfast was amazing, I would love to go back"
Reviewed on Oct 3, 2026
Wake BioHotel, a Member of Design Hotels
25115 Calle 2 Sur Medellín Antioquia
Fully refundableReserve now, pay when you stay
$236 nightly
The price is $236 total per night from Oct 8 to Oct 9
$236 total
Oct 8 - Oct 9
This hotel features 2 coffee shops/cafes and an outdoor pool. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking. You'll find a ...
Devú
# 9-32 Carrera 32d Medellín Antioquia
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $158 total per night from Oct 18 to Oct 19
$158 total
Oct 18 - Oct 19
This aparthotel features free WiFi in public areas, dry cleaning, and laundry facilities. Multilingual staff can provide around-the-clock assistance and concierge ...
9.8/10 Exceptional! (40 reviews)
"Wonderful place, very comfortable, great customer service just don’t get the airport transportation offered as it is more expensive than getting a regular Uber. Location is great and overall fantastic"
Reviewed on Sep 27, 2026
Bosko
46,5 km From José María Córdoba Airport Guatapé Antioquia
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $211 total per night from Oct 5 to Oct 6
$211 total
Oct 5 - Oct 6
Ski-in/ski-out access, a full-service spa, and 2 outdoor pools are all featured at this smoke-free lodge. Traveling on business? Take advantage of the free WiFi ...
9.6/10 Exceptional! (215 reviews)
"Es un lugar mágico"
Reviewed on Aug 15, 2026
Wake Medellin, a Member of Design Hotels
Calle 10b #35-27 El Poblado Medellín Antioquia
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $191 total per night from Oct 5 to Oct 6
$191 total
Oct 5 - Oct 6
A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. Luggage storage is also provided.
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Andean Natural Region Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Andean Natural Region to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Andean Natural Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Andean Natural Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Andean Natural Region hotel reviews by fellow wanderers
Hashtag 98 Hotel By Jalo
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"¡Nuestra primera vez visitando Medellín y no podríamos haber elegido un mejor lugar para hospedarnos! ❤️ Nos hospedamos en Hashtag 98 durante 5 noches y desde el momento en que llegamos nos sentimos muy bien recibidos. Valeria, de la recepción, fue maravillosa. Nos recibía con una sonrisa todos los días, sin importar la hora a la que entráramos al hotel. Siempre fue muy amable, servicial y estuvo dispuesta a ayudarnos con cualquier pregunta que tuviéramos. También queremos destacar a Hernán, el encargado de la puerta y seguridad del turno de la noche. Siempre fue un placer verlo cada noche cuando regresábamos después de pasar el día explorando la ciudad. Siempre nos recibía con una sonrisa y una actitud muy amable, lo que nos hacía sentir muy bienvenidos cada vez que regresábamos al hotel. El hotel está ubicado en un lugar ideal, a poca distancia caminando de muchísimas tiendas, restaurantes y de todo lo que queríamos conocer. Todo el personal fue muy amable, atento y siempre dispuesto a ayudarnos, lo que hizo que nuestra estadía fuera aún más agradable. Realmente nos encantó nuestra experiencia en Hashtag 98 y ya estamos pensando en regresar a Medellín… ¡y por supuesto volver a hospedarnos aquí! ¡Lo recomendamos muchísimo! 🇨🇴❤️ Carlos & Ginger"
A verified traveler stayed at Hashtag 98 Hotel By Jalo
