This apartment was fantastic. The apartment itself is lovely- high ceilings, two good bathrooms, comfortable beds, good air conditioning independently controlled in each room, a dock directly on the building for water taxis, and multiple windows looking out directly onto the Grand Canal.
While everyone has their own favorite neighborhood, I believe the location to be fantastic. Close to the Grand Canal, short walk to the Accademia bridge, a quiet neighborhood, close to several restaurants and bakeries (I found Osteria Enoteca Ai Artisti to be fantastic). It is close enough to easily walk to popular locations like St. Mark's, but enough removed that the nearby streets are not busy. There is something in this neighborhood for everyone- some small shops, gelato, pizza by the slice, and a couple very good museums.
Finally, the contact person, Enrica, was absolutely fantastic. She was able to answer any questions quickly via WhatsApp, and also booked multiple water taxis/airport transfers for us (including one at 3:15 am to catch an early flight).
Overall, this place was a 10/10.