$304 Cheap American Airlines flights from Mobile to Columbia (MOB to CAE)

Find The Best Day To Fly from Mobile to Columbia

Amazing American Airlines MOB to CAE Flight Deals

The cheapest flights to Columbia Metropolitan found within the past 7 days were $465 round trip and $304 one way. Prices and availability subject to change. Additional terms may apply.

Sat, Nov 29 - Tue, Dec 9
MOB
Mobile
CAE
Columbia
$465 Roundtrip, found 2 hours ago
$465
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Nov 29 from Mobile to Columbia, returning Tue, Dec 9, priced at $465 found 2 hours ago
Sat, Nov 29 - Mon, Dec 8
MOB
Mobile
CAE
Columbia
$466 Roundtrip, found 2 hours ago
$466
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Nov 29 from Mobile to Columbia, returning Mon, Dec 8, priced at $466 found 2 hours ago
Sat, Nov 29 - Sat, Dec 6
MOB
Mobile
CAE
Columbia
$469 Roundtrip, found 2 hours ago
$469
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Nov 29 from Mobile to Columbia, returning Sat, Dec 6, priced at $469 found 2 hours ago
Wed, Dec 3 - Tue, Dec 9
MOB
Mobile
CAE
Columbia
$474 Roundtrip, found 2 hours ago
$474
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Mobile to Columbia, returning Tue, Dec 9, priced at $474 found 2 hours ago
Wed, Dec 3 - Mon, Dec 8
MOB
Mobile
CAE
Columbia
$475 Roundtrip, found 2 hours ago
$475
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Mobile to Columbia, returning Mon, Dec 8, priced at $475 found 2 hours ago
Tue, Dec 2 - Tue, Dec 9
MOB
Mobile
CAE
Columbia
$486 Roundtrip, found 2 hours ago
$486
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Dec 2 from Mobile to Columbia, returning Tue, Dec 9, priced at $486 found 2 hours ago
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.2/10 Very Good! (1,000 reviews)
Most part .

Reviewed on Nov 17, 2025

Country Inn & Suites by Radisson, Columbia Airport, SC
Sleep Inn Airport

Sleep Inn Airport

2.5 out of 5
2208 A Edmund Hwy West Columbia SC
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
7.6/10 Good! (813 reviews)
Basic room at a decent price. Near the ramp to 26, but not the best area of town. Great staff though, very helpful and accommodating.

Reviewed on Oct 28, 2025

Sleep Inn Airport
Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...
7.4/10 Good! (436 reviews)
Staff was great

Reviewed on Nov 17, 2025

Motel 6 West Columbia, SC - Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.