$468 Cheap Lufthansa flights from Des Moines to Brussels (DSM to BRU)

Find The Best Day To Fly from Des Moines to Brussels

Amazing Lufthansa DSM to BRU Flight Deals

The cheapest flights to Brussels - National found within the past 7 days were $640 round trip and $468 one way. Prices and availability subject to change. Additional terms may apply.

Mon, Nov 24 - Tue, Dec 2
DSM
Des Moines
BRU
Brussels
$640 Roundtrip, found 4 days ago
$640
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Mon, Nov 24 from Des Moines to Brussels, returning Tue, Dec 2, priced at $640 found 4 days ago
Mon, Nov 24 - Tue, Dec 2
DSM
Des Moines
BRU
Brussels
$648 Roundtrip, found 4 days ago
$648
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Mon, Nov 24 from Des Moines to Brussels, returning Tue, Dec 2, priced at $648 found 4 days ago
Mon, Nov 24 - Tue, Dec 2
DSM
Des Moines
BRU
Brussels
$651 Roundtrip, found 4 days ago
$651
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Mon, Nov 24 from Des Moines to Brussels, returning Tue, Dec 2, priced at $651 found 4 days ago
Tue, Oct 28 - Fri, Nov 7
DSM
Des Moines
BRU
Brussels
$676 Roundtrip, found 1 day ago
$676
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Oct 28 from Des Moines to Brussels, returning Fri, Nov 7, priced at $676 found 1 day ago
Tue, Oct 28 - Fri, Nov 7
DSM
Des Moines
BRU
Brussels
$679 Roundtrip, found 1 day ago
$679
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Oct 28 from Des Moines to Brussels, returning Fri, Nov 7, priced at $679 found 1 day ago
Tue, Oct 28 - Fri, Nov 7
DSM
Des Moines
BRU
Brussels
$707 Roundtrip, found 1 day ago
$707
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Oct 28 from Des Moines to Brussels, returning Fri, Nov 7, priced at $707 found 1 day ago
Lufthansa Airports
Hop on a(n) Lufthansa flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
FRADEUFrankfurt Intl.56
ORDUSAO'Hare Intl.25
HNDJPNHaneda24
YYZCANPearson Intl.13
MUCDEUFranz Josef Strauss Intl.12
DENUSADenver Intl.12
IADUSAWashington Dulles Intl.10
ICNKORIncheon Intl.9
TXLDEUTegel6
HAMDEUHamburg5

Travelers ❤️ these 🏨 after their flight to Brussels

Sheraton Brussels Airport Hotel
Sheraton Brussels Airport Hotel
4 out of 5
Brussels National Airport, Zaventem
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.8/10 Excellent! (1,149 reviews)
"空港からのアクセスがよく、広くて清潔なお部屋で快適でした。　"

Reviewed on Jun 7, 2025

Sheraton Brussels Airport Hotel
pentahotel Brussels Airport
pentahotel Brussels Airport
3 out of 5
Berkenlaan 5, Diegem, Machelen
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
7.6/10 Good! (705 reviews)
Good short stay
"Everything is just enough"

Reviewed on Apr 10, 2025

pentahotel Brussels Airport
Holiday Inn Express Brussels Airport by IHG
Holiday Inn Express Brussels Airport by IHG
Berkenlaan 6A, Machelen
A restaurant and a bar/lounge are featured at this hotel. Enjoy freebies like buffet breakfast and a roundtrip airport shuttle Self parking, a coffee shop, and ...
8.6/10 Excellent! (184 reviews)
"Shuttle information not clear -it does not run all day"

Reviewed on Jun 4, 2025

Holiday Inn Express Brussels Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.