Cheap Flights to Santa Cruz from $119

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How Much Does it Cost To Fly To Santa Cruz?

The cheapest prices found with in the last 7 days for return flights were $183 and $119 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
EZESantiagoApril 8 to April 18$185
GRUSantiagoJune 5 to June 12$258
MIASantiagoApril 27 to May 3$398
YYZSantiagoApril 7 to April 21$601
JFKSantiagoApril 15 to April 23$731
LGASantiagoApril 15 to April 23$755
LAXSantiagoMay 1 to May 10$793
CCSSantiagoApril 16 to May 7$825
MADSantiagoJune 3 to June 23$907
FCOSantiagoMarch 27 to April 11$1,399
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
GRUSantiagoMarch 21 to March 28$278
EZESantiagoMarch 21 to March 26$307
MIASantiagoMarch 22 to April 21$531
JFKSantiagoMarch 21 to March 30$828
LGASantiagoMarch 20 to March 25$837
LAXSantiagoMarch 22 to March 27$920
CCSSantiagoMarch 20 to April 14$1,088
MADSantiagoMarch 22 to March 31$1,247
*Prices include taxes and fees

Santa Cruz Flight Information

Traveling to
Santa Cruz
Lowest Price
$183
Number of Airlines Serving
Airlines Serving
SKY AIRLINE
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Luxury Hotels in Santa Cruz

TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
$150 nightly
The price is $150 total per night from Mar 16 to Mar 17
$150 total
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (212 reviews)
The hotel had a great buffet breakfast which was included with your stay. The staff were helpful and friendly would offer to book restaurant reservations. The only complaint was we found the air conditioner fan to loud.

Reviewed on Mar 12, 2026

Opens in a new windowTerraViña
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Hotel Boutique Solaz Bella Vista de Colchagua

Hotel Boutique Solaz Bella Vista de Colchagua

3 out of 5
San Pedro de Callihue Lote 5 J Santa Cruz O'Higgins
$76 nightly
The price is $76 total per night from Mar 24 to Mar 25
$76 total
Mar 24 - Mar 25
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza de Armas are ...
9.4/10 Exceptional! (98 reviews)
The hotel was in a great location and the garden and pool made it a very relaxing place to stay. All the staff were so friendly and helpful - they had given great advice before we arrived and booked wine tours for us which made our stay all the more enjoyable! Breakfast was also really good. We would ...

Reviewed on Jan 29, 2026

Opens in a new windowHotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

3.5 out of 5
Ismael Valdes 92 Santa Cruz O'Higgins
$123 nightly
The price is $123 total per night from Mar 16 to Mar 17
$123 total
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
9.2/10 Wonderful! (138 reviews)
A comfortable, family run friendly place to stay. It's a bit quirky, and full of interesting memorabilia, but just perfect for us, with a swimming pool and a couple of excellent restaurants within 1 min walking for dinner. Spot on.

Reviewed on Jan 10, 2026

Opens in a new windowHotel Boutique Vendimia Premium
Santa Cruz Plaza
Great for families

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
$126 nightly
The price is $126 total per night from Apr 5 to Apr 6
$126 total
Apr 5 - Apr 6
Book a stay at this spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (347 reviews)

Families like: Outdoor pool, kids club, babysitting, bicycle rentals

Travelers say...
Mostly clean room, wonderful staff

Reviewed on Mar 2, 2026

Opens in a new windowSanta Cruz Plaza
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La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
$89 nightly
The price is $89 total per night from Mar 19 to Mar 20
$89 total
Mar 19 - Mar 20
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9.2/10 Wonderful! (110 reviews)
Excellent Staff, excellent facilities, and an excellent sleep in a very quiet location.

Reviewed on Feb 13, 2026

Opens in a new windowLa Perla Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santa Cruz Flight and Hotel Packages

Santa Cruz flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Fauna Hotel
Casablu Hotel
Hotel Palacio Astoreca
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Need a Car For After Your Flight?

Lowest prices found within the past 3 days. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Which airlines fly to Santa Cruz?
Lock in a fare with one of the 17 airlines that travel to Santa Cruz an enjoy an amazing new adventure. Carriers that come with top reviews include:

  • LATAM Airlines
  • Sky Airline
  • JetSMART

Where to stay in Santa Cruz
Start making those dreams about Santa Cruz come true by reserving your accommodations with Travelocity. With 37 terrific options at your fingertips, we know you'll find the perfect place to lay your head.Securing accommodations can often be a little tiresome. Make the process as easy as possible and check out some of our top suggestions, the Santa Cruz Plaza and the Casa Suiza.
Places to visit in Santa Cruz
Discover the protracted and interesting history of Plaza de Armas. Need some more ideas? A day touring Museo de Colchagua is a wonderful way to learn about regional history away from the crowded tourist sites. And there's more. A trip to Laura Hartwig Winery is a journey for your palate.
How to get through airport security fast when traveling to Santa Cruz
If you like the idea of spending more time at the airport bars and restaurants and less time at the security checkpoint on your way to Santa Cruz, follow these practical tips:

  • Keep your boarding pass and passport easily accessible. They'll be the first things you'll be asked for by security staff.
  • Coins, belts and keys are to be placed in a tub for X-raying. If you walk into the body scanner with these items, you'll be turned around and requested to remove them.
  • Laptops must be removed from their protective carriers and placed in a tub for inspection.
  • When it comes to flying with liquids or gels, each passenger is permitted a quart-sized clear resealable bag to keep containers no larger than 3.4 ounces (100 milliliters).
  • Give some thought to the type of footwear you want to fly in. Slippers are awesome because they're easy to take off for the airport security checks. Try wearing some on your next flight!
  • Some countries have strict biosecurity laws. Consider where you're headed to and whether or not you can travel with unpackaged foods.

Plane Tickets To Santa Cruz

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.