American Airlines Flight 4521 Deals & Information (2026/2027)

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American Airlines Flight 4521 Route Deals From $141

The cheapest prices found with in the last 7 days for return flights were $373 and $141 for one-way flights to Logan Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Mar 24 - Tue, Mar 30
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$373 Roundtrip, found 11 hours ago
$373
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Mar 24 from Greater Rochester Intl. to Logan Intl., returning Tue, Mar 30, priced at $373 found 11 hours ago
Fri, Nov 13 - Sat, Nov 14
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$379 Roundtrip, just found
$379
Roundtrip
just found
Select American Airlines flight, departing Fri, Nov 13 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 14, priced at $379 just found
Wed, Mar 24 - Tue, Mar 30
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$383 Roundtrip, found 11 hours ago
$383
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Mar 24 from Greater Rochester Intl. to Logan Intl., returning Tue, Mar 30, priced at $383 found 11 hours ago
Fri, Nov 13 - Sat, Nov 14
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$390 Roundtrip, just found
$390
Roundtrip
just found
Select American Airlines flight, departing Fri, Nov 13 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 14, priced at $390 just found
Mon, Nov 23 - Sat, Nov 28
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$390 Roundtrip, found 1 day ago
$390
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 23 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 28, priced at $390 found 1 day ago
Fri, Nov 13 - Sat, Nov 14
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$400 Roundtrip, just found
$400
Roundtrip
just found
Select American Airlines flight, departing Fri, Nov 13 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 14, priced at $400 just found
Mon, Nov 23 - Sat, Nov 28
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$411 Roundtrip, found 1 day ago
$411
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 23 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 28, priced at $411 found 1 day ago
Sat, Jan 2 - Mon, Jan 4
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$413 Roundtrip, found 11 hours ago
$413
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Jan 2 from Greater Rochester Intl. to Logan Intl., returning Mon, Jan 4, priced at $413 found 11 hours ago
Sat, Nov 21 - Sat, Nov 28
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$414 Roundtrip, found 4 days ago
$414
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Nov 21 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 28, priced at $414 found 4 days ago
Wed, Dec 2 - Sun, Dec 6
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$415 Roundtrip, found 4 days ago
$415
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 2 from Greater Rochester Intl. to Logan Intl., returning Sun, Dec 6, priced at $415 found 4 days ago
Wed, Mar 24 - Tue, Mar 30
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$417 Roundtrip, found 11 hours ago
$417
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Mar 24 from Greater Rochester Intl. to Logan Intl., returning Tue, Mar 30, priced at $417 found 11 hours ago
Mon, Nov 23 - Sat, Nov 28
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$421 Roundtrip, found 1 day ago
$421
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 23 from Greater Rochester Intl. to Logan Intl., returning Sat, Nov 28, priced at $421 found 1 day ago
Wed, Mar 24 - Tue, Mar 30
ROC
Greater Rochester Intl.
BOS
Logan Intl.
$427 Roundtrip, found 11 hours ago
$427
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Mar 24 from Greater Rochester Intl. to Logan Intl., returning Tue, Mar 30, priced at $427 found 11 hours ago

Frequently asked questions

What route does flight number AA4521 take?
AA4521 is used on multiple routes, but the most common is between CLT and Memphis Intl. Airport (MEM). If your flight is direct, you'll disembark the plane in 1 hour and 49 minutes. Multi-stop flights can also operate under this number, as can services on other routes.
What kind of plane is on flight number AA4521?
If you've booked a ticket on flight AA4521 from Charlotte-Douglas Intl. Airport (CLT) to Memphis, TN Airport (MEM-Memphis Intl.), there's a strong chance you'll be traveling aboard the Embraer 175. Flight AA4521 serves several routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4521 flight with Travelocity, please visit our Customer Service Portal.